BioE PhD student @ Stanford in the Hie Lab // ML for Synthetic Biologyhttps://bsky.app/profile/adititm.bsky.socialhttps://bsky.app/profile/adititm.bsky.social/post/3m5yoirdzms2rWhat if we could autocomplete DNA based on function? Today in @Nature, we share semantic design—a strategy for function-guided design with genomic language models that leverages genomic context to create de novo genes and systems with desired functions. 🧵 https://www.nature.com/articles/s41586-025-09749-719 Nov 2025 16:31 +0000at://did:plc:2kfklu5ivqguzee3xk4gilrh/app.bsky.feed.post/3m5yoirdzms2rhttps://bsky.app/profile/adititm.bsky.social/post/3ldokbsxees2wExcited to have the first project of my PhD out!! By leveraging genomic language model Evo’s ability to learn relationships across genes (i.e., "know a gene by the company it keeps"), we show that we can use prompt-engineering to generate highly divergent proteins with retained functionality. 🧵1/N19 Dec 2024 18:54 +0000at://did:plc:2kfklu5ivqguzee3xk4gilrh/app.bsky.feed.post/3ldokbsxees2w