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Corentin Claeys Bouuaert
ccb-lab.bsky.social
did:plc:3tkzfqmgqbn75o3cytfgu5gx
Now on two the second surprise: The Mer2 coiled coil domain that binds Spp1 is also involved in DNA binding.
We reconstituted Mer2-Spp1-DNA complexes and used AlphaFold to visualize what these complexes might look like.
(these models look pretty cool but are to be taken with a big grain of salt)
2025-09-28T18:15:09.986Z