BBI takes advantage of Seattle’s culture of collaboration in technology and the health sciences, and its leadership in genomics, bioinformatics, and data science. https://bsky.app/profile/brotmanbaty.bsky.socialhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lxd46dvdwc22BBI's annual Long-Read Sequencing Symposium is set for Sept. 16th, 10 am to 4:30 pm; poster session - 11:45 to 12:50. Location is UW's Foege Hall South, 3720 15th Ave NE, Seattle. Visit Redcap for details/registration; registration ends Sept. 5 at 12 noon. https://redcap.iths.org/surveys/?s=8HWF9DYXT88HAPNR26 Aug 2025 18:06 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lxd46dvdwc22https://bsky.app/profile/brotmanbaty.bsky.social/post/3lrqg2gw7v223POSTDOC ALERT: Applications now open for SeaBridge postdoc fellowship; opportunity to work on leading-edge biotech w/researchers at the Seattle Hub for Synthetic Biology. https://brotmanbaty.org/news/new-postdoc-fellowship-program-builds-on-innovative-seattlehub-research @marionpepper.bsky.social @jshendure.bsky.social @coletrapnell.bsky.social16 Jun 2025 16:36 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lrqg2gw7v223https://bsky.app/profile/brotmanbaty.bsky.social/post/3lqvbugil6s2bZachary Amador, left, scientist w/Seattle Hub for Synthetic Biology, explains to artist Ranger Liu an experiment using DNA - they are collaborating togther in the Fred Hutch SxAffold "encounter" this week among artists & scientists. @fredhutch.bsky.social @calliechappell.bsky.social05 Jun 2025 21:40 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lqvbugil6s2bhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lqq2rztgsk2fRanger Liu, artist & physicist working on a Ph.D. in Astronomy at UW, is working w/a SeattleHub researcher as part of SxAffold, the weeklong collaboration among scientists & artists at the Hutch. Photo by Connor O’Shaughnessy / Fred Hutch https://alleninstitute.org/division/seattle-hub-for-synthetic-biology/ @fredhutch.bsky.social03 Jun 2025 19:50 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lqq2rztgsk2fhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lqn3bydby22qTOMORROW - June 3 - at 9 AM - The Variant Effects Seminar Series will feature Ben Li (U of Michigan) & Vahid Aslanzadeh (U of Edinburgh) Details: https://www.varianteffect.org/seminar-series/ @varianteffect.bsky.social @uwmedicine.bsky.social02 Jun 2025 15:21 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lqn3bydby22qhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lprq7x4fpc2oMS 2025 Update: @cwjpugh.bsky.social presents on 'Breaking the Scaling Barrier in Protein Variant Effect Prediction." @jonnyfrazer.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @varianteffect.bsky.social @fritzroth.bsky.social @muffley.bsky.social #VariantEffect25 https://bsky.app/profile/did:plc:7mb66niixxzuojirdcqvb4hh22 May 2025 18:21 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lprq7x4fpc2ohttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lpox7kbimk2yUpdate from MSS 2025 in Barcelona: Dave Adams of Wellcome-Sanger presents on how genetic variation impacts cancer disease risk. Photo: Jonathan Frazer @jonnyfrazer.bsky.social @varianteffect.bsky.social @davidjadams.bsky.social @lindorfflarsen.bsky.social @sangerinstitute.bsky.social21 May 2025 15:48 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lpox7kbimk2yhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lpmfzhdqx22wMSS 2025 is underway in Barcelona. Many thanks to Jonathan Frazier for posting updates regularly. Several BBI researchers are participating. @jonnyfrazer.