Welcome to the Institute for Stroke and Dementia Research (ISD) in Munich – Director: Prof. Martin Dichgans https://www.isd-research.de/https://bsky.app/profile/isd-research.bsky.socialhttps://bsky.app/profile/isd-research.bsky.social/post/3ml6pauyw6s2bThe SFB 1744 / CRC 1744 website is now published www.sfb1744.de 🎊 It not only represents work, events, publications of the CCN in NVD network but furthermore offers a platform for the Graduate Program IRTG-BrainVasc including open PhD positions! www.sfb1744.de/sfb1744 https://www.sfb1744.de/open-positions/c7171d6b0a96d59e06 May 2026 12:28 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3ml6pauyw6s2bhttps://bsky.app/profile/isd-research.bsky.social/post/3mk7y6i5hzs2zAdvanced Clinician Scientist Program for Comprehensive Neuroscience (PROMISE) https://www.med.lmu.de/de/wissenschaftliche-karriere/medical-clinician-scientist-program-mcsp/promise/24 Apr 2026 07:15 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mk7y6i5hzs2zhttps://bsky.app/profile/isd-research.bsky.social/post/3mk643ch2uc2nCRC1744 Launch – Kick-off Event With the official launch of CRC1744 we welcomed principal investigators and early career researchers as well as distinguished guest speakers to a one-day kick-off meeting. https://www.isd-research.de/news/crc1744-launch-kick-off-event/5232af37e568dc9623 Apr 2026 13:20 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mk643ch2uc2nhttps://bsky.app/profile/isd-research.bsky.social/post/3mjz5zmbs7c27A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology | Science Translational Medicine https://www.science.org/eprint/5H5YDPCPFQ3KBUSNE2A7/full?activationRedirect=/doi/full/10.1126/scitranslmed.adu984521 Apr 2026 14:11 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mjz5zmbs7c27https://bsky.app/profile/isd-research.bsky.social/post/3mhfuqvjspk24Biomarkers for advancing diagnosis and prognosis in stroke - https://www.sciencedirect.com/science/article/pii/S147444222500480619 Mar 2026 11:14 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mhfuqvjspk24https://bsky.app/profile/isd-research.bsky.social/post/3mhb3lxnb5c2kISD Investigators have secured major funds from Germany’s Federal Ministry of Research, Technology and Space, to strengthen clinician-led, translational neuroscience research. PROMISE will support 12 competitively selected Advanced Clinician Scientists >> https://www.isd-research.de/scrivito/advanced-clinician-scientist-program-funded/376bce5f7dc549eb17 Mar 2026 13:34 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mhb3lxnb5c2khttps://bsky.app/profile/isd-research.bsky.social/post/3mf746z23s223Image of the Week: Congrats to the team of González-Gallego J et al., Nat Neurosci. 2026 for this lovely award in Nature Briefing 🏆 🖼️ @judit-gonzalez.bsky.social @paquetlab.bsky.social (->Fig 2b https://www.nature.com/articles/s41593-025-02123-w) [contains quote post or other embedded content]19 Feb 2026 07:49 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mf746z23s223https://bsky.app/profile/isd-research.bsky.social/post/3mch4yfknqk2bBrain-derived tau for monitoring brain injury in acute ischemic stroke - Great work by Steffen Tiedt, his team of ISD researchers and international partners now published in Science Translational Medicine: https://www.science.org/doi/10.1126/scitranslmed.adz1280 🎊🙌 #BD-tau #ischemic15 Jan 2026 08:09 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3mch4yfknqk2bhttps://bsky.app/profile/isd-research.bsky.social/post/3m7mf5xaltk2xCongratulations! 🏆 The European Research Council has awarded the prestigious ERC Consolidator Grant to support TRAINED, a project led by Arthur Liesz (ISD) that investigates how maladaptive trained immunity drives systemic inflammation and multimorbidity after stroke and myocardial infarction.10 Dec 2025 06:03 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3m7mf5xaltk2xhttps://bsky.app/profile/isd-research.bsky.social/post/3m6h5l27rdk22German Research Foundation (DFG) has approved funding of a new CRC on “Compartmentalized Cellular Networks in Neurovascular Diseases”. Thanks to everyone involved!