Physician scientist from LMU Munich trying to understand how to maximise kidney lifespan for patients with kidney diseaseshttps://bsky.app/profile/hjanders.bsky.socialhttps://bsky.app/profile/hjanders.bsky.social/post/3m4flqvq4ss2kNow open access in @ndt-era.bsky.social Rationale, Design, and Baseline Characteristics of the TRANSCEND-CKD trial of Retatrutide in pts with CKD 🧐Retatrutide is a novel triple incretin agonist targeting GIP, GLP-1, and glucagon receptors ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf230/830591130 Oct 2025 08:56 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3m4flqvq4ss2khttps://bsky.app/profile/hjanders.bsky.social/post/3m4ankxi4ls2zNow open access in @ndt-era.bsky.social Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) in Chinese Pts 🧐This Chinese ADTKD cohort reveals a high prevalence of UMOD and HNF1B variants ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf229/830402228 Oct 2025 09:45 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3m4ankxi4ls2zhttps://bsky.app/profile/hjanders.bsky.social/post/3m4ancgnugk2yNow online in @ndt-era.bsky.social Neutrophil infiltration of kidney grafts: incidence, associated factors and graft survival 🧐NTI should prompt the search for urinary tract infection and rejection ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf219/830037228 Oct 2025 09:41 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3m4ancgnugk2yhttps://bsky.app/profile/hjanders.bsky.social/post/3m22pahqfus2bNow online in @ndt-era.bsky.social Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI 🧐RMC-035 may improve kidney outcomes in settings characterized by oxidative and ischemia-reperfusion injury. ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf194/826681730 Sep 2025 14:09 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3m22pahqfus2bhttps://bsky.app/profile/hjanders.bsky.social/post/3m2oeu7gl422eNow open access in @ndt-era.bsky.social How can we target the production of pathogenic IgA in IgAN? 🧐Drugs directed at mucosal B cells, inhibitors of APRIL and BAFF, and drugs that target IgA-producing plasma cells ▶️https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf185/826226208 Oct 2025 09:56 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3m2oeu7gl422ehttps://bsky.app/profile/hjanders.bsky.social/post/3m22pahqfus2bNow online in @ndt-era.bsky.social Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI 🧐RMC-035 may improve kidney outcomes in settings characterized by oxidative and ischemia-reperfusion injury. ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf194/826681730 Sep 2025 14:09 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3m22pahqfus2bhttps://bsky.app/profile/hjanders.bsky.social/post/3lzv4mlznrs2rNow open access in @ndt-era.bsky.social Prevalence of Strongyloides stercoralis in HD pts in Vienna 🧐Implementation of targeted screening for S. stercoralis should be considered in pre-KTX protocols in Europe. ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf192/826653528 Sep 2025 08:52 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lzv4mlznrs2rhttps://bsky.app/profile/hjanders.bsky.social/post/3lztvlcaksk22Now open access in @ndt-era.bsky.social QT-Prolonging Medications: Prevalence of Use and Associated Risks in CKD 🧐The pathophysiological relevance, prevalence, and CV consequences of QT-prolonging drug use in the CKD setting ▶️https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf196/826391527 Sep 2025 21:14 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lztvlcaksk22https://bsky.app/profile/hjanders.bsky.social/post/3lz563vhrc22rNow open access in @NDTsocial Anti-GBM disease - Treatment Standard 🧐 Anti-GBM and ANCA positive pts have a higher relapse risk and require maintenance immunosuppressive treatment ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf190/825758118 Sep 2025 20:15 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lz563vhrc22rhttps://bsky.app/profile/hjanders.bsky.social/post/3lyx5viafak2mNow open access in @ndt-era.bsky.social Comparing CKD populations with T1D and T2D based on FINE-ONE and FIDELITY populations 🧐Similarities between populations may inform the translation of clinical evidence on finerenone from CKD and T2D to CKD and T1D. ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf183/825165916 Sep 2025 10:55 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lyx5viafak2mhttps://bsky.app/profile/hjanders.bsky.social/post/3lyruq2awcs2pNow open access in @ndt-era.bsky.social al CKD of unexplained cause (CKDx): A consensus statement by the Genes &Kidney Working Group of the ERA 🧐Check also our 2 open access editorials on this innovative concept. ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf092/815588014 Sep 2025 08:28 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lyruq2awcs2phttps://bsky.app/profile/hjanders.bsky.social/post/3lymr7s4vak24Now online in @ndt-era.bsky.social Transition of pts with hereditary nephropathies from pediatric to adult care from WG Genes&Kidney of ERA and ESPN 🧐To improve health outcomes, pt empowerment, and engagement for young people with CKD. ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf186/825063712 Sep 2025 07:42 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lymr7s4vak24https://bsky.app/profile/hjanders.bsky.social/post/3lymqixq2lc2uNew RCT online in @ndt-era.bsky.social Additive Effects of Oral Calcitriol on pts with IgAN receiving RAS Blockade 🧐The addition of 0.25 μg/d calcitriol to RASi safely lowered residual proteinuria and slowed eGFR decline in pts with IgAN ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf187/825168712 Sep 2025 07:29 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lymqixq2lc2uhttps://bsky.app/profile/hjanders.bsky.social/post/3lydxlpqpwc2kNow open access in @ndt-era.bsky.social Protein profiles and associated biological pathways among different etiologies of CKD: new insights from DAPA-CKD 🧐Distinct proteomic differences unravel the heterogeneous pathophysiology of human CKD. ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf180/824929008 Sep 2025 19:42 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lydxlpqpwc2khttps://bsky.app/profile/hjanders.bsky.social/post/3lwj6jjz3r22gNow online in @ndt-era.bsky.social Cost-effectiveness of protein restricted diets in advanced CKD 🧐In pts adherent to diet prescription, low-protein diets delay the start of dialysis, improve survival, and save money ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf154/823634916 Aug 2025 10:39 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lwj6jjz3r22ghttps://bsky.app/profile/hjanders.bsky.social/post/3lwis7hjox22nNow open access in @ndt-era.bsky.social Anti-nephrin, anti-podocin and anti-Kirrel1 antibodies: Biological challenges and clinical implications 🧐 Clinical implementation of anti-slit diaphragm antibody testing = precision dx and tx in podocytopathies ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf156/823634616 Aug 2025 06:59 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lwis7hjox22nhttps://bsky.app/profile/hjanders.bsky.social/post/3lwbf5m4ehc23Now open access in @ndt-era.bsky.social What do RCTs teach us about the pathophysiology of human IgAN? 🧐B cells/PC produce the IgAN antigen GdIgA1 as well as the respective autoantibodies, hence targeting B cells/PC will be most clever. ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf144/823266713 Aug 2025 08:16 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lwbf5m4ehc23https://bsky.app/profile/hjanders.bsky.social/post/3lw6la6kjj22jNow online in @ndt-era.bsky.social Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease 🧐Triple-positive pts (anti-type IV collagen, -laminin 521, and -perlecan) = highest prevalence of lung hemorrhage and ESKD ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf153/823098812 Aug 2025 05:27 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lw6la6kjj22jhttps://bsky.app/profile/hjanders.bsky.social/post/3lw4h3hhyhk2wNow open access in @ndt-era.bsky.social Evolving strategies for early diagnosis, proactive prevention and treatment of CKD 🧐"Inferior doctors provide KRT Mediocre doctors treat CKD Superior doctors prevent kidney disease" ▶️ https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf151/822847911 Aug 2025 09:08 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3lw4h3hhyhk2whttps://bsky.app/profile/hjanders.bsky.social/post/3ltth55j7c22eNow online in @ndt-era.bsky.social Acute post-streptococcal GN (in children) - treatment standard 🧐 Pathophysiology, diagnosis, outcome prediction, and management standard ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf130/819789013 Jul 2025 08:24 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3ltth55j7c22ehttps://bsky.app/profile/hjanders.bsky.social/post/3ltqti7uwls2fNow online in @ndt-era.bsky.social Multifactorial chronic kidney disease 🧐 Life is long and our kidneys have to take many hits, hence, adult CKD is usually multifactorial as is atherosclerosis or dementia. RF control is key and RF vary across world regions ▶️ https://academic.oup.com/ndt/article-abstract/doi/10.1093/ndt/gfaf122/818594312 Jul 2025 07:27 +0000at://did:plc:2og3fsjwpbr4trb3uzxtfpqf/app.bsky.feed.post/3ltqti7uwls2f