Precision Biophysics and Neurosciencehttps://bsky.app/profile/jorggrandl.bsky.socialhttps://bsky.app/profile/jorggrandl.bsky.social/post/3mgavyquzd22zBeautiful new work on the force-gated ion channel Piezo2. [contains quote post or other embedded content]04 Mar 2026 18:28 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3mgavyquzd22zhttps://bsky.app/profile/jorggrandl.bsky.social/post/3mf57rhb7qk25"Here, we measure the sensitivity of the force-gated ion channel Piezo2 and demonstrate that it is modulated by alternative splicing." New preprint: https://www.biorxiv.org/content/10.64898/2026.02.16.706133v118 Feb 2026 13:47 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3mf57rhb7qk25https://bsky.app/profile/jorggrandl.bsky.social/post/3llohflgmsc2r📣 📣 📣 Optically Guided Tension Clamp 📣 📣 📣 Now out: Michael Sindoni developed a new system that uses machine learning & closed-loop control to clamp membrane tension with high precision. Study your favorite force-gated ion channel! #IonChannel #Biophysics Read more: https://www.cell.com/biophysj/fulltext/S0006-3495(25)00199-731 Mar 2025 13:24 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3llohflgmsc2rhttps://bsky.app/profile/jorggrandl.bsky.social/post/3lhbuf23q5226Our lab will be presenting 1 talk at 3 posters at the upcoming Biophysical Society Annual Meeting. If you are attending we would love to connect with you and show our work: 1) A CLOSED-LOOP SYSTEM FOR MILLISECOND READOUT AND CONTROL OF MEMBRANE TENSION. Poster B284. Monday, Feb 17 1:45 PM03 Feb 2025 15:31 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3lhbuf23q5226https://bsky.app/profile/jorggrandl.bsky.social/post/3lgbcx3q3qs2rTo catch up, I recently had the opportunity to give a seminar at Johns Hopkins - Neuroscience. How much fun to meet my former Scripps Chair Uli Mueller and @ardemp.bskyverified.social postdoc colleague Zhaozhu Qiu, and make new friends Alex Kolodkin, Edward Twomey, and Xinzhong Dong.21 Jan 2025 16:54 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3lgbcx3q3qs2rhttps://bsky.app/profile/jorggrandl.bsky.social/post/3lg6nwscamd2vExcited to join Bluesky today! As an ion channel biophysicist, Professor at Duke Neurobiology, and Director of Graduate Studies I will be sharing my insights. Plus the occasional post of my private life. Please help me connect to my community by sharing this post.20 Jan 2025 15:32 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3lg6nwscamd2vhttps://bsky.app/profile/jorggrandl.bsky.social/post/3lg6jzjt4td2vFollow the work of the Grandl Lab: sites.duke.edu/grandllab/20 Jan 2025 14:22 +0000at://did:plc:7preqo7g4qzv7col5q44xio4/app.bsky.feed.post/3lg6jzjt4td2v