Highlighting scientific articles published in Carcinogenesis: Integrative Cancer Research - an Oxford University Press journal https://academic.oup.com/carcinhttps://bsky.app/profile/carcin-oxfunipress.bsky.socialhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mtazz76pgk2hA new review article discusses the ATP-gated P2X7 receptor; an example where protein structure-function alteration in cancer cells favors cell survival, by conversion of the cytolytic macropore functional form to a macropore-deficient P2X7 form. https://doi.org/10.1093/carcin/bgag05017 Aug 2026 06:08 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mtazz76pgk2hhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mrmk4jb4tk2cWnt/β-catenin Signaling in Hepatocellular Carcinoma: A Major Context-Dependent Contributor to Resistance to Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors https://doi.org/10.1093/carcin/bgag04027 Jul 2026 09:05 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mrmk4jb4tk2chttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mqocofiwyk24Call for Special Issue Proposals Carcinogenesis invites proposals for special issues that highlight emerging areas of cancer research and integrate discoveries across molecular, cellular, translational, and population sciences. https://academic.oup.com/carcin/pages/call-for-special-issue-proposals15 Jul 2026 08:32 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mqocofiwyk24https://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mq4rzu24b22vChildren with congenital heart disease undergoing cardiac catheterization show changes in circulating microRNAs linked to cancer-related pathways. These may relate to radiation exposure, but their biological significance and health implications remain unclear. https://doi.org/10.1093/carcin/bgag03208 Jul 2026 09:19 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mq4rzu24b22vhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mozxm4fc2c2zNovel mechanism of carcinogenesis mediated by genome deletions induced by high-LET carbon ions https://doi.org/10.1093/carcin/bgag02524 Jun 2026 12:55 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mozxm4fc2c2zhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mm4jhfgb222dAsbestos drives cancer-like traits via mitochondrial outer membrane permeabilization & drug-tolerant persister behaviour https://doi.org/10.1093/carcin/bgag03018 May 2026 09:04 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mm4jhfgb222dhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mj2ama54bc2gThe carcinogenicity of e-cigarettes https://doi.org/10.1093/carcin/bgag01509 Apr 2026 07:05 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mj2ama54bc2ghttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mhfnlae35c2gCarD-T: an automated pipeline for the nomination and analysis of potential human carcinogens https://doi.org/10.1093/carcin/bgaf07419 Mar 2026 09:06 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mhfnlae35c2ghttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mgrkt5k4m22zIn Carcinogenesis: The Tumour Microenvironment in Paediatric Rhabdomyosarcomas https://doi.org/10.1093/carcin/bgag01111 Mar 2026 09:24 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mgrkt5k4m22zhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mgm62vgypc2pNew review article in Carcinogenesis: Functional significance of the aryl hydrocarbon receptor in oncogenic signaling pathways. https://doi.org/10.1093/carcin/bgaf06809 Mar 2026 05:52 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mgm62vgypc2phttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3me64mtelc22pAssociation between survival of patients with colon cancer and tumour infiltrating immune cell density, linked to smoking but not to alcohol consumption. In Carcinogenesis lnkd.in/gnNc9t4p06 Feb 2026 04:58 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3me64mtelc22phttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mdhy7nd3vc2qUranium mining and lung cancer: a legacy of the nuclear age: reviews the long and ongoing story of lung cancer among miners of uranium and other ores exposed to radon and its progeny, which come from the decay of uranium. https://doi.org/10.1093/carcin/bgaf05728 Jan 2026 09:41 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mdhy7nd3vc2qhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3mdhxzp7f6k2qGenomic and transcriptomic characterization of gamma ray– and heavy ion–induced precursor B-cell lymphomas https://doi.org/10.1093/carcin/bgag00228 Jan 2026 09:38 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3mdhxzp7f6k2qhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3ma6fjiraus2jThe passing of Philip Leslie Grover on Sep 1, 2025, aged 91, marks the loss of a foundational figure in carcinogenesis. He was the architect of the diol-epoxide theory, the bedrock of understanding how Polycyclic Aromatic Hydrocarbons bind to DNA, and cause cancer. https://doi.org/10.1093/carcin/bgaf08917 Dec 2025 09:57 