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @muffley.bsky.social @shawnfayer.bsky.social #VariantEffect2520 May 2025 15:35 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lpmfzhdqx22whttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lpcfwquuls2e'Science can feel like magic. When you begin to understand how and why things work, it’s incredible.' Learn more about Katie Partington, an 'intellectually adventurous' promising young scientist in the lab of BBI's Dr. Doug Fowler. https://brotmanbaty.org/news/promising-young-scientist-for-katie-partington-science-can-be-like-magic @dougfowler.bsky.social @hmc.edu16 May 2025 16:07 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lpcfwquuls2ehttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lpaeim2rkc2fNew paper by UW Medicine's Colin Pritchard clears up confusion on treating ‘passenger’ vs. ‘driver’ mutations in BRCA1 and 2 genes. Learn more. https://ascopubs.org/doi/pdf/10.1200/PO-25-00141 @uwmedicine.bsky.social @ascocancer.bsky.social15 May 2025 20:36 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lpaeim2rkc2fhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lp5s53wehs2hHi Jonathan, we at BBI are looking forward to your posts next week from MSS 2025 from Barcelona. Cheers! @jonnyfrazer.bsky.social @varianteffect.bsky.social @bennibolo.bsky.social #VariantEffects2514 May 2025 20:02 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lp5s53wehs2hhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lp2xrgtgq22yHUGE congrats Lara Muffley - honored w/ UW Distinguished Staff Award for Collaboration - advancing world-class research on genetic variants on behalf of BBI https://brotmanbaty.org/news/bbis-lara-muffley-receives-uws-distinguished-staff-award-for-collaboration @varianteffect.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @mehurles.bsky.social13 May 2025 17:05 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lp2xrgtgq22yhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3loowov6nlk2pAre you or someone you know affected by Hemophilia B? BBI's Drs. Jill Johnsen & Doug Fowler have advanced genetic understandinng of the blood disorder. Learn more. https://brotmanbaty.org/news/new-mutational-scanning-method-advances-genetic-understanding-of-hemophilia @uwmedicine.bsky.social @dougfowler.bsky.social @hemophilia.bsky.social08 May 2025 22:13 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3loowov6nlk2phttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lo7vmdlt2c22AI & Precision Medicine: The Stuart and Molly Sloan Precision Oncology Institute at Fred Hutch Cancer Center is hosting a symposium on AI, on Tuesday, May 20. Learn how AI is shaping treatment, diagnosis & prevention strategies for cancer. @fredhutch.bsky.social https://www.fredhutch.org/en/events/stuart-and-molly-sloan-precision-oncology-institute-ai-symposium.html02 May 2025 22:44 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lo7vmdlt2c22https://bsky.app/profile/brotmanbaty.bsky.social/post/3lo54reqyoc22Next up for the Variant Effects Seminar Series: Tuesday, 6 May, 9am (Pacific) w/ Timothy Tan (U of Illinois) & Mustafa Tekpinar (Van Yüzüncü Yıl University). Details: https://www.varianteffect.org/seminar-series/ @uwgenome.bsky.social @varianteffect.bsky.social01 May 2025 20:14 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lo54reqyoc22https://bsky.app/profile/brotmanbaty.bsky.social/post/3lnnqi2v3lk2cCheck out the newly refreshed Atlas of Variant Effects website: www.varianteffect.org/for A smoother & more intuitive experience. Kudos to the Wellcome Sanger Webdev team for their work @sangerinstitute.bsky.social25 Apr 2025 17:24 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lnnqi2v3lk2chttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lne6kdbye22lOne never knows the power and persuasion of elementary school teachers. Jonas ("Gus") Gustafson's fifth grade instructor 'allowed me to establish a life-long knack and passion for STEM.’ @uwmedicine.bsky.social @danrdanny.bsky.social https://brotmanbaty.org/news/promising-young-scientist-for-jonas-gustafson-success-combines-interest21 Apr 2025 22:09 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lne6kdbye22lhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lmx4p4ntkk2jNew study in Genome Biology: Guidelines for releasing a variant effect predictor - 'enhance personalized medicine & genetic disease understanding, aligning w/calls for standardized, rigorous VEP practices in genomic medicine' https://genomebiology.biomedcentral.com/articles/10.1186/s13059-025-03572-z @broadinstitute.org16 Apr 2025 17:32 