Underrated opportunities in science, technology, and society This is an automated Substack Account of https://sarahconstantin.substack.com Discover more/Create at: @skystack.xyzhttps://bsky.app/profile/sarahconstantin.skystack.xyzhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3mhcrpzo6322zFW26 Color Stats • here we go again https://sarahconstantin.substack.com/p/fw26-color-stats14 Mar 2026 15:44 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3mhcrpzo6322zhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3mhcrpzwmlc2zThings that Go Boom • we don't have enough of them https://sarahconstantin.substack.com/p/things-that-go-boom13 Mar 2026 18:53 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3mhcrpzwmlc2zhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3mfsehj44xs2rGetting Back To It • personal update and miscellany https://sarahconstantin.substack.com/p/getting-back-to-it26 Feb 2026 20:26 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3mfsehj44xs2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3me5asi5ofs2rBiotech Startup Stats • What predicts success or failure? https://sarahconstantin.substack.com/p/biotech-startup-stats05 Feb 2026 18:37 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3me5asi5ofs2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3md4kltxpyk2rCancer-Selective, Pan-Essential Targets from DepMap • A Claude Code experiment https://sarahconstantin.substack.com/p/cancer-selective-pan-essential-targets09 Jan 2026 20:35 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3md4kltxpyk2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3mbwtuush5k2rSelf-Help Tactics That Are Working For Me • A little navel-gazing, as a treat https://sarahconstantin.substack.com/p/self-help-tactics-that-are-working08 Jan 2026 17:58 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3mbwtuush5k2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3ma5cwvhcb22rMeasuring Drug Target Success • A data analysis experiment https://sarahconstantin.substack.com/p/measuring-drug-target-success16 Dec 2025 20:59 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3ma5cwvhcb22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vrbjz22rMaking Sense of Consciousness Part 8: Summing Up • What did we learn with all this? https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-f1426 Nov 2025 18:40 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vrbjz22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vrhy2s2rMaking Sense of Consciousness Part 7: Volition • When do we perceive actions as our own? https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-14424 Nov 2025 22:49 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vrhy2s2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vrnuk22rSS26 Color Stats • It's that time of year again https://sarahconstantin.substack.com/p/ss26-color-stats14 Oct 2025 17:10 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vrnuk22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vrtia22rMaking Sense of Consciousness Part 6: Perceptions of Disembodiment • What makes us feel like we're "in our own body" vs not? https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-8a803 Oct 2025 20:32 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vrtia22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vrzepc2rMaking Sense of Consciousness Part 5: Consciousness and the Self • The sense of an "I" https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-bc425 Sep 2025 21:03 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vrzepc2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vsabfs2rI Vibecoded a Dispute Resolution App • What I learned from noodling around with Claude https://sarahconstantin.substack.com/p/i-vibecoded-a-dispute-resolution15 Sep 2025 19:55 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vsabfs2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vsfyys2rMaking Sense of Consciousness Part 4: States of Consciousness • waking, sleeping, anaesthesia, coma, and other "states of consciousness" https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-86108 Aug 2025 21:08 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vsfyys2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vsn6ik2rMaking Sense of Consciousness Part 3: The Pulvinar Nucleus • a neuroscience shaggy dog story https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-40814 Jul 2025 21:16 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vsn6ik2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vstsfs2rMaking Sense of Consciousness Part 2: Attention • The difference between what we notice and what we don't https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part-f5903 Jul 2025 21:12 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vstsfs2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vt33sk2rMaking Sense of Consciousness Part 1: Perceptual Awareness • a noob reads neuro https://sarahconstantin.substack.com/p/making-sense-of-consciousness-part25 Jun 2025 21:03 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vt33sk2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vtd7l22rTech for Thinking • who's working on it? and seriously, can we come up with a better name? https://sarahconstantin.substack.com/p/tech-for-thinking23 Jun 2025 19:15 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vtd7l22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vtr2wk2rBroad-Spectrum Cancer Treatments • A proposal for a research program https://sarahconstantin.substack.com/p/broad-spectrum-cancer-treatments03 Jun 2025 19:30 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vtr2wk2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vtwzec2rWho's Working On It? AI-Controlled Experiments • A real "AI Scientist" would generate new data https://sarahconstantin.substack.com/p/whos-working-on-it-ai-controlled25 Apr 2025 21:34 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vtwzec2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vuf7hk2rThe Uses of Complacency • The optimal amount of self-satisfaction is not zero https://sarahconstantin.substack.com/p/the-uses-of-complacency21 Apr 2025 18:44 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vuf7hk2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vunrus2rProdromes and Biomarkers in Chronic Disease • Can we treat the "untreatable" by catching it before it's diagnosed? https://sarahconstantin.substack.com/p/prodromes-and-biomarkers-in-chronic16 Apr 2025 21:24 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vunrus2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vusww22rFW25 Color Stats • Another season, another reason, for counting colors https://sarahconstantin.substack.com/p/fw25-color-stats25 Mar 2025 18:36 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vusww22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vv25f22rAI "Deep Research" Tools Reviewed • How do they stack up? https://sarahconstantin.substack.com/p/ai-deep-research-tools-reviewed24 Mar 2025 18:35 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vv25f22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vvahjs2rBook Review: Affective Neuroscience • What rats can tell us about feelings https://sarahconstantin.substack.com/p/book-review-affective-neuroscience10 Mar 2025 06:41 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vvahjs2rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vvgxk22rWhat's Behind the SynBio Bust? • And what lessons can we learn? https://sarahconstantin.substack.com/p/whats-behind-the-synbio-bust30 Jan 2025 22:22 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vvgxk22rhttps://bsky.app/profile/sarahconstantin.skystack.xyz/post/3m6o6vwddqk2rWhat Goes Without Saying • a little rant https://sarahconstantin.substack.com/p/what-goes-without-saying20 Dec 2024 17:52 +0000at://did:plc:5og2aybg7ydipfj3h3raqoav/app.bsky.feed.post/3m6o6vwddqk2r