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Communications Biology
commsbio.nature.com
did:plc:5u6dp4ed5xyuf6nbihfzq3wj
In living cells, ligand-bound GPCRs are internalized, packaged into the extracellular vesicles, and released. By utilizing this pathway as a screening platform, one can efficiently generate a high-performance DNA aptamer drug for a specific GPCR. 🎯
https://www.nature.com/articles/s42003-026-10525-0
https://doi.org/10.1038/s42003-026-10525-0
2026-07-23T13:57:55.771Z