🙏 https://www.lmu.de/en/newsroom/news-overview/news/lmu-successful-with-two-collaborative-research-centre-funding-applications.html25 Nov 2025 10:38 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3m6h5l27rdk22https://bsky.app/profile/isd-research.bsky.social/post/3m6h5cbry7c26Synaptic density and tau pathology in Alzheimer’s disease: a dual role in susceptibility and degeneration url: https://academic.oup.com/brain/article-abstract/doi/10.1093/brain/awaf425/832255225 Nov 2025 10:33 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3m6h5cbry7c26https://bsky.app/profile/isd-research.bsky.social/post/3m5iz4wasac2bHappy to find Martin Dichgans on the list of Highly Cited Researchers™ once more 🎉 https://clarivate.com/highly-cited-researchers/13 Nov 2025 10:59 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3m5iz4wasac2bhttps://bsky.app/profile/isd-research.bsky.social/post/3m3mfjssktk2tKey risk factors for post-stroke dementia uncovered: results from DEMDAS study identify metabolic syndrome + reduced HDL cholesterol as novel, modifiable risk factors for post-stroke dementia... https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00220-0/fulltext20 Oct 2025 08:28 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3m3mfjssktk2thttps://bsky.app/profile/isd-research.bsky.social/post/3lyukhwga522rCortical tau deposition promotes atrophy in connected white matter regions in Alzheimer’s disease url: https://academic.oup.com/brain/article-abstract/doi/10.1093/brain/awaf339/8253259 #tao @nfranzme.bsky.social15 Sep 2025 10:03 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lyukhwga522rhttps://bsky.app/profile/isd-research.bsky.social/post/3lyfmzbh6ls2zMarios Georgakis and team showed IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk https://www.nature.com/articles/s44161-025-00700-709 Sep 2025 11:38 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lyfmzbh6ls2zhttps://bsky.app/profile/isd-research.bsky.social/post/3lyfmemy7b22zMikael Simons receives $500,000 for a project to investigate disease mechanisms involving tau proteins. The funding is part of the international program „Tauopathy Challenge Workshop 2025“, supporting research projects aimed at understanding and treating tau-associated diseases such as AD. 🎉09 Sep 2025 11:27 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lyfmemy7b22zhttps://bsky.app/profile/isd-research.bsky.social/post/3ltlxzfass22jAnnual ISD Research Retreat 🎆 Great talks, project presentations, poster session, games, guest talks and an amazing LLM workshop by Rainer Malik 🙏10 Jul 2025 09:05 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3ltlxzfass22jhttps://bsky.app/profile/isd-research.bsky.social/post/3lqmgw5qtec2tArthur Liesz received the prestigious ESO Scientific Excellence Award for his contributions to the understanding of stroke and neurovascular disease. The award was delivered in the Presidential Session at the European Stroke Organisation Conference (ESOC 2025) in Helsinki. @arthurliesz.bsky.social 👏02 Jun 2025 09:16 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lqmgw5qtec2thttps://bsky.app/profile/isd-research.bsky.social/post/3lq5gzw6fds2vThe Munich Cluster for Systems Neurology (SyNergy) has been awarded a third funding period (2026-2032) by the DFG. 🎆 👏 @synergy-munich.bsky.social27 May 2025 10:08 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lq5gzw6fds2vhttps://bsky.app/profile/isd-research.bsky.social/post/3lmr5c3vib22nInterested in cellular mechanisms of cognitive decline after stroke? Check out this work in Nature communications: Anna-Sophia Wahl lab track the fate of individual neurons involved in spatial memory before + after multiple, distributed microstrokes using chronic 2photon imaging in-vivo. 👍 https://rdcu.be/ehm5214 Apr 2025 08:26 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lmr5c3vib22nhttps://bsky.app/profile/isd-research.bsky.social/post/3lmqxmmsld22eFor his research project “Reprogrammed microglial cells as a therapeutic approach against Alzheimer's Disease” Dominik Paquet receives funding from the Alzheimer Forschung Initiative 🙌 @afi-ev.bsky.social https://www.alzheimer-forschung.de/forschung/forschungsprojekte/projektdatenbank/projekt/paquet-2025/14 Apr 2025 06:45 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lmqxmmsld22ehttps://bsky.app/profile/isd-research.bsky.social/post/3lkngub6kas2kAlpha-synuclein co-pathology promotes tau accumulation in Alzheimer’s disease - findings by ISD investigators published in Molecular Neurodegeneration 👏 rdcu.be/ed0Su @nfranzme.bsky.social @springernature.com18 Mar 2025 10:16 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lkngub6kas2khttps://bsky.app/profile/isd-research.bsky.social/post/3lkb2phwnqk22An atypical chemokine that links atherosclerosis and metabolic disease - A new study led by ISD staff identifies D-dopachrome tautomerase (D-DT/MIF-2) as an atypical chemokine that promotes both atherosclerosis and hepatic lipid accumulation. (...) read: 👉 https://www.isd-research.de/scrivito/isd-research-news 👏13 Mar 2025 12:07 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3lkb2phwnqk22https://bsky.app/profile/isd-research.bsky.social/post/3ljpoqiamsc26Finally printed: ISD Annual Report 2023/2024: Nice overview about the last years of research life and events at the institute. Thanks to everyone who contributed.🫶 https://www.isd-research.de/about-us/media-nbsp/79c4060aaa11212d06 Mar 2025 14:18 +0000at://did:plc:cuvsr5hymxp3opu2evyb77tr/app.bsky.feed.post/3ljpoqiamsc26