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Andrew Stern
andrewmstern.bsky.social
did:plc:gpisa5t4x4eqkx7vxnt7spoy
We studied the binding of clinical antibodies to human brain extracts and found no evidence that lecanemab binds a more soluble population of Abeta than aducanumab or donanemab, nor that binding preferences to CAA vs plaque explained different ARIA rates. https://www.biorxiv.org/content/10.1101/2025.05.20.654902v1
2025-05-21T23:27:50.545Z