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lmx4p4ntkk2jhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lms2npu2722qLooking Ahead: Mutational Scanning Symposium 2025, May 21-23, Barcelona, features Kresten Lindorff-Larsen addressing interface between variant effects & interpretation. Learn more: https://brotmanbaty.org/news/spotlight-on-mss-2025-lindorff-larsen-to-address-symposium-on-interface @varianteffect.bsky.social @lindorfflarsen.bsky.social @bennibolo.bsky.social14 Apr 2025 17:12 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lms2npu2722qhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lmfiixmgtk2r'The lives of cells, recorded:' Nature perspective reflects foundational principles of Seattle Hub & 'further(s) our understanding of cell decisions over time, given their cellular ancestry & past cell trajectories.' @naturegenet.bsky.social @jshendure.bsky.social https://brotmanbaty.org/news/nature-perspective-reflects-foundational-principles-of-seattle-hub09 Apr 2025 17:15 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lmfiixmgtk2rhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3llovil37q22aTOMORROW - 9 am (Pacific) Variant Effects Seminar - Presentations by Joyce Kang (Harvard-MIT) and Yiyun Rao (Penn State) @broadinstitute.org @pennstateuniv.bsky.social @varianteffect.bsky.social Learn more: www.varianteffect.org/seminar-series31 Mar 2025 17:36 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3llovil37q22ahttps://bsky.app/profile/brotmanbaty.bsky.social/post/3llerf7lfic2dMark your calendars now. The next variant effects seminar is Monday, 1 April, 9 am (Pacific), featuring Joyce Kang @harvard.edu @broadinstitute.org & Yiyun Rao @pennstateuniv.bsky.social. @varianteffect.bsky.social Learn more: www.varianteffect.org/seminar-series27 Mar 2025 16:56 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3llerf7lfic2dhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lktcdfqpgk2xHow do get hired for a position that's "a perfect match" for your professional interests? Read - and be inspired by - Hina Iftikhar's story. @alleninstitute.bsky.social @genentech.bsky.social @chanzuckerberg.bsky.social @uwmedicine.bsky.social https://brotmanbaty.org/news/promising-young-scientist-a-researcher-finds-perfect-match-for-my20 Mar 2025 18:11 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lktcdfqpgk2xhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lkljipbdik2oNew Paper Advances Understanding how Genetic Variations Drive Disease: ‘We were able to resolve genetic & molecular basis of (the patient’s) condition, providing both her family & care team w/ answers to support her moving forward.’ @naturegenet.bsky.social https://brotmanbaty.org/news/paper-advances-understanding-how-genetic-variations-drive-disease-q-and-a17 Mar 2025 15:58 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lkljipbdik2ohttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lk6yyw6cck2m@uwmedicine.bsky.social "Huddle" underscores the importance of the new $10m grant to Seattle Hub https://huddle.uwmedicine.org/10m-awarded-to-advance-cell-and-genome-technologies/ @alleninstitute.bsky.social @chanzuckerberg.bsky.social12 Mar 2025 16:31 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lk6yyw6cck2mhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3lk4nvsk5m22hHow does a young person who loves both science and art decide on a career? Seattle Hub's Dr. Jonas Koeppel has a theory. @alleninstitute.bsky.social @jonaskoeppel.bsky.social @chanzuckerberg.bsky.social @sudpinglay.bsky.social https://brotmanbaty.org/news/promising-young-scientist-jonas-koeppel-overcomes-a-professional-dilemma-and11 Mar 2025 18:07 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3lk4nvsk5m22hhttps://bsky.app/profile/brotmanbaty.bsky.social/post/3ljqcrqsdoc2aThe Washington Research Foundation's $10M, 5-year grant will help move Seattle forward as the 'epicenter of synthetic biology.' @chanzuckerberg.bsky.social @alleninstitute.bsky.social https://brotmanbaty.org/news/washington-research-foundation-awards-usd10m-to-seattle-hub-to-advance-cell06 Mar 2025 20:16 +0000at://did:plc:buv5ebcjgrbmonwr4pos3soo/app.bsky.feed.post/3ljqcrqsdoc2a