We work on the development of “smart” fluorescent probes, improving fluorescence imaging, biosensors and image analysis software. Account managed by lab members. More on https://peterdedecker.be/.https://bsky.app/profile/dedeckerlab.bsky.socialhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3m7mp3jl5gc2kExcited to share our latest work! We introduce FRET-SOFI, a new method for super-resolved imaging of molecular interactions. By combining SOFI with FRET, we achieve subdiffraction resolution in live cells using standard wide-field microscopy. https://pubs.acs.org/doi/10.1021/acs.nanolett.5c0438010 Dec 2025 09:00 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3m7mp3jl5gc2khttps://bsky.app/profile/dedeckerlab.bsky.social/post/3m4dkqsxan226New preprint! Our work together with @agtebo.bsky.social : our 'NanoBlocks' strategy to generate fluorescent biosensors from binders such as nanobodies. Proof-of-concept sensors with ALFA nanobody & Erbin PDZ domain shows the concept in vitro, in cells, and for FACS. https://www.biorxiv.org/cgi/content/short/2025.10.28.685015v129 Oct 2025 13:33 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3m4dkqsxan226https://bsky.app/profile/dedeckerlab.bsky.social/post/3lrswyercwc2qWe are at Innovative Imaging for 3D Cell Biology Conference in #Utrecht. Come to talk to us! 😉 conference.imagine-microscopy.nl/programme17 Jun 2025 16:45 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lrswyercwc2qhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lrswyercwc2qWe are at Innovative Imaging for 3D Cell Biology Conference in #Utrecht. Come to talk to us! 😉 conference.imagine-microscopy.nl/programme17 Jun 2025 16:45 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lrswyercwc2qhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lnihnuey3c2jIt was 3D Fluorescence Imaging Inauguration Day today! 🥳 Together with the lab of Wim Vandenberg, we organized a launch event of two advanced custom-built 3D fluorescence microscopes! 🔬 🔺Triscan: by @robinvde.bsky.social (tinyurl.com/5t3r6x6k) 🔺Single-Objective Light-Sheet (SOLS) by Sergey Abakumov23 Apr 2025 15:03 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lnihnuey3c2jhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3li57267ers2xWe are very happy that Solène Lefebvre was awarded #MSCA Postdoc Fellowship to work in our lab! 🥳🎉 Congratz, great to have you! Results 2024 call: tinyurl.com/5n972ks4 #fellowship #noteasy #postdoc14 Feb 2025 12:24 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3li57267ers2xhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lg66fhu4w22qFor our annual Project Design Contest - postdoc, the winner is Solène Lefebvre with "STaRS = Smart Targeting and Release System" to improve drug delivery and development process. Congratulations! 🥳🏆 #winner #projectdesign20 Jan 2025 10:54 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lg66fhu4w22qhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lfmkho62pc2jSilke Denis is the winner of our annual Project Design Contest - PhD, with her “FPpace” project for fast continuous directed evolution of fluorescent proteins! 🏆 Congrats! 🥳 #winner #projectdesign13 Jan 2025 10:42 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lfmkho62pc2jhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lcwzvv63v22dBig congratulations to our postdoc Robin for being awarded the Science and Innovation Award from the KU Leuven Faculty of Science! 🥳 Well-deserved, not only for work on the TriScan and the Circulator;) @robinvde.bsky.social #scienceaward Picture courtesy: The Image Zone, Johan Van Droogenbroeck.10 Dec 2024 10:30 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lcwzvv63v22dhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lckjznuzqs2qHappy fluo Sinterklaas to everyone! 🙂🥳 mOrange, mScarlet and mCitrine in bacteria ... and mOranges to eat. #fluorescence #sinterklaas05 Dec 2024 11:14 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lckjznuzqs2qhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4dlo4v327🚨Recently, we also published the 'Resonator', which provides quasi-simultaneous fluorescence imaging with multiple excitation wavelengths: Check it out: 👇https://pubs.acs.org/doi/10.1021/acs.nanolett.4c0025809 Sep 2024 09:25 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4dlo4v327https://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4dj2w2v2zVery happy to share the 'Circulator' paper, which is now out in @naturemethods ! 🥳 👉https://rdcu.be/dTa4v Together with @vandenberglab! https://twitter.com/naturemethods/status/183209535842543663609 Sep 2024 09:20 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4dj2w2v2zhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4de3m2q2vLeuven Advanced Microscopy Symposium 2024 was great ! 🔬💫 Thanks to you ! #LAMS2024 @stiel_lab @VoschLab @vandenberglab @Bodeeen1 @JamesDManton @LazarLab @mueller_physics @wmarkbates @michellefrei13 @SusanSuperRes @Fluo_renzo @LReinkensmeier @huserlab @NielsRadmacher23 Aug 2024 12:09 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4de3m2q2vhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4dar6dc2tWe have several positions open in our lab ! 📢🥳 Check our tweet feed ! https://t.co/o8373NMxfF10 Jun 2024 10:55 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4dar6dc2thttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4d64ljy2pAnd we have also a PhD (or potentially postdoc) position OPEN! 📢 Do you want to develop new biosensors for live-cell imaging ? 🦠🔬 Then join our team in the @DedeckerLab ! You can apply till 30/07/2024 ! 🤩👉 https://shorturl.at/KcTYO10 Jun 2024 10:48 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4d64ljy2phttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4d2rwih2vPostdoc position OPEN! 📢 Do you want to develop new molecular biosensors for high content imaging ? 🔬 Then join our team in the @DedeckerLab ! You can apply till 30/07/2024 ! 🥳👉 https://shorturl.at/ZrrkL10 Jun 2024 10:12 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4d2rwih2vhttps://bsky.app/profile/dedeckerlab.bsky.social/post/3lba4cwrhmd2mMaster Thesis Projects Fair was a success! 🤩🧬 Hope to see some of the students we met yesterday in the 24'-25' year! Thanks @KULeuvenChemie for the support! @kuleuven_fwet @vandenberglab #findyourstudent #sciencefair22 Feb 2024 07:57 +0000at://did:plc:4josh6atprafltlrvuqfour5/app.bsky.feed.post/3lba4cwrhmd2m