Associate professor studying antibiotics and host-pathogen interactions at UNC Chapel Hillhttps://bsky.app/profile/bconlon.bsky.socialhttps://bsky.app/profile/bconlon.bsky.social/post/3mpo6dblk4s2yLoss of O-antigen due to wbbL mutations is common and associated with increased mortality in Escherichia coli bloodstream infections | Science Advances https://www.science.org/doi/10.1126/sciadv.aec4661?__cf_chl_f_tk=hhe5z6vcWrchb5jALlymOwNBseR8TpF33Vn.GKDWy_E-1783000080-1.0.1.1-cE2Z8sOMZtm9kDh6IAnkT1ra0JHSIfnK6CUO.sW8Bh802 Jul 2026 13:49 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3mpo6dblk4s2yhttps://bsky.app/profile/bconlon.bsky.social/post/3mcflk6bfcs2iCongratulations to MD-PhD student, Amanda Velez and all co-authors on our new PNAS paper describing how the innate immune protein calprotectin incapacitates autolysins, inducing tolerance to B-lactam antibiotics. A fun collaboration with Thomas Kehl-Fie. https://www.pnas.org/doi/10.1073/pnas.251346212314 Jan 2026 17:24 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3mcflk6bfcs2ihttps://bsky.app/profile/bconlon.bsky.social/post/3m2trenhri22yDelighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better https://www.nature.com/articles/s41564-025-02124-210 Oct 2025 13:24 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3m2trenhri22yhttps://bsky.app/profile/bconlon.bsky.social/post/3lykosncby22oLooking to hire a postdoctoral associate to examine how antibiotics frequently fail in vivo and identifying new ways to make them work better. https://unc.peopleadmin.com/postings/30649611 Sep 2025 11:53 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3lykosncby22ohttps://bsky.app/profile/bconlon.bsky.social/post/3ljldo6vjvk2ehttps://www.nih.gov/news-events/nih-research-matters/diabetes-boosts-antibiotic-resistance-mice Nice to see our recent paper highlighted in NIH - Research Matters newsletter04 Mar 2025 20:49 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3ljldo6vjvk2ehttps://bsky.app/profile/bconlon.bsky.social/post/3li2mkyuzns2jDelighted to share our new study. A collaboration with the Thurlow lab. Antibiotic resistance rapidly emerges and thrives in diabetic mice. A worrying coming together of two major and growing health problems worldwide https://www.science.org/doi/10.1126/sciadv.ads159113 Feb 2025 11:48 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3li2mkyuzns2jhttps://bsky.app/profile/bconlon.bsky.social/post/3lazmv3rad22fCongratulations Lauren! Great work! [contains quote post or other embedded content]16 Nov 2024 00:24 +0000at://did:plc:237vlp2h7thiebvmbx6o7gtr/app.bsky.feed.post/3lazmv3rad22f