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Roberto Chica Lab
chicalab.bsky.social
did:plc:ewcrd3pyisorjeiinh2n3x6t
How do mutations far from an enzyme's active site influence catalysis? 🤔
Part 2: In collaboration with @fraserlab.bsky.social and @silviaosuna.bsky.social, we investigated this question using de novo Kemp eliminases, revealing effects of distal mutations on the catalytic cycle. 🧵 (1/6)
2025-02-28T17:09:42.456Z