We are a cryoEM-focused US-based CRO (we own 3 microscopes on the West Coast, and 3 microscopes on the East Coast), and we acquired Proteos in Kalamazoo, MI, in January of this year. Contact us for cryoEM, gene-to-structure, or protein production.https://bsky.app/profile/nanoimaging.bsky.socialhttps://bsky.app/profile/nanoimaging.bsky.social/post/3m3b4djlkhk2jNeed support for your protein degrader projects? Join our webinar for insights into our gene-to-structure workflow for producing high-quality, structure-grade CRBN-DDB1 ready for structure determination. Register: https://nimgs.zoom.us/webinar/register/WN_nFn0JGwDQ52Q7VyBqo00Gg#/registration15 Oct 2025 20:45 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3m3b4djlkhk2jhttps://bsky.app/profile/nanoimaging.bsky.social/post/3m2jylybw762u🧪 Just two days away! Join us for a gene-to-structure case study, from protein production to a 3.1 Å structure for CYP3A4, a 57 kDa cytochrome P450 monooxygenase and ask your questions live. BONUS: Sign up for the webinar to get early access to the whitepaper! https://nimgs.zoom.us/webinar/register/4017551078421/WN_JsgAhOxgTs2fnyxwD1mTGA https://nimgs.zoom.us/webinar/register/5117551078351/WN_JsgAhOxgTs2fnyxwD1mTGA06 Oct 2025 16:06 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3m2jylybw762uhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lzlwgta7ix2h🧪 Conflicting results from DLS? #CryoTEM imaging can provide quantitative and qualitative data for smaller particles, like iron nanoparticle formulations, all in one study. Reach out to nischr@nanoimagingservices.com to learn how cryo-TEM imaging can help you meet milestones faster.24 Sep 2025 17:08 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lzlwgta7ix2hhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lygftfik6l2n🧪 Running into roadblocks with your proteins? Join us for a guide to setting your structure determination project up for success and case study of CYP3A4, a 57 kDa cytochrome P450 monooxygenase solved to 3.1 Å. P.S. Get early access to the case study by registering! https://nimgs.zoom.us/webinar/register/4617551077426/WN_JsgAhOxgTs2fnyxwD1mTGA09 Sep 2025 19:02 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lygftfik6l2nhttps://bsky.app/profile/nanoimaging.bsky.social/post/3ly45dzd6i42x🚀 Fast track your #HPV therapeutics with #cryoTEM imaging. From initial characterization to 3D structures, we support you throughout the entire pipeline, including regulatory submissions. 🧪 Want the proof? See our published work on Gardasil®: https://www.nanoimagingservices.com/resources/how-vlp-structural-insights-from-cryo-tem-helped-characterize-the-gardasil-r-vaccine05 Sep 2025 17:04 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3ly45dzd6i42xhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lxfmxobrvc26🧪 Skip the trial and error for structure determination of soluble proteins. Join the #webinar 10/8 for a gene-to-structure case study of CYP3A4, a 57 kDa cytochrome P450 monooxygenase, solved to 3.1 Å by #cryoEM. https://nimgs.zoom.us/webinar/register/6817551076114/WN_JsgAhOxgTs2fnyxwD1mTGA27 Aug 2025 18:12 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lxfmxobrvc26https://bsky.app/profile/nanoimaging.bsky.social/post/3lwevybqif22p🧪 Are you using cryo-EM to look at small soluble proteins? Walk through each stage from protein production to structure determination, with practical insights and lessons from a recent case study on CYP3A4 with live Q&A. Register: https://nimgs.zoom.us/webinar/register/8917551075532/WN_JsgAhOxgTs2fnyxwD1mTGA14 Aug 2025 17:56 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lwevybqif22phttps://bsky.app/profile/nanoimaging.bsky.social/post/3lvqokxfyws2nWhen it comes to #lentivirus characterization, seeing is believing. Traditional analytical methods tell you what's there, but #cryoTEM shows you exactly how it's organized. Learn more: https://www.nanoimagingservices.com/nanoparticle-characterization/nano-samples/lentivirus06 Aug 2025 16:50 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lvqokxfyws2nhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lvoc4uy76f2pHow do you choose a nanoparticle characterization method? While there are many techniques available, cryo-TEM stands