A weekly podcast that focuses on recent Ketamine research. Subscribe on your favorite platform: https://pod.link/1784108044https://bsky.app/profile/talkingketamine.comhttps://bsky.app/profile/talkingketamine.com/post/3mkb63vxx722dCan an anesthetic directly attack cancer cells? 🔬🧬🧪 Ep 60 explores a wild 2026 study showing ketamine triggering "cellular suicide" (apoptosis) in colorectal cancer cells. * Breaking down tumor defenses * Stopping cell division #Ketamine #CancerResearch https://talkingketamine.com/ketamine-vs-colorectal-cancer/ https://youtu.be/mTIBM5eJz4c24 Apr 2026 18:34 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mkb63vxx722dhttps://bsky.app/profile/talkingketamine.com/post/3mimxt7rr5s2yNow with video! youtu.be/4op2z7X6y4U [contains quote post or other embedded content]04 Apr 2026 00:23 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mimxt7rr5s2yhttps://bsky.app/profile/talkingketamine.com/post/3mik6nwtboc2uCan a drug that makes you "space out" actually repair brain damage? 🧠⚡️ Ep 59 explores a 2026 review on ketamine as a cognitive enhancer. 🧯 The "Fire Extinguisher": Stopping toxic excitotoxicity. 🌱 The "Fertilizer": Rebuilding neural pathways (BDNF). 🎧 #Ketamine #Neurology https://talkingketamine.com/ketamine-the-cognitive-enhancer/02 Apr 2026 21:48 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mik6nwtboc2uhttps://bsky.app/profile/talkingketamine.com/post/3mi4zafn6o22rNow with video: youtu.be/YsM_0qkHNPY [contains quote post or other embedded content]28 Mar 2026 16:06 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mi4zafn6o22rhttps://bsky.app/profile/talkingketamine.com/post/3mhymg3kzoc2rAre standard antidepressants turning down the volume on your joy? Ep 58 explores "emotional blunting" vs. ketamine's ability to structurally repair the brain's reward circuits. ** The Engine & The Steering Wheel ** fMRI proof of returning pleasure 🎧 #Ketamine #Neuroscience https://talkingketamine.com/ketamine-and-joy/26 Mar 2026 22:06 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mhymg3kzoc2rhttps://bsky.app/profile/talkingketamine.com/post/3mho3gv5uik2jNow with video! youtu.be/4t0QqPgo-uQ [contains quote post or other embedded content]22 Mar 2026 17:35 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mho3gv5uik2jhttps://bsky.app/profile/talkingketamine.com/post/3mhjhmqt6ek26Big Pharma tried to engineer the "trip" out of ketamine... and accidentally removed the cure. Ep 57 explores the "Gamma-Delta Shift." Gamma waves = the "forest fire" (the trip). Delta waves = the structural regrowth. You can't have the repair without the fire. 🎧 #Ketamine #Neuroscience https://talkingketamine.com/ketamines-brainwave-fingerprint/20 Mar 2026 21:30 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mhjhmqt6ek26https://bsky.app/profile/talkingketamine.com/post/3mgxxv5d3a22bNow with video: youtu.be/33MdYNL4iOY [contains quote post or other embedded content]13 Mar 2026 22:33 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mgxxv5d3a22bhttps://bsky.app/profile/talkingketamine.com/post/3mgvexlesek2gWhat if your ketamine pill isn't actually ketamine by the time it hits your brain? 💊🧠 Ep 56 explores the "liver tollbooth" and how a hidden metabolite drives the therapeutic high. Why oral dosing needs a major math upgrade. 🎧 https://talkingketamine.com/ketamines-child/ #Ketamine #Pharmacology12 Mar 2026 21:49 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mgvexlesek2ghttps://bsky.app/profile/talkingketamine.com/post/3mgqlf57di22rNow with video. youtu.be/X1tlY_MG5-Q [contains quote post or other embedded content]11 Mar 2026 00:01 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mgqlf57di22rhttps://bsky.app/profile/talkingketamine.com/post/3mggo37je5s2pTreating bipolar depression is a trap: standard meds can trigger severe mania. 🎢 Ep 55 explores how ketamine & esketamine change the game: 📉 Rapid relief in hours. 🛑 ZERO manic switches in real-world data. 🧠 Targeting anhedonia. 🎧 #Ketamine #Bipolar https://talkingketamine.com/ketamines-bipolar-balancing-act/07 Mar 2026 01:22 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mggo37je5s2phttps://bsky.app/profile/talkingketamine.com/post/3mfrxokpafs2eDoes anesthesia actually turn your brain off? 🧠💤 Ep 54 explores a terrifying 2026 paper: 🔇 The "Broken Speaker": Paralysis isn't unconsciousness. 🖐️ The Isolated Forearm Technique. 🌀 How ketamine proves the mind expands when the body shuts down. 🎧 #Neuroscience #Ketamine #Anesthesia #Consciousness https://talkingketamine.com/ketamine-proof-of-consciousness/26 Feb 2026 19:48 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mfrxokpafs2ehttps://bsky.app/profile/talkingketamine.com/post/3metju46ma22sWhy does ketamine stop working? It might be your liver. 