Wistar is the nation's first independent biomedical research center. We focus on cancer, infectious disease & vaccine research to benefit human health.https://bsky.app/profile/wistar.orghttps://bsky.app/profile/wistar.org/post/3mp7jkuwqys2wCould a single injection replace weekly weight loss shots? Wistar scientists developed a single-dose DNA method that manages weight and blood glucose 10x longer than current therapies in preclinical models. Read more: bit.ly/4oL7w1C #obesity #diabetes #weightloss #biotech #Wistar26 Jun 2026 18:00 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mp7jkuwqys2whttps://bsky.app/profile/wistar.org/post/3mnzijfa2ns2yThanks to GEN for highlighting Dr. Katherine Aird’s new @nature.com paper revealing how ovarian cancer cells use a metabolic trick to resist chemotherapy — and how blocking it could restore treatment sensitivity. 🔬 This could change the game for patients with hard-to-treat tumors. bit.ly/4x5iPpr11 Jun 2026 15:00 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mnzijfa2ns2yhttps://bsky.app/profile/wistar.org/post/3mnfed6udhx2hStay connected to the latest discoveries at Wistar! Sign up for Wistar News to get research breakthroughs, inspiring stories, and updates on the people and projects advancing biomedical science in Philadelphia and beyond. Sign up today: www.wistar.org/news-sign-up/03 Jun 2026 14:52 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mnfed6udhx2hhttps://bsky.app/profile/wistar.org/post/3mgxbpvombc2sDon't miss out! Join us next Wednesday, 3/18, for the Philadelphia Drug Discovery Forum! Join Mallika Singh, Ph.D., of Revolution Medicines for her talk, “Targeting the Oncogenic State of RAS.” 🕞 Doors open: 3:30 PM 🕓 Talk begins promptly: 4 PM 🥂 Networking: 5 PM 👉 Register now! bit.ly/4qQkg6B13 Mar 2026 15:57 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mgxbpvombc2shttps://bsky.app/profile/wistar.org/post/3mdyd2f4cw22tWistar scientists have developed a vaccine strategy that induced neutralizing antibodies with a single shot in a preclinical study—a first-ever achievement. Led by Dr. Amelia Escolano, this breakthrough could lead to simpler, faster, and cheaper vaccination protocols globally. bit.ly/4ceGGdY https://www.wistar.org/press-releases/wistar-scientists-demonstrate-first-ever-single-shothiv-vaccine-neutralization-success/03 Feb 2026 21:37 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mdyd2f4cw22thttps://bsky.app/profile/wistar.org/post/3mczlh4nlzk2gThanks to our speakers Dr. Jason DeHart and Dr. Jason Lamontagne and everyone who joined the latest Philadelphia Drug Discovery Forum! Want to connect with Philly’s biopharma community? Join the next PDDF on March 18, 4–6 p.m. Learn more: bit.ly/4bcdm7B22 Jan 2026 16:15 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mczlh4nlzk2ghttps://bsky.app/profile/wistar.org/post/3mck7sutq5k22🚨 Last chance to register! Join us Jan 21, 4–6 p.m. at The Wistar Institute for the Philadelphia Drug Discovery Forum. Hear from leaders in biopharma and connect with peers shaping the future of medicine. Register: bit.ly/4hQgasj16 Jan 2026 13:37 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mck7sutq5k22https://bsky.app/profile/wistar.org/post/3mcicf65xgc2uCongrats to Dr. Italo Tempera on his promotion to Professor! After postdoc training in Wistar's Lieberman lab, he launched his own lab at Temple before returning to Wistar in 2020. Since then, he's published in top‑tier journals and had major grant success. 👏 Congrats! bit.ly/49mwnTv https://bit.ly/49mwnTv15 Jan 2026 19:18 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3mcicf65xgc2uhttps://bsky.app/profile/wistar.org/post/3lw7hbo7rzs2wHear from Federica Severi, a pre-doctoral trainee in Dr. Dan Claiborne's lab, about her work researching CAR T cells as a therapy against HIV. “What we do here is immunotherapy, where we make the immune system more powerful against infection … like HIV”12 Aug 2025 13:49 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lw7hbo7rzs2whttps://bsky.app/profile/wistar.org/post/3lrazjftchc25Hear from Wistar predoctoral fellow Maya Foster about what fuels her passion for science. "I work with actual cancer cells -- we do actual cancer