out by revealing information other methods miss. Dive into the comparison: https://www.nanoimagingservices.com/about/blog/visualizing-nanomedicines-understanding-your-nanoparticle-formulations05 Aug 2025 18:02 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lvoc4uy76f2phttps://bsky.app/profile/nanoimaging.bsky.social/post/3lvdxnjefcs2zEver wondered how buffers impact #cryoEM structures? 🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact01 Aug 2025 15:27 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lvdxnjefcs2zhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lukyf4teip2kAre you looking for comprehensive, reliable particle sizing analysis? From LNPs to iron nanoparticles, cryo-TEM semi-automated particle contouring and sizing provides precise particle size distribution measurement for a range of samples. Learn more at https://www.nanoimagingservices.com/nanoparticle-characterization/nano-services/particle-size-distribution22 Jul 2025 17:04 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lukyf4teip2khttps://bsky.app/profile/nanoimaging.bsky.social/post/3luaov4szfs2v🧪 Ever wondered what the difference is between #cryoEM and #negativestain #TEM is? Find out in today's FAQ Friday!18 Jul 2025 14:47 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3luaov4szfs2vhttps://bsky.app/profile/nanoimaging.bsky.social/post/3ltzf2vht442vDo you know how #LNPs show up in #cryoTEM versus negative stain TEM? Want to learn more about the advantages of cryo-TEM for LNPs and other #liposomal samples? Tune in for the full webinar from Dr. Maria (Mandy) Janssen: https://youtu.be/TPZdaILFAGA?t=97&si=SLoGWhI5ASZkaPh415 Jul 2025 17:03 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3ltzf2vht442vhttps://bsky.app/profile/nanoimaging.bsky.social/post/3ltfenmwv4a2hDuring a recent webinar, we were asked, “How does automated cryo-TEM particle picking for AAV full/empty capsids compare to other orthogonal methods?” Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI07 Jul 2025 18:02 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3ltfenmwv4a2hhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lsh732uwlu2oPoor contrast TEM images got you feeling grey? No problem! Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication: https://www.nanoimagingservices.com/about/blog/enhancing-contrast-and-adding-scale-bars-to-tem-images25 Jun 2025 18:03 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lsh732uwlu2ohttps://bsky.app/profile/nanoimaging.bsky.social/post/3lrvih2c35l25Did you miss our webinar last week? You can now catch this amazing talk from Dr. Mandy Janssen about #cryoTEM #LNP characterization, NIS’s proprietary AI tools for image analysis, and a case study showing unique insights only cryo-TEM can provide. Catch it here: https://youtu.be/TPZdaILFAGA18 Jun 2025 17:03 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lrvih2c35l25https://bsky.app/profile/nanoimaging.bsky.social/post/3lrsvmaqrnk2kAre you struggling to solve the structure of your #RNA molecule? Cryo-EM study RNA in its native, unbound state, without the influence of associated proteins? Learn more about the potential of #cryoEM single particle analysis for protein-free RNA: https://www.nanoimagingservices.com/about/blog/unlocking-the-secrets-of-rna-protein-free-structure-determination-with-cryo-electron-microscopy17 Jun 2025 16:20 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lrsvmaqrnk2khttps://bsky.app/profile/nanoimaging.bsky.social/post/3lrbaxbjao22kUnexpected results in your #LNP formulations? Join our webinar + Q&A to learn how #cryoTEM imaging can help provide answers. We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset. Sign up: https://nimgs.zoom.us/webinar/register/3017495707912/WN_lsvkkXOvTMyBos7XAQJC_A10 Jun 2025 15:55 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lrbaxbjao22khttps://bsky.app/profile/nanoimaging.bsky.social/post/3lqukqefld224Have you signed up yet? In just 1 week, Dr. Mandy Janssen will be giving a webinar + Q&A diving into the applications of #cryoTEM for #LNP development! Don't miss out on this deep dive: https://nimgs.zoom.us/webinar/register/2017491344115/WN_lsvkkXOvTMyBos7XAQJC_A Can't make it live? Sign up to get a recording, or send in your questions!05 Jun 2025 14:46 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lqukqefld224https://bsky.app/profile/nanoimaging.bsky.social/post/3lqfpnllahr2oFAQ Friday! Dr. Sarah Strassler Sulley touches on the differences between cryo-EM and HDX for epitop emapping. Want more? Check out our blog with an in-depth technique comparison: https://www.nanoimagingservices.com/about/blog/epitope-mapping-for-drug-discovery30 May 2025 17:04 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lqfpnllahr2ohttps://bsky.app/profile/nanoimaging.bsky.social/post/3lpkbo2pi7k2dLooking for ways to enhance your #LNP analysis tools? Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset. Questions? Stick around after the webinar for a Q&A with Mandy. Sign up: https://nimgs.zoom.us/webinar/register/8517476801916/WN_lsvkkXOvTMyBos7XAQJC_A19 May 2025 19:12 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lpkbo2pi7k2dhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lpcj2hu2rw2lHow big are cryo-EM grids exactly? Find out!16 May 2025 17:02 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lpcj2hu2rw2lhttps://bsky.app/profile/nanoimaging.bsky.social/post/3lp5ijob3w222It's tomorrow! Join us to learn about automated cryo-TEM analysis of AAV full/empty capsid ratios. Can't make it? Sign up anyway to receive a recording. Don't miss this webinar + Q&A session: https://nimgs.zoom.us/webinar/register/6017472425183/WN_3xY8HsA4Q9qA2Wr8dBn7jQ14 May 2025 17:10 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lp5ijob3w222https://bsky.app/profile/nanoimaging.bsky.social/post/3loycivhqyc2aWebinar! Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements. Register: https://nimgs.zoom.us/webinar/register/3817470614427/WN_lsvkkXOvTMyBos7XAQJC_A12 May 2025 15:39 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3loycivhqyc2ahttps://bsky.app/profile/nanoimaging.bsky.social/post/3loqyrz33ds2aOne week out! Join us for a webinar, "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios". Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions. Sign up: https://nimgs.zoom.us/webinar/register/8617468133443/WN_3xY8HsA4Q9qA2Wr8dBn7jQ09 May 2025 17:56 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3loqyrz33ds2ahttps://bsky.app/profile/nanoimaging.bsky.social/post/3lo2k252oe22tDon't miss this webinar! "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios" on 5/15, 11am PST, 2pm EST. Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions. https://nimgs.zoom.us/webinar/register/6817460415489/WN_3xY8HsA4Q9qA2Wr8dBn7jQ30 Apr 2025 19:34 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lo2k252oe22thttps://bsky.app/profile/nanoimaging.bsky.social/post/3lndpfjt5ak2iLive webinar! Learn about automated AAV empty/full capsid ratio analysis with cryo-TEM on Thursday May 15, 11am PST, 2pm EST. Learn the advantages of cryoTEM for assessing AAV formulations & how AAV empty/full capsid status is determined. Sign up: https://nimgs.zoom.us/webinar/register/6417452517454/WN_3xY8HsA4Q9qA2Wr8dBn7jQ21 Apr 2025 17:38 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lndpfjt5ak2ihttps://bsky.app/profile/nanoimaging.bsky.social/post/3ln43xz5kda2wWhat are sample size requirements for Single Particle Analysis cryo-EM? Join Dr. Sarah Strassler Sulley to find out! Questions about cryo-EM? Let us know!18 Apr 2025 17:02 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3ln43xz5kda2whttps://bsky.app/profile/nanoimaging.bsky.social/post/3lmd26ywj4k2wDid you know cryo-TEM is the only technique that can visualize blebbing on LNPs? Check out our latest blog for detailed examples of blebs & bilayers, and a literature review: bit.ly/42oxkWH Email us at nischr@nanoimagingservices.com to get started imaging your lipid nanoparticles!08 Apr 2025 17:54 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3lmd26ywj4k2whttps://bsky.app/profile/nanoimaging.bsky.social/post/3llyvlljkmf2lIt’s FAQ Friday! A well characterized sample can make all the difference for cryo-EM structure determination. What characterization techniques do we recommend? Check in with Dr. Sarah Strassler Sulley to find out! What else do you want to know about cryo-EM? Let us know.04 Apr 2025 17:05 +0000at://did:plc:2hn56yr4tais7rogzsbx77fa/app.bsky.feed.post/3llyvlljkmf2l