Professor of Physiology. Researcher. Like to see where cells are and how they are. Prefer cancer cells dead, and neurones alive and happy. Not afraid of AI.https://bsky.app/profile/profjochen.bsky.socialhttps://bsky.app/profile/profjochen.bsky.social/post/3m6m7rb77nk22Nice collaboration with Susanna Narkilahti’s group at Tampere University now out, showing elevated tRFs in an in vitro hyperexcitation model in iNeurons. @futureneuro.bsky.social @physiologyrcsi.bsky.social https://www.sciencedirect.com/science/article/pii/S030645222501125X?via%3Dihub27 Nov 2025 11:01 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3m6m7rb77nk22https://bsky.app/profile/profjochen.bsky.social/post/3m6m6nbhitk2bA new pipeline for detecting Fusobacterium in WGS datasets from our lab with immunohistochemical confirmation just out. https://www.biorxiv.org/content/10.1101/2025.11.24.690231v127 Nov 2025 10:41 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3m6m6nbhitk2bhttps://bsky.app/profile/profjochen.bsky.social/post/3m6eqfbmfnc2eExcellent collaboration with @annagolebiewska.bsky.social delivering humanised glioblastoma patient-derived xenograft models to test novel immunotherapy strategies for brain cancer. https://www.biorxiv.org/content/10.1101/2025.11.20.689484v124 Nov 2025 11:37 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3m6eqfbmfnc2ehttps://bsky.app/profile/profjochen.bsky.social/post/3lupipdb6422jBig thanks also to Boris Rogelj who acted as extern and gave an excellent talk on RNAs that bind proteins (or was it proteins that bind RNAs 🤔) in ALS and FTD. @physiologyrcsi.bsky.social24 Jul 2025 12:07 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lupipdb6422jhttps://bsky.app/profile/profjochen.bsky.social/post/3lupihhn52s2uCongratulations to Qilian who passed her PhD viva investigating effects of tiRNAs on FUS phase transition in ALS @physiologyrcsi.bsky.social24 Jul 2025 12:02 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lupihhn52s2uhttps://bsky.app/profile/profjochen.bsky.social/post/3lqa3sspv7227Delighted for Prof Annette Byrne @physiologyrcsi.bsky.social to be elected as a member of the Royal Irish Academy yesterday for her achievements on cancer research.28 May 2025 11:25 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lqa3sspv7227https://bsky.app/profile/profjochen.bsky.social/post/3lq6g3aq3z22zCongrats to Batuhan Khisakol and all @physiologyrcsi.bsky.social PhD students who were conferred today!27 May 2025 19:24 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lq6g3aq3z22zhttps://bsky.app/profile/profjochen.bsky.social/post/3lhco7pbfts2cWhen chemotherapy may do harm - super plexing of cell death proteins shows that ‘persister’ cells do not benefit from 5-FU based adjuvant chemotherapy in colon cancer https://bmjoncology.bmj.com/content/3/1/e00036203 Feb 2025 23:13 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lhco7pbfts2chttps://bsky.app/profile/profjochen.bsky.social/post/3lgvtklcq2c22Delighted to chair the ‘Clinical Decision Support Tools’ session at #ICSB2025 in Dublin, Oct 5-9 youtu.be/i8ekr_KmwvA @rcsi.bsky.social @physiologyrcsi.bsky.social @rcsi-research.bsky.social https://youtu.be/i8ekr_KmwvA29 Jan 2025 20:44 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lgvtklcq2c22https://bsky.app/profile/profjochen.bsky.social/post/3lf3j2okits2uWhat are the biological functions of stress-induced tiRNAs (tRNA fragments) - we took an unbiased approach exploring an #ALS associated tiRNA https://www.sciencedirect.com/science/article/pii/S0014488624004540?via%3Dihub @physiologyrcsi.bsky.social @rcsi-research.bsky.social @mndresearch.bsky.social #ncRNA #MND06 Jan 2025 16:02 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lf3j2okits2uhttps://bsky.app/profile/profjochen.bsky.social/post/3ler5ttuvqk2dFocus on 💪 in ALS: We found a new role for Angiogenin in muscle regeneration with diagnostic implications. https://onlinelibrary.wiley.com/doi/10.1111/bpa.13328 @mndresearch.bsky.social @rcsi-research.bsky.social @physiologyrcsi.bsky.social @neuroscienceirl.bsky.social #ALSResearch #MNDResearch02 Jan 2025 13:15 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3ler5ttuvqk2dhttps://bsky.app/profile/profjochen.bsky.social/post/3ldpagd2lt22xDr Batu! - delighted that @researchireland.bsky.social @genomicscrt PhD student Batuhan Kisakol has passed his viva today- with no corrections! Thanks to examiners @sudiptodas_rcsi and @oncode.bsky.social ‘s JP Medema @rcsi-research.bsky.social @physiologyrcsi.bsky.social 🎉👏🏻🍾🎓20 Dec 2024 01:30 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3ldpagd2lt22xhttps://bsky.app/profile/profjochen.bsky.social/post/3lbres2dw6k2fFully funded MSC PhD positions in AI and Parkinson’s Disease now available, including two positions at @rcsi.bsky.social Apply at https://.aipd-dn.eu/en/vacancies.html @rcsi-research.bsky.social25 Nov 2024 11:03 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lbres2dw6k2fhttps://bsky.app/profile/profjochen.bsky.social/post/3lbluem3nak2kCongrats to my former MD student Bill Duggan for the @rcsi.bsky.social Postgraduate School 2024 Clinical Research Award for his @gutmicrobes.bsky.social paper on spatial effects of bacterial infection on the transcriptome in colorectal cancer @rcsi-research.bsky.social @physiologyrcsi.bsky.social23 Nov 2024 06:26 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lbluem3nak2khttps://bsky.app/profile/profjochen.bsky.social/post/3lb7si2za7s2fOur new manuscript is out showing distinct fingerprints of tRNA fragments during neurodegeneration, led by our SFI CRT GDS PhD student Sharada Baindoor. https://doi.org/10.1242/dmm.05087018 Nov 2024 11:20 +0000at://did:plc:asdqs6jhp2h7wtypch2fnmux/app.bsky.feed.post/3lb7si2za7s2f