Independent Research Group @ the Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany @mpi-nat.bsky.social We love ubiquitin, kinases, and good food.https://bsky.app/profile/sonjalorenzlab.bsky.socialhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3mqgjk2tnys2cFantastic science and fantastic atmosphere at the Ubiquitin Fusion Meeting in Portugal! Many thanks to the organizing team: Florian Bassermann, Henning Walczak, and Vishva Dixit.12 Jul 2026 06:13 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3mqgjk2tnys2chttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3mlte4ctirs24Fantastic to be back at Oxford, where I completed my PhD. The Biochemistry Department @oxfordbiochemistry.bsky.social continues to be a true powerhouse of excellence and innovation. A sincere thank you to @robklose.bsky.social and @elliottlab.bsky.social for the invitation and the inspiring science!14 May 2026 17:35 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3mlte4ctirs24https://bsky.app/profile/sonjalorenzlab.bsky.social/post/3mltdtpu5ok2qOver the past 5 years, 50 structures of full-length HECT-type ligase constructs have been deposited in the PDB. What have we learned from these studies, and what key questions remain open? Check out our new review on this exciting and fast-moving field: https://www.jbc.org/article/S0021-9258(26)00310-8/fulltext14 May 2026 17:30 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3mltdtpu5ok2qhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3mkyyz2pfhs2bPassionate about ubiquitin biology, its mechanistic underpinnings and therapeutic exploitation? We are looking for a PhD student or postdoc to join our team. Applications and informal inquiries welcome! https://www.mpinat.mpg.de/19-26?c=389579604 May 2026 06:07 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3mkyyz2pfhs2bhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3meqz7trdlk2yCongratulations, Dr. Banos! I am so happy that we will have the opportunity to continue working together in the coming years. Thanks so much to all supporters of Blanca's research and career! [contains quote post or other embedded content]13 Feb 2026 17:18 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3meqz7trdlk2yhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3mbo7j2yzb226Sledding to the lab - what a great way to start the year! Have a fantastic 2026, everybody!05 Jan 2026 10:17 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3mbo7j2yzb226https://bsky.app/profile/sonjalorenzlab.bsky.social/post/3m4dlf4ugfk2qExciting! Yet another Spotlight article has come out today in @cp-trendsparasitol.bsky.social, featuring our work on kinase-ligase crosstalk in a Leishmania virulence factor. Thanks so much, @jnpruneda.bsky.social and Shun-Je Bhark! https://www.sciencedirect.com/science/article/pii/S1471492225002995?dgcid=author29 Oct 2025 13:44 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3m4dlf4ugfk2qhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3m4d3wla47c2xThanks so much, Richard de Heiden and Monique Mulder, for featuring exciting findings on drug-like small-molecule ubiquitination by my research group and that of Jonathan Ostrem. Check out thisTiBS spotlight: https://www.sciencedirect.com/science/article/pii/S0968000425002452?dgcid=coauthor29 Oct 2025 09:08 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3m4d3wla47c2xhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3m3momvlqn227Exciting opening for a lab technician in the Rink department @mpi-nat.bsky.social: www.mpinat.mpg.de/5123253/36-25 The lab is looking for a technician to support and develop next-generation sequencing applications. Please forward the announcement: https://www.mpinat.mpg.de/5123253/36-2520 Oct 2025 11:11 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3m3momvlqn227https://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lzlqx3mmhk23Allosteric activation of a ubiquitin ligase by an internal kinase domain! Congratulations to our team member Thornton Fokkens for this fascinating discovery in a neglected disease area with strong therapeutic need. Many thanks to all our great collaborators! https://www.sciencedirect.com/science/article/pii/S109727652500743924 Sep 2025 15:30 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lzlqx3mmhk23https://bsky.app/profile/sonjalorenzlab.bsky.social/post/3ly6kmsuw3s2rJoin us - in person or online - for the Göttinger Literaturherbst, a literature festival with a unique science series. We will feature Katalin Karikó, among other research leaders. Honoured to host Julian Nida-Rümelin on the pressing topic of democracy, 29 Oct. https://www.mpinat.mpg.de/5094670/pr_251606 Sep 2025 16:07 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3ly6kmsuw3s2rhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lxyg37s23s2hWe’re excited that our article on the ubiquitination of drug-like small molecules in cells has been selected as an Editorial Highlight in #NatureCommun! 🎉 Check it out here 👉 https://www.nature.com/ncomms/editorshighlights04 Sep 2025 05:29 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lxyg37s23s2hhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lxu2pfys6c27Delighted to share our work on cellular ubiquitination of drug-like compounds by HUWE1 - a surprising journey! Kudos to all contributors & first authors, Barbara Orth and Pavel Pohl. Sincere thanks to @ireserra.bsky.social ‬ #NatCommun for expertly guiding the winding publishing path. rdcu.be/eDzPk https://rdcu.be/eDzPk02 Sep 2025 11:55 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lxu2pfys6c27https://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lxrfqsv26c2cAre you interested in a science policy career? Check out this interesting opening an EMBO! https://www.embo.org/vacancy/policy-assistant-embo-policy-programme/01 Sep 2025 10:35 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lxrfqsv26c2chttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lxm4jde6zs2zCongrats to our lab member, Sait! And thanks very much to all who supported his application! Looking forward to great discoveries to come. [contains quote post or other embedded content]30 Aug 2025 08:06 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lxm4jde6zs2zhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lusomwhz5k27Congratulations to our lab member, Dr. Thornton Fokkens, for his outstanding research, flawless PhD defense, and smooth climb to the Gänseliesel, the Göttingen landmark that is kissed by all new graduates!25 Jul 2025 18:31 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lusomwhz5k27https://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lssmwlyvfk2eCongratulations to our fantastic @mpi-nat.bsky.social student representatives at the Lindau Nobel Laureates Meeting! Have fun! #LINO25 Delighted that Rosi Junker from @sonjalorenzlab.bsky.social can attend. Many thanks to all supporters, including Brenda Schulman, @embo.org and GGNB Goettingen!30 Jun 2025 07:10 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lssmwlyvfk2ehttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lm5fhsc2k22yFantastic Ubiquitin CSH Meeting! Great science, reunion with old friends and many new contacts. Thanks to the master organizers: @annebertolotti.bsky.social, @labthoma.bsky.social, and Achim Werner!06 Apr 2025 11:59 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lm5fhsc2k22yhttps://bsky.app/profile/sonjalorenzlab.bsky.social/post/3lm5em44qx223Hi! Our lab has moved to Bluesky! We will discontinue our Twitter presence in the near future, so please watch out our news here!06 Apr 2025 11:44 +0000at://did:plc:2cpuacb2dyouxxapoesctrqp/app.bsky.feed.post/3lm5em44qx223