Associate Professor @ Mass General Hospital & Harvard Medical School Genome editing / Protein eng. / Molecular medicine 🇨🇦🧬 Kayden-Lambert MGH Research Scholar '23-28https://bsky.app/profile/bkleinstiver.bsky.socialhttps://bsky.app/profile/bkleinstiver.bsky.social/post/3mgpzjhc7mc2rInterested in gaining research experience, and curious about genome editing tool development and their application to treat human diseases? 🧬 🧫 We are hiring!! Join us at Mass General Hospital in Boston! 📣 https://massgeneralbrigham.wd1.myworkdayjobs.com/MGBExternal/job/Boston-MA/Research-Lab-Tech-I_RQ405415810 Mar 2026 18:41 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3mgpzjhc7mc2rhttps://bsky.app/profile/bkleinstiver.bsky.social/post/3m3bi4ager22dAn inspirational panel this morning with none other than baby KJ himself - highlighting the stories of heroes @ahrensnicklas.bsky.social & @kiranmusunuru.bsky.social ( hosted by @jasonmast.bsky.social). Crescendo: KJ's Dad on watching 🏈 with his son: "This is what we thought we would never get". ❤️👏 [contains quote post or other embedded content]16 Oct 2025 00:15 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3m3bi4ager22dhttps://bsky.app/profile/bkleinstiver.bsky.social/post/3m3bhnjfhqs2dCongrats to @connorjtou.bsky.social on being named a 2025 #STATWunderkind. His enthusiasm in the lab is contagious and he thrives on doing really hard things. Really well deserved recognition for an innovator and emerging leader in our field! 👏 🙌 @mgbresearch.bsky.social @harvardmed.bsky.social [contains quote post or other embedded content]16 Oct 2025 00:07 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3m3bhnjfhqs2dhttps://bsky.app/profile/bkleinstiver.bsky.social/post/3lym643s73c2eOptimization of a bespoke base editor to treat a severe pediatric vascular disease! 🫀🧬 Our manuscript describes: 1️⃣ Engineering a target-specific BE🧬 2⃣ A *must avoid* bystander edit that occurs with WT SpCas9 BEs! 🙅‍♂️ 3⃣ Extension of lifespan after in vivo editing! 🐁✅ https://www.nature.com/articles/s41551-025-01499-112 Sep 2025 02:00 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3lym643s73c2ehttps://bsky.app/profile/bkleinstiver.bsky.social/post/3lpcihdujec2dLess than one day to celebrate a major win for science, before returning to our regularly scheduled programming of destruction of the American scientific enterprise and capitulation.. [contains quote post or other embedded content]16 May 2025 16:52 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3lpcihdujec2dhttps://bsky.app/profile/bkleinstiver.bsky.social/post/3lpav4wlg6k24An incredible collaborative effort led by @kiranmusunuru.bsky.social @ahrensnicklas.bsky.social @urnov.bsky.social & others. Congratulations to @rachelsilverstein9.bsky.social who designed the Cas9 enzyme that went into this drug. Wishing K.J. & his family all the best 🙏 [contains quote post or other embedded content]16 May 2025 01:33 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3lpav4wlg6k24https://bsky.app/profile/bkleinstiver.bsky.social/post/3lngkwelfqc24In @nature.com we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR enzymes, offering safer & more efficient genome editing tools 🧬🖥️ @rachelsilverstein9.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social https://www.nature.com/articles/s41586-025-09021-y22 Apr 2025 20:56 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3lngkwelfqc24https://bsky.app/profile/bkleinstiver.bsky.social/post/3lkbjvt47722vInterested in learning more about genome editing tool dev & their application to treat human diseases? 🧬 🏥 We're hiring graduating seniors who are seeking ~2 years of post-bac research experience. If you're interested in gaining experience in next gen medicines, please reach out and apply! Link 👇 https://massgeneralbrigham.wd1.myworkdayjobs.com/en-US/MGBExternal/job/Boston-MA/Research-Technician-I---Center-for-Genomic-Medicine_RQ4008964?q=RQ400896413 Mar 2025 16:39 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3lkbjvt47722vhttps://bsky.app/profile/bkleinstiver.bsky.social/post/3linma7pyb22cIf you're unsure whether advocacy or protest to save life-saving research matters, an important message here starting at 33:00. Together we can prevent devastating healthcare & economic impacts, and save science that doesn't see red or blue.. We need your support! ✊🧬🔬🧑‍🔬 https://youtu.be/cw0F8G4-dMw?si=6lugxKjgITxwtJME&t=198021 Feb 2025 01:02 +0000at://did:plc:2mwjjup73vbml7tlixtf4c5r/app.bsky.feed.post/3linma7pyb22c