Bioengineering, Biophysics, Computational Biology and Molecular and Cell Biology. Account run by students/post-docs. Lab website: https://fletchlab.berkeley.edu/https://bsky.app/profile/fletcherlabucb.bsky.socialhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3mkipoq37ec2oCongratulations to Carlos (@carlosfng.bsky.social) for being a recipient of the 2026 Outstanding Graduate Student Peer Mentor Award. Images courtesy of Laure Andrillon.27 Apr 2026 18:37 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mkipoq37ec2ohttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3mjnethbz5s2nCongratulations Smiti (@smitim.bsky.social) for passing your qualifying exam! #PhDCandidate16 Apr 2026 21:41 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mjnethbz5s2nhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3mjafe3wwh227Join us for the 22nd Fletcher Lab Artshow! We’re looking for artists to submit their work and be part of an evening celebrating creativity and community. We will also have the return of the Ground State Ensemble! Art by @chunzi-liu.bsky.social @qb3-berkeley.bsky.social @berkeleymcb.bsky.social11 Apr 2026 17:46 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mjafe3wwh227https://bsky.app/profile/fletcherlabucb.bsky.social/post/3mijm6oqcuk2qIn our new work published in @natbiomedeng.nature.com in collaboration with @theottlab.bsky.social and @doudna-lab.bsky.social, we introduce "interfering" guide RNAs (igRNA) for CRISPR-Cas13a that regulate enzyme activity after activation. Congrats to all the authors! https://www.nature.com/articles/s41551-026-01642-602 Apr 2026 16:17 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mijm6oqcuk2qhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3mgll6zw7nc23Happy #internationalwomensday to all of the incredible women, especially those from our lab (past and present). Your curiosity, creativity and determination continue to shape our science and community.09 Mar 2026 00:14 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mgll6zw7nc23https://bsky.app/profile/fletcherlabucb.bsky.social/post/3mer4krqebc2mThe NTDscope is a portable brightfield, darkfield, and fluorescence microscope used for diagnosing neglected tropical diseases (NTDs). This video shows S. mansoni miracidia. Check out our most recent publication: https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.000593713 Feb 2026 18:18 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mer4krqebc2mhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3meoqmmrjys2qCheck out our latest preprint: LUCas! A direct light control of Cas13 trans-cleavage activity. Congrats to all the authors: Carlos (@carlosfng.bsky.social), Deepak (@deepakkrish.bsky.social), Andres, and Aymeric. https://www.biorxiv.org/content/10.64898/2026.02.02.700737v112 Feb 2026 19:39 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3meoqmmrjys2qhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3mcg64kjwak2kPreprint out now! Cell surfaces are crowded with tall proteins that block immune recognition. We discovered tall binding proteins create “stepping stones” that help short receptors engage, even in dense crowds. A new design principle for #immunotherapy. In memory of Phillip L. Geissler https://www.biorxiv.org/content/10.64898/2026.01.09.698749v114 Jan 2026 22:56 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3mcg64kjwak2khttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3ma2ptbjvhs2dHow does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work! https://www.nature.com/articles/s41556-025-01807-6 https://www.nature.com/articles/s41556-025-01818-315 Dec 2025 22:51 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3ma2ptbjvhs2dhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3m7djqeht222fIf you are going to #ASCB2025, check out some great talks and posters from our lab members06 Dec 2025 17:30 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3m7djqeht222fhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3m6na6rcc3k27Happy Thanksgiving! Gratitude today for everyone pushing the frontiers of science in their different roles.27 Nov 2025 20:41 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3m6na6rcc3k27https://bsky.app/profile/fletcherlabucb.bsky.social/post/3m6i3tohhq22xCheck out our latest published manuscript: SurFlex microscopy, a new technique to measure molecular flexibility. Congrats to Aymeric, @sid592.bsky.social, @blenackmon.bsky.social, and Andres! https://www.pnas.org/doi/10.1073/pnas.250882812225 Nov 2025 19:40 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3m6i3tohhq22xhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3m3ooj7qfcc2wCongratulations Dan for being elected to the National Academy of Medicine! bit.ly/4o0pDj521 Oct 2025 06:14 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3m3ooj7qfcc2whttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lzgringjbk2wCheck out Siddhansh (@sid592.bsky.social) presentation at the 4th Physics of Life Symposium hosted by the #CZBiohubSF. https://youtu.be/b7G5wyE6iyo?feature=shared22 Sep 2025 15:56 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lzgringjbk2whttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lz2szwp4q22sHappy Postdoc Appreciation Week to all of our postdocs! #PostdocAppreciationWeek17 Sep 2025 21:52 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lz2szwp4q22shttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lxg3v7e2cc2vCongratulations Kira for passing your qualifying exam!27 Aug 2025 22:39 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lxg3v7e2cc2vhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lwcxogsehs2gTake a look at our newest published article in PLOS NTD: https://doi.org/10.1371/journal.pntd.0012879 #schistosomiasis #ML #diagnostics13 Aug 2025 23:20 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lwcxogsehs2ghttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lvrju2job22qCheck out our most recent published paper in @natcomms.nature.com about the effects of cell surface crowding in cell-cell fusion: rdcu.be/ezCOF https://rdcu.be/ezCOF07 Aug 2025 00:58 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lvrju2job22qhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lvo5z7udz22cCheck out this talk by one of our amazing postdocs, Deepak! youtu.be/ErE3f5iyPio https://youtu.be/ErE3f5iyPio05 Aug 2025 16:48 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lvo5z7udz22chttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3luszdgmgs22uHad fun at the MBL Physiology Course in Woods Hole! Chunzi, Elizabeth & Kira led creative rotations: • Trogocytosis is a mi(gh)t-y way to transfer • Sync(ytium) or Swim: Which fusogen will reign supreme? • Mucin Impossible: Eat up or get lost25 Jul 2025 21:42 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3luszdgmgs22uhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lsml25w7nk2iWelcome to our new BioE Ph.D. students, Smiti and Michael Anne! @smitim.bsky.social27 Jun 2025 21:20 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lsml25w7nk2ihttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lrxkcmxcbk2pCongratulations Caitlin!! [contains quote post or other embedded content]19 Jun 2025 12:41 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lrxkcmxcbk2phttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lndy6ekaks2jCome to the Annual Fletcher Lab Artshow on Friday May 9th, 2025! We host this event yearly as an opportunity for folks to display their artwork, come together with wine and cheese, and admire artwork!21 Apr 2025 20:15 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lndy6ekaks2jhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3lmfuzatpbk24Come explore and be amazed on April 12 and 13 at the @exploratorium.bsky.social. This event is based upon work supported by the Center for Cellular Construction. #microscopy #Magnified09 Apr 2025 20:59 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3lmfuzatpbk24https://bsky.app/profile/fletcherlabucb.bsky.social/post/3llrxijbdgk2fCongratulations to both Jared and Andres for passing their qualifying exams01 Apr 2025 22:50 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3llrxijbdgk2fhttps://bsky.app/profile/fletcherlabucb.bsky.social/post/3llhe4gjobk23The NTDscope is a portable brightfield, darkfield, and fluorescence microscope used for the diagnosis of neglected tropical diseases (NTDs). Check out our latest preprint: https://www.medrxiv.org/content/10.1101/2025.03.17.25324136v128 Mar 2025 17:37 +0000at://did:plc:afdjcaxng3lc6f45ylzh7jzc/app.bsky.feed.post/3llhe4gjobk23