Biologist by training, basketball player at heart Professor for Translational Epigenetics & Genome Architecture, University Medical Center Goettingen, Germany. www.papantonislab.eu https://bsky.app/profile/akispapantonis.bsky.socialhttps://bsky.app/profile/akispapantonis.bsky.social/post/3mlpwdserik2pOur preprint on how variant U1 snRNAs control transcriptional and splicing homeostasis of hiPSCs is now officially out in @natcomms.nature.com and accessible via this link: https://www.nature.com/articles/s41467-026-73121-0 This has been the culmination of our work as part of the SPP1935 program funded by @dfg.de 1/n [contains quote post or other embedded content]13 May 2026 08:50 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3mlpwdserik2phttps://bsky.app/profile/akispapantonis.bsky.social/post/3mcwcwomcos2fPreprint alert! 🥸 Yajie Zhu (PhD graduate) and Mariano Barbieri (postdoc, @spp2202.bsky.social Accelerator award) produced a package that will classify loops in your #3Dgenomics data based on (whichever) epigenomic data you have available. Keep reading... 1/n https://www.biorxiv.org/content/10.64898/2026.01.13.699359v121 Jan 2026 09:05 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3mcwcwomcos2fhttps://bsky.app/profile/akispapantonis.bsky.social/post/3matolwpi6222Our Xmas present all wrapped and nicely packaged, a collab with @karsten-rippe.bsky.social lab within the realm of the @spp2202.bsky.social [contains quote post or other embedded content]25 Dec 2025 21:05 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3matolwpi6222https://bsky.app/profile/akispapantonis.bsky.social/post/3m7ptycf36s2gAs 2025 comes to a close, I am realising that it has been 20(!) years since the publication of the very first article featuring me as a co-author…11 Dec 2025 15:06 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3m7ptycf36s2ghttps://bsky.app/profile/akispapantonis.bsky.social/post/3m5ggofbk322rLast day of the @spp2202.bsky.social Closing Retreat in Goettingen ending in a high note with Stavros Lomvardas discussing the peculiar 3D attributes of the OR chromatin landscape!12 Nov 2025 10:23 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3m5ggofbk322rhttps://bsky.app/profile/akispapantonis.bsky.social/post/3m5ectgqczc27@karsten-rippe.bsky.social rocking down memory lane and along single cell genomics data in Day 2 of the @spp2202.bsky.social Closing Retreat in Goettingen!11 Nov 2025 14:09 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3m5ectgqczc27https://bsky.app/profile/akispapantonis.bsky.social/post/3m5bupbsk6s2eThe Closing Scientific Retreat of @spp2202.bsky.social is under way in Goettingen with Gerd Blobel delivering the first Keynote lecture on LDB11-mediated looping of chromatin.10 Nov 2025 14:51 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3m5bupbsk6s2ehttps://bsky.app/profile/akispapantonis.bsky.social/post/3m3hnbzy3bk23Science-peripheral post (ignore unless you read in Greek or French): I was surprised and truly honored to receive the Aix-Marseille Metropolitain for the French translation of my novel ‘The last bear of the woods’ (Kichli 2023)—a great thanks to my translators M. Volkich and H. Zervas.18 Oct 2025 11:04 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3m3hnbzy3bk23https://bsky.app/profile/akispapantonis.bsky.social/post/3lzndnacllc2lJust half a day in and it’s been a blast, with really incredible talks here on Giessen! [contains quote post or other embedded content]25 Sep 2025 06:37 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3lzndnacllc2lhttps://bsky.app/profile/akispapantonis.bsky.social/post/3lywvw4kenk25In our latest preprinted work, Yajie and Kostas combine computational analysis with precision KO of single variant U1 snRNA genes in human iPSCs to find pronounced deregulation of both gene expression and splicing that seem to affect the cell cycle and the differentiation potency of stem cells. 1/n16 Sep 2025 08:33 +0000at://did:plc:53ptrfgk7vm44bnd65nsb4ca/app.bsky.feed.post/3lywvw4kenk25