Official Acct: Dr. Cliff Rosen's group researching the metabolic & biochemical fate of marrow stromal cells as progenitor osteoblasts & adipocytes at MaineHealthhttps://bsky.app/profile/cjrosenlab.bsky.socialhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m7skcu5x4c22We are thrilled to welcome Ruixin Feng, medical student at University of New England, to the Rosen lab! Ruixin has a strong interest in understanding how weight loss impacts bone health and will be working under the guidance of @carolynchlebek.bsky.social.12 Dec 2025 16:51 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m7skcu5x4c22https://bsky.app/profile/cjrosenlab.bsky.social/post/3m7arou6w222cWhat are the mechanisms of weight loss induced bone loss? Check out our recent review of the current literature on the mechanistic pathways and clinical consequences of weight loss–induced bone loss: https://doi.org/10.1038/s41413-025-00483-405 Dec 2025 15:15 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m7arou6w222chttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m76bldmhnc2dHuge congratulations to Dr. Victoria DeMambro, recipient of the 2025 Soft Bones Maher Family Research Grant for hypophosphatasia! This grant will support her research to understand underlying causes of muscle weakness & chronic fatigue symptoms in adult HPP patients lnkd.in/eutXHxNK04 Dec 2025 15:21 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m76bldmhnc2dhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m4qhpyl4mc2lCongratulations to lab member, Linyi Liu, on his recent promotion to Staff Scientist I! 🎉03 Nov 2025 16:43 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m4qhpyl4mc2lhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m4jgimfm6k23Shoutout to our lab manager, Phuong, for representing the Rosen lab in the MHIR Costume Contest and securing first place!! 🥇🎉 [contains quote post or other embedded content]31 Oct 2025 21:33 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m4jgimfm6k23https://bsky.app/profile/cjrosenlab.bsky.social/post/3m4jehxanq223Happy Halloween from the Rosen lab! @demambrove.bsky.social @carolynchlebek.bsky.social31 Oct 2025 20:57 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m4jehxanq223https://bsky.app/profile/cjrosenlab.bsky.social/post/3m4e6ht7qjc2zHow does calorie restriction change the skeleton in obese mice? Check out our latest paper, out now in Bone. Spoiler: calorie restriction leads to bone loss and shifts the metabolome in the cortex! Congratulations, @carolynchlebek.bsky.social https://doi.org/10.1016/j.bone.2025.11769029 Oct 2025 19:26 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m4e6ht7qjc2zhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m4bb3g63422fNew lab photo for the Rosen lab! 📸28 Oct 2025 15:35 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m4bb3g63422fhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m46k7v4zac2dCurious about how weight loss strategies affect bone health in patients with obesity? Check out this recent review article published in #JBMR @asbmr.bsky.social https://doi.org/10.1093/jbmr/zjaf13527 Oct 2025 13:40 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m46k7v4zac2dhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3m3mw6qaz7k2wEarlier this month, medical student Stephanie Lam represented the Rosen lab at the University of New England College of Medicine's Fall Research Forum! Stephanie shared her findings on changes to animal behavior during caloric restriction, generated through her work with @carolynchlebek.bsky.social20 Oct 2025 13:26 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3m3mw6qaz7k2whttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lyvh5iwbck2oWe are excited to have Samuel Rubin continue in our lab as a Research Assistant I! Sam started with us as a part-time learner and is now managing an independent research project - go, Sam! Stay tuned to hear about all his exciting research.15 Sep 2025 18:36 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lyvh5iwbck2ohttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lyb5eeoqxc2hLots of fun at #ASBMR2025! We’re excited for another great day! @asbmr.bsky.social07 Sep 2025 16:47 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lyb5eeoqxc2hhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3ly4kysnq622tHuge congrats to lab member @demambrove.bsky.social on a fantastic talk this morning at #ASBMR2025! 