Structural biology lab at METU and TARLA, managed by Burak V. Kabasakal #structuralbiology #proteindynamics #crystallography #cryoEM previously at Bristol, Imperial, UCDavis, Hacettepe https://bvklab.wixsite.com/bvklabhttps://bsky.app/profile/bvklab.bsky.socialhttps://bsky.app/profile/bvklab.bsky.social/post/3mk72qzfwos2uIn Nottingham, UK for the CCP-EM @ccpem.bsky.social Meeting to catch up with the EM community, hear about the latest developments in the field and exciting research, and tell about our Cryo-EM journey.23 Apr 2026 22:29 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3mk72qzfwos2uhttps://bsky.app/profile/bvklab.bsky.social/post/3mjk5fw7je22cOur cryo-EM analysis of the FtsH periplasmic domain is now published! This study reveals a previously uncharacterized conformational change in the periplasmic domain, suggesting a potential role in substrate translocation. Congratulations to the team! https://pubs.acs.org/doi/10.1021/acschembio.5c0102515 Apr 2026 14:50 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3mjk5fw7je22chttps://bsky.app/profile/bvklab.bsky.social/post/3mj27p6uotk2pRecent paper from our lab! [contains quote post or other embedded content]09 Apr 2026 06:49 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3mj27p6uotk2phttps://bsky.app/profile/bvklab.bsky.social/post/3mi7fw76l7k2gHappy to share that this work from my postdoctoral studies has been published, in which we introduce a robust virus like particle (VLP) platform, ADDomer toward vaccine development applications. Congratulations to Bergers Lab team members! @bristolbiodesign.bsky.social https://pubs.acs.org/doi/10.1021/acssynbio.5c0075729 Mar 2026 14:58 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3mi7fw76l7k2ghttps://bsky.app/profile/bvklab.bsky.social/post/3mey6vp3sac2oBvK LaB is ready to do exciting science in our new place with a great team! 🧫🧪⚛️16 Feb 2026 13:48 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3mey6vp3sac2ohttps://bsky.app/profile/bvklab.bsky.social/post/3mey6oshpf22oBvK LaB was at DESY, Hamburg, Germany DESY for a workshop: Bio-SAXS Beamline at SESAME | Synchrotron-light for Experimental Science and Applications in the Middle East, held in early Februrary, with full of scientific discussions, inspirations, and networking16 Feb 2026 13:45 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3mey6oshpf22ohttps://bsky.app/profile/bvklab.bsky.social/post/3lxjnbbcb7s2dStructural biology was on the stage in the beginning of COVID with the spike protein structures on TV screens now the stage is yours mitochondria [contains quote post or other embedded content]29 Aug 2025 08:28 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lxjnbbcb7s2dhttps://bsky.app/profile/bvklab.bsky.social/post/3lxhmxxcs722gThis morning, I wandered around the medical suppliers and tried to find a piece for our project, then I improvised something with the materials we had on hand-so, if you're solution-oriented and take ownership of your work, you solve it.. I hope you don't lose your excitement for doing science!28 Aug 2025 13:17 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lxhmxxcs722ghttps://bsky.app/profile/bvklab.bsky.social/post/3lvgws4nkdc2bJust returned from an incredible visit to South Korea as part of our bilateral scientific project between Türkiye and Korea! with Seoul National University, funded by TÜBİTAK. I had the privilege of visiting several leading research institutions, IBS, KAIST, KBSI, and Chungnam National University02 Aug 2025 19:50 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lvgws4nkdc2bhttps://bsky.app/profile/bvklab.bsky.social/post/3ltsn5lxqic2qBvK LaB group picture 2025 from the traditional Lake Eymir, Ankara walk. This year, two members graduated as MSc and PhD. Two students, one MSc and one PhD, have joined. Two interns have completed their internship. We are excited for the new term full of science!13 Jul 2025 00:39 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3ltsn5lxqic2qhttps://bsky.app/profile/bvklab.bsky.social/post/3lqllrozxxc2eArnA