research. Our work is quite important."10 Jun 2025 13:42 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lrazjftchc25https://bsky.app/profile/wistar.org/post/3lqsb5q6pzs2lWistar was proud to host Life Science Cares Philadelphia for a tour! As a valued partner, they support our work to expand access to life science careers for those in HS, college and beyond.04 Jun 2025 16:49 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lqsb5q6pzs2lhttps://bsky.app/profile/wistar.org/post/3lpkcekhfp22qThe American Society of Gene + Cell Therapy Annual Meeting was an amazing opportunity for Wistar scientists Drs. Patel, Gary and Parzych, & predoc Nick Tursi, in the lab of Dr. David Weiner, to share their important research on such a huge stage!19 May 2025 19:24 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lpkcekhfp22qhttps://bsky.app/profile/wistar.org/post/3lo6xyksncs2wWe’re excited to welcome Dr. Xiaoyu Zhou as assistant professor in Wistar’s Vaccine & Immunotherapy Center! Her cutting-edge work in immune cell communication & CAR T-cell engineering is a great addition to Wistar’s collaborative work advancing cancer & infectious disease therapies. bit.ly/4iLDypU02 May 2025 13:54 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lo6xyksncs2whttps://bsky.app/profile/wistar.org/post/3lmrzlos6v22yIn a new collaborative paper from Wistar’s Salvino lab, the Penn Perelman School of Medicine, and the University of Leeds, published in Nature Structural & Molecular Biology, researchers have discovered a new molecular glue that combats dysregulated inflammatory signaling: bit.ly/4lf941M14 Apr 2025 16:53 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lmrzlos6v22yhttps://bsky.app/profile/wistar.org/post/3lloybd63ok22Three Wistar trainees were recently recognized for excellence in science. Dr. Ignacio Rodriguez Relano received the 2024 Ching Jer Chern Postdoctoral Fellowship, while Drs. Phillip Wulfridge & Brennah Murphy Britten received the 2024 & 2025 Ching Jer Chern Memorial Awards. Congratulations!31 Mar 2025 18:26 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lloybd63ok22https://bsky.app/profile/wistar.org/post/3llekwcmdhk2vThanks to the Justamere Foundation for awarding Wistar’s Hubert J.P. Schoemaker Education and Training Center a 2-year, $150K grant. The grant supports Wistar’s BTT for ALL in PHL Program that helps residents of Philadelphia train for secure jobs in the region’s thriving biomedical sector.27 Mar 2025 15:00 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3llekwcmdhk2vhttps://bsky.app/profile/wistar.org/post/3ll4yvjvl6c2qOn World TB Day, we shine a light on the deadliest infectious disease in the world. Caused by Mycobacterium tuberculosis, it has been around for centuries and has been tracked in the U.S. since the 1950s. Learn more about this disease and why it’s making a resurgence now: bit.ly/4iAX6ho24 Mar 2025 14:49 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3ll4yvjvl6c2qhttps://bsky.app/profile/wistar.org/post/3lklfv6o5522cWistar recently unveiled 2 new internal grants that will provide valuable funding opportunities to early-career researchers to foster collaborations & eventually establish independent research programs: bit.ly/4bV9zK8 https://bit.ly/4bV9zK817 Mar 2025 14:54 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lklfv6o5522chttps://bsky.app/profile/wistar.org/post/3lkbdnma5ls27Wistar's Dr. Kristy Shuda McGuire strongly believes, “To learn science, you need to do science.” She comes from a long line of teachers & has her hand on the pulse of the latest training needed for next-gen science careers. Learn more: bit.ly/4iJaDD6 https://bit.ly/4iJaDD613 Mar 2025 14:47 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lkbdnma5ls27https://bsky.app/profile/wistar.org/post/3ljifxfln222nTriple-negative breast cancer is a difficult-to-treat cancer that affects 10-15% of breast cancer patients in the U.S., defined by the absence of 3 receptors: estrogen, progesterone, and HER2. Continued cancer research is essential to overcoming this challenge. #triplenegativebreastcancerday03 Mar 2025 16:52 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3ljifxfln222nhttps://bsky.app/profile/wistar.org/post/3ljawhsp2rc2zWistar