🎉🦴 if you didn’t get a chance to ask your question at the session, be sure to find Dr. DeMambro at this meeting! @asbmr.bsky.social05 Sep 2025 21:08 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3ly4kysnq622thttps://bsky.app/profile/cjrosenlab.bsky.social/post/3ly47t6kdjc2gHuge thanks to @natalieasims.bsky.social for featuring Dr. DeMambro’s abstract during this morning’s session! We are also so excited for this presentation! Join us at noon in Room 6E (TODAY!) #ASBMR2025 @asbmr.bsky.social [contains quote post or other embedded content]05 Sep 2025 17:48 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3ly47t6kdjc2ghttps://bsky.app/profile/cjrosenlab.bsky.social/post/3ly2sgdifss2jPlanning out which amazing @asbmr.bsky.social sessions you want to hit tomorrow? Be sure to go to Room 6E tomorrow at noon to hear about treating adult HPP mice with Ilofotase Alfa from @demambrove.bsky.social! (Abstract #1020) Plus so many other great rare bone talks in this session! 🦴05 Sep 2025 04:16 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3ly2sgdifss2jhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lxzqwl4sa22kAre you at the @asbmr.bsky.social /RBDA Symposium on Rare Bone Diseases? Check out Dr. DeMambro’s poster on Ilofotase Alfa treatment in adult HPP mice, which was recognized by a Pre-Meeting Young Investigator Travel Grant for the top Young Investigators presenting today 🎉04 Sep 2025 18:16 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lxzqwl4sa22khttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lxcv64ht4c2xInterested in the role of bone in whole-body energy metabolism? Check out this recent review in @natrevendo.nature.com ! Co-authored by lab leader, Dr. Cliff Rosen 🦴26 Aug 2025 16:01 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lxcv64ht4c2xhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lwhft7pcok2sProof that beach days are good for #bones!15 Aug 2025 17:44 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lwhft7pcok2shttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lw7tr3i7pc25We love seeing our lab members featured in the MHIR Newsletter! Congrats, again Dr. DeMambro! 🎉12 Aug 2025 17:32 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lw7tr3i7pc25https://bsky.app/profile/cjrosenlab.bsky.social/post/3luofdlobhc2hWe are SO excited that Dr. Victoria DeMambro successfully defended her PhD 🎉 Dr. DeMambro’s thesis, entitled “Tissue Nonspecific Alkaline Phosphatase: more than a pro-mineralizing enzyme”, focused on hypophosphatasia 🦴24 Jul 2025 01:34 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3luofdlobhc2hhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3ltkg37ubn22xWe are SO excited to welcome Dr. Madhura Nijsure @madhura0327.bsky.social to the Rosen lab this week! As a postdoc, she is excited to explore how diet and nutrition influence bone health and homeostasis at the molecular level. Stay tuned for her amazing research!09 Jul 2025 18:11 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3ltkg37ubn22xhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lstc4pf7d22hCan the new wave of GLP1 medications be useful for treating Type 1 Diabetes? Check out this editorial and the associated articles in the @nejm.org to learn more! https://evidence.nejm.org/doi/abs/10.1056/EVIDe250017830 Jun 2025 13:29 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lstc4pf7d22hhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lslrmplpyc2tLooking for a fun Friday read? Check out our most recent paper exploring the inflammatory responses and lipid metabolism in bone marrow adipocytes after high calorie feeding and fasting in humans! Huge congratulations to Dr. Costa & team for such exciting work! https://doi.org/10.3389/fendo.2025.159128027 Jun 2025 13:45 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lslrmplpyc2thttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lsc7cdy4tk22We are excited to welcome #UNECOM student Stephanie Lam to the Rosen lab! Stephanie will be working with @carolynchlebek.bsky.social to understand the effects of calorie restriction on bone and other organ systems.23 Jun 2025 18:23 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lsc7cdy4tk22https://bsky.app/profile/cjrosenlab.bsky.social/post/3lrv4yhcjuk2lCongratulations to the @asbmr.bsky.social Harold M. Frost Young Investigator Award recipients! We are excited to see our own @carolynchlebek.bsky.social among the awardees 🎉 Attend the @orssociety.bsky.social Musculoskeletal Biology Workshop to hear from the awardees about their exciting research!18 Jun 2025 13:38 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lrv4yhcjuk2lhttps://bsky.app/profile/cjrosenlab.bsky.social/post/3lrqhn6u52s2kLast week, we said goodbye to Dr. Costa, but we cannot wait to hear about her amazing postdoctoral research ahead at the University of Pittsburgh! Congratulations again to Dr. Costa on a fantastic thesis and research career at MaineHealth! You will be missed!16 Jun 2025 17:05 +0000at://did:plc:be7sswlfnh3uvpuhmonp2fi5/app.bsky.feed.post/3lrqhn6u52s2k