📉💊 Ep 52 reviews 9 years of ketamine research including "Auto-induction": how the body learns to eat the drug before it reaches your brain. Now with video: 📺 youtu.be/NVObfq0o0gI #Ketamine #Pharmacology #MentalHealth #Science https://youtu.be/NVObfq0o0gI14 Feb 2026 17:21 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3metju46ma22shttps://bsky.app/profile/talkingketamine.com/post/3meoyogtqcs2yWhy does ketamine stop working? It might be your liver. 📉💊 Ep 52 reviews 9 years of research on ketamine including how the body learns to eat the drug before it reaches your brain. Also, Ketamine "softens the clay," but you have to sculpt it. #Ketamine #Pharmacology #MentalHealth #Science https://talkingketamine.com/the-nine-year-odyssey/12 Feb 2026 22:03 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3meoyogtqcs2yhttps://bsky.app/profile/talkingketamine.com/post/3me5ea5i47k22Spravato ($$$) vs. Generic Ketamine ($) A 2026 study compares the FDA-approved giant vs. the compounded generic. 📉 Symptom relief? Identical. ✅ Result: Generic is "non-inferior." 💸 The main difference is the price tag. Ep 51: Why "new" ≠ "improved." #Ketamine #MentalHealth https://talkingketamine.com/the-nasal-spray-wars/05 Feb 2026 21:42 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3me5ea5i47k22https://bsky.app/profile/talkingketamine.com/post/3mdlz7k6jtc27Ketamine goes nanoscopic! Forget the "chemical soup", the synapse is a high-precision machine. - The "Nanocolumn" - The "Ghost" signal that ketamine fixes - How your brain uses "liquid physics" to heal It's all in Episode 50 #Ketamine #Neuroscience #MentalHealth https://talkingketamine.com/ketamine-and-the-nanoscopic-world/30 Jan 2026 00:09 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mdlz7k6jtc27https://bsky.app/profile/talkingketamine.com/post/3mcin3fqu522cKetamine & Diabetes: A metabolic tightrope? It targets the pain/depression "syndemic", but risks are high: Blood sugar spikes & drops; Liver "traffic jams"; Metformin interference? We explore precision Ketamine dosing in Ep 48. #Ketamine #Diabetes https://talkingketamine.com/ketamine-and-diabetes/15 Jan 2026 22:29 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mcin3fqu522chttps://bsky.app/profile/talkingketamine.com/post/3mbwvtobs6k2dWhat does ketamine therapy actually feel like? We move beyond symptom scores to the "Patient's Voice." We explore the "Rollercoaster" of the trip, why staff support is 50% of the cure, and the grief of the crash. #Ketamine #MentalHealth #PatientExperience #Depression https://talkingketamine.com/the-patients-voice/08 Jan 2026 21:18 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mbwvtobs6k2dhttps://bsky.app/profile/talkingketamine.com/post/3mbrwqratis2qIs the "trip" the cure? 😵‍💫 A 2025 review suggests dissociation isn't a side effect—it's key to breaking depressive loops. We explore the "Science of Dissociation" & why chaos in the brain helps. #Ketamine #Neuroscience #MentalHealth https://talkingketamine.com/the-science-of-dissociation/06 Jan 2026 21:51 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3mbrwqratis2qhttps://bsky.app/profile/talkingketamine.com/post/3maegd37mhs2xIs ketamine a "reset button" or a "relational tool"? Ep 45 explores how DOSE defines the therapy: High Dose: Rapid "Psychedelic" reset & ego dissolution. Low Dose: "Psycholytic" safety & deep relational work. https://talkingketamine.com/ketamine-reimagined/ #Ketamine #MentalHealth #Psychedelics19 Dec 2025 19:27 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3maegd37mhs2xhttps://bsky.app/profile/talkingketamine.com/post/3m7r3e6dfhk2cNew study on 74,000 admissions: Early ketamine for kids with Sickle Cell Disease pain crises cut hospital stays in HALF (12 days ➡️ 6 days). 📉 Why is adoption still so low? We break down the data and the barriers. 🎧 https://talkingketamine.com/ketamine-and-sickle-cell-disease/ #SickleCell #Ketamine #PainMgmt12 Dec 2025 02:50 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3m7r3e6dfhk2chttps://bsky.app/profile/talkingketamine.com/post/3m7bdnmilsu2j"Will ketamine work for me?" 🤔 We analyzed a thesis of 112 studies: ❌ Age, sex & trauma don't predict results. ✅ A tiny 4.1% symptom drop after dose 2 signaled 100% success. Full breakdown in Ep 43 🎧 https://talkingketamine.com/will-ketamine-work-for-me/ #Ketamine #MentalHealth #Depression05 Dec 2025 20:36 +0000at://did:plc:5odisx65j4fwkbyhtdmv55ct/app.bsky.feed.post/3m7bdnmilsu2j