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ahellab.bsky.social
did:plc:wiywienpmotj7z5fqa25u74l
A few years back we discovered a dual hybrid protein modification composed of ADP-ribose dinucleotide and ubiquitin (ADPr-Ub). Now we reveal that ADPr-Ub can be further ubiquitinated by the E3 ubiquitin ligase RNF114!
https://www.nature.com/articles/s41467-025-61111-7
https://www.science.org/doi/10.1126/sciadv.add4253
2025-07-10T06:11:42.842Z