is pleased to announce the recruitment of its newest faculty member, Dr. Colby Maldini, to the HIV Cure and Viral Diseases Center. The Maldini lab will expand his work on CAR T cells as part of a strategy to cure HIV and other viral threats. bit.ly/4gWzcv2 https://bit.ly/4gWzcv228 Feb 2025 17:26 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3ljawhsp2rc2zhttps://bsky.app/profile/wistar.org/post/3ljavajl2uk2uNew preclinical research from Wistar’s @filippov81.bsky.social published in Cancer Discovery shows how brain cancer reprograms immune cells to work for the cancer rather than against it. Their discovery also enables a potential treatment to disrupt the reprogramming process. bit.ly/4ijBIMT https://bit.ly/4ijBIMT28 Feb 2025 17:04 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3ljavajl2uk2uhttps://bsky.app/profile/wistar.org/post/3ljajukvhkk2kThe Wistar Institute's Montaner lab was pleased to host members of the HIV Advocacy for Cure Academy, who received a tour of the Institute and Dr. Montaner's laboratory facilities where scientists continue their work to seek a cure for HIV.28 Feb 2025 13:41 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3ljajukvhkk2khttps://bsky.app/profile/wistar.org/post/3lj65u4fz4c27Some questions Wistar's EHS head Roma Maraj-Owens thinks about a lot: “What are your experimental procedures? How can we protect our employees and the environment?” Read more about how she ensures institutional safety in her Q&A: bit.ly/41lh0FP https://bit.ly/41lh0FP27 Feb 2025 15:00 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lj65u4fz4c27https://bsky.app/profile/wistar.org/post/3lifbfhm3ik2qIn their second “Top Read” paper in less than a year, Wistar’s Montaner lab has published the successful preclinical results of their new anti-HIV approach: NuKES, or Natural Killer Enhancement Strategy, which targets the viral reservoirs standing in the way of a cure. bit.ly/4hF0UNZ https://bit.ly/4hF0UNZ17 Feb 2025 17:27 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lifbfhm3ik2qhttps://bsky.app/profile/wistar.org/post/3lhyiqmq6q226Many thanks to @jenheemstra.bsky.social of Washington University in St. Louis for joining The Wistar Institute as part of the Distinguished Lectures in Cancer Research series, to speak to the importance of intentional, high-quality mentorship in the sciences. Read more: bit.ly/41ao9d312 Feb 2025 15:34 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lhyiqmq6q226https://bsky.app/profile/wistar.org/post/3lhhczxgpxs2sIn a new paper, Wistar’s Villanueva lab has discovered a new strategy to treat melanomas harboring mutations in the NRAS gene that don’t respond to MAPK inhibitors. Their treatment kills these mutant melanoma cells in preclinical testing with FDA-approved drugs. Our story: bit.ly/411yfwB https://bit.ly/411yfwB05 Feb 2025 19:37 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lhhczxgpxs2shttps://bsky.app/profile/wistar.org/post/3lhgxl4wtbc23Wistar is hiring! Friday 2/7, join us at Temple University's job fair from 11-2 pm at the Howard Gittis Student Center to learn about our openings for postdoctoral fellowships and research assistant roles throughout more than 30 labs. Hope to see you there! No registration required.05 Feb 2025 16:11 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lhgxl4wtbc23https://bsky.app/profile/wistar.org/post/3lhesozrsxs24Thanks to a new research grant from the Melanoma Research Foundation, The Wistar Institute’s Dr. Kazuko Nishikura is embarking on a project she hopes will serve as a proof of concept for a cancer treatment decades in the making. Our story: bit.ly/3WKOtYs https://bit.ly/3WKOtYs04 Feb 2025 19:39 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lhesozrsxs24https://bsky.app/profile/wistar.org/post/3lhbsutskes22Every cancer case starts somewhere, While new treatments are vital, prevention is just as key to protecting health. That’s why researchers at Wistar’s Ellen and Ronald Caplan Cancer Center pursue research to detect risks early & stop cancer in its tracks. #nationalcancerpreventionmonth03 Feb 2025 15:04 +0000at://did:plc:a5pgtwx5wc4kvd55it6qtgrc/app.bsky.feed.post/3lhbsutskes22