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3ma6fjiraus2jhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3ma6edu6no22jTumor-associated astrocytes inhibit tumor cell apoptosis through TNF-α-TNF receptor 2-NF-κB pathway in lung cancer brain metastasis https://doi.org/10.1093/carcin/bgaf09017 Dec 2025 09:36 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3ma6edu6no22jhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m6ykggrqsk22Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring https://doi.org/10.1093/carcin/bgaf04702 Dec 2025 08:43 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m6ykggrqsk22https://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m6t3qgliik2tSummary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958–2009 Carcinogenesis: https://doi.org/10.1093/carcin/bgaf060 #cancer #incidence #atomic #bomb #radiation #Hiroshima #Nagasaki30 Nov 2025 04:37 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m6t3qgliik2thttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m6t3vzlhg22tGenomic landscape of radiation-induced somatic mutations in a normal cell https://doi.org/10.1093/carcin/bgaf04430 Nov 2025 04:40 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m6t3vzlhg22thttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m6t3vzlhg22tGenomic landscape of radiation-induced somatic mutations in a normal cell https://doi.org/10.1093/carcin/bgaf04430 Nov 2025 04:40 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m6t3vzlhg22thttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m6t3qgliik2tSummary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958–2009 Carcinogenesis: https://doi.org/10.1093/carcin/bgaf060 #cancer #incidence #atomic #bomb #radiation #Hiroshima #Nagasaki30 Nov 2025 04:37 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m6t3qgliik2thttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m5desd7wic2dEighty years of cancer research after the atomic bombings of Hiroshima and Nagasaki https://doi.org/10.1093/carcin/bgaf07111 Nov 2025 05:12 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m5desd7wic2dhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m5delujv322dONLINE NOW: Special Issue on Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima and Nagasaki https://academic.oup.com/carcin/issue/46/311 Nov 2025 05:08 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m5delujv322dhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3m3fj7itpd22qAlmonertinib enhances radiosensitivity in EGFR-mutant NSCLC via inhibition of EGFR signaling and DNA damage repair https://doi.org/10.1093/carcin/bgaf07017 Oct 2025 14:46 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3m3fj7itpd22qhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lykjyzwowc2eThe Oncogenic Role of Aurora kinase A in Gastric Cancer: Mechanisms, Pathways and Clinical Relevance https://doi.org/10.1093/carcin/bgaf05411 Sep 2025 10:28 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lykjyzwowc2ehttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lyfjsyxhds2hEpithelial Ikkβ deletion modulates immune responses and the IFNγ/CXCL9 axis during early esophageal carcinogenesis https://doi.org/10.1093/carcin/bgaf05509 Sep 2025 10:41 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lyfjsyxhds2hhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lycneb6phc2lNobel laureate, molecular biologist & cancer researcher, David Baltimore, died at he age of 87. shorturl.at/2t7Ya In 1975, he shared the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, challenging the view that genetic information was only transferred from DNA to RNA08 Sep 2025 07:06 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lycneb6phc2lhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lyclbxdd6k2lΔ133-p53 isoform enhances TLR4 function to promote tumour growth https://doi.org/10.1093/carcin/bgaf05108 Sep 2025 06:29 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lyclbxdd6k2lhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lyckvibqa22lMammary Adipose Dysfunction in the Dual Epidemic of Obesity and Breast Cancer https://doi.org/10.1093/carcin/bgaf05308 Sep 2025 06:22 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lyckvibqa22lhttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lw6mjnd3uc2wRadiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima & Nagasaki In September, Carcinogenesis will publish a special issue to commemorate the 80th anniversary of the atomic bombings in Japan, & our understanding of radiation & its impact on human health academic.oup.com/carcin12 Aug 2025 05:50 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lw6mjnd3uc2whttps://bsky.app/profile/carcin-oxfunipress.bsky.social/post/3lvl3fitgw22wLongitudinal single-cell RNA model aids prediction of EGFR-TKI resistance https://doi.org/10.1093/carcin/bgaf038 The article finds that the molecular mechanisms driving EGFR-TKI resistance in lung cancer may also contribute to poorer prognosis, particularly in lung adenocarcinomas with high EGFR mutation rates.04 Aug 2025 11:23 +0000at://did:plc:4cetvhstyknrenzbnffaff7u/app.bsky.feed.post/3lvl3fitgw22w