and AcrB were copurified and structurally resolved within the cryo-EM sample of the overexpressed membrane protein complex, FtsH and YidC. Our study reveals interesting findings and confirms the power of #cryoEM technique. https://www.biorxiv.org/content/10.1101/2025.05.31.656883v102 Jun 2025 01:10 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lqllrozxxc2ehttps://bsky.app/profile/bvklab.bsky.social/post/3lql3qqqzcc2xIn Baltimore, Maryland for #ASMS25 to present our XL-MS studies, explore exciting research in mass spectrometry, and meet great scientists from all over the world.01 Jun 2025 20:23 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lql3qqqzcc2xhttps://bsky.app/profile/bvklab.bsky.social/post/3lq547e7ajs2sI will be at Baltimore, MD, US next week for #ASMS2025 to present XL-MS data of YidC interactions with other partners involved in the bacterial membrane biogenesis and quality control, a part of our TÜBİTAK 2232 project. Please find our poster at #TP659 on Tuesday27 May 2025 06:54 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lq547e7ajs2shttps://bsky.app/profile/bvklab.bsky.social/post/3lpto2aqjl22qMehmet's first first-author publication! A comprehensive review on YidC, its evolution and structure, membrane protein biosynthesis and quality control https://www.sciencedirect.com/science/article/pii/S016748892500061823 May 2025 12:47 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lpto2aqjl22qhttps://bsky.app/profile/bvklab.bsky.social/post/3lptnqw5mqc2qNature News @nature.com mentioned about our latest research on FeSII, related to recently published two nitrogenase-FeSII structures https://www.nature.com/articles/d41586-024-04108-423 May 2025 12:42 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lptnqw5mqc2qhttps://bsky.app/profile/bvklab.bsky.social/post/3lptnmfdrjs2qShethna protein II (FeSII), known as a conformational protector of nitrogenase against oxygen has a swapped domain in the crystal structure. Our study opens a window of new aspect in nitrogenase research https://journals.iucr.org/d/issues/2024/08/00/rr5241/index.html23 May 2025 12:39 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lptnmfdrjs2qhttps://bsky.app/profile/bvklab.bsky.social/post/3lptn7nesqk2jMass spectrometry based structural elucidation of a bacterial mega membrane protein complex involved in quality control. Our study also gives a complete workflow for XL-MS analysis from either purified protein or cell membrane by using 5 different commonly used XL-MS software #xl-ms #proteomics https://www.sciencedirect.com/science/article/pii/S014181302402728423 May 2025 12:32 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lptn7nesqk2jhttps://bsky.app/profile/bvklab.bsky.social/post/3lptmu2mub22jDynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction #carbonfixation #proteindynamics #proteincrystallography https://www.sciencedirect.com/science/article/pii/S030090842300304823 May 2025 12:26 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lptmu2mub22jhttps://bsky.app/profile/bvklab.bsky.social/post/3lptmlutnx22j"State of the art and developments in Cryo-EM sample preparation methods for macromolecular machines" described in our book chapter #cryo-em #structuralbiology #membraneproteins #proteinstructure https://link.springer.com/chapter/10.1007/978-3-031-52193-5_1223 May 2025 12:21 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lptmlutnx22jhttps://bsky.app/profile/bvklab.bsky.social/post/3lptmdgceqk2jOur book chapter where we comprehensively explain sample preparation methods for proteomics analyses in various matrices https://www.sciencedirect.com/science/article/pii/B978044315978700082523 May 2025 12:16 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lptmdgceqk2jhttps://bsky.app/profile/bvklab.bsky.social/post/3lpoqdhw3l222We are now on @bsky.app please find us with the same name @bvklab.bsky.social as in x.com/bvk_lab https://x.com/bvk_lab21 May 2025 13:45 +0000at://did:plc:4xwdgprodwuluecooatjbg7f/app.bsky.feed.post/3lpoqdhw3l222