Assistant Professor at Rutgers New Jersey Medical School | Systems Biology, Synthetic Biology, Machine Learning, Antibiotic Resistance, Tuberculosis, Heart Failure, Immunoengineeringhttps://bsky.app/profile/jasonyanglab.orghttps://bsky.app/profile/jasonyanglab.org/post/3mpluoqtjlc22I'm thrilled to share that the lab has received its first R01!! Together with Shuyi Ma and Christoph Grundner, we will be exploring how M tuberculosis gene networks regulate drug tolerance. More soon, but we will be recruiting postdocs and graduate students!01 Jul 2026 15:51 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3mpluoqtjlc22https://bsky.app/profile/jasonyanglab.org/post/3mkkn54uavk2rAI and synthetic biology are revolutionizing bioengineering. We're now in a time when these technologies are synergizing to create "living" drug delivery vehicles. @bashorlab.bsky.social and I discuss this at Advanced Drug Delivery Reviews: https://www.sciencedirect.com/science/article/pii/S0169409X2600117128 Apr 2026 12:57 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3mkkn54uavk2rhttps://bsky.app/profile/jasonyanglab.org/post/3mgx3jncwf22iHappy to share that my research center at Rutgers NJMS is hiring tenure-track faculty at all ranks! We are broadly interested in infectious disease research from experimental to computational. Please ask questions and join our community! https://jobs.rutgers.edu/postings/13954113 Mar 2026 14:06 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3mgx3jncwf22ihttps://bsky.app/profile/jasonyanglab.org/post/3m22mrletlk2gVery happy to share some more good news. Our collaboration with Jeffrey Boyd's lab is now published at J Inorganic Biochemistry! Here, Jeff found that iron limitation reprograms S. aureus metabolism towards fermentation. We're grateful to be part of this study. https://www.sciencedirect.com/science/article/pii/S016201342500265X?dgcid=coauthor30 Sep 2025 13:25 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3m22mrletlk2ghttps://bsky.app/profile/jasonyanglab.org/post/3lyxkqr7ecc22Happy to share that our collaboration with Christina @stallingslab.bsky.social at WUSTL is out at @pnas.org ! Led by Erin Wang, they found that routing carbon away from peptidoglycans sensitizes Mtb to INH, even in DR-Mtb! Grateful to be part of this project! https://www.pnas.org/doi/abs/10.1073/pnas.242133612216 Sep 2025 14:45 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lyxkqr7ecc22https://bsky.app/profile/jasonyanglab.org/post/3lxsticltys2zI'm pleased to share that the preprint for our collaboration study on MIS-C in pediatric COVID-19 patients is now available on medRxiv. In this study led by Marila Gennaro at Rutgers NJMS, we report that antibody repertories vary with clinical presentation of COVID-19 in children. [contains quote post or other embedded content]02 Sep 2025 00:13 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lxsticltys2zhttps://bsky.app/profile/jasonyanglab.org/post/3lvu5xu52hk2aIt's nearing the end of the summer and our undergrads have been presenting on their research at their respective summer research symposia. Terrific work by Jonah Simone at the Rutgers Health BMIHAI Symposium and Gianna Elie at the NJMS URSE Symposium!08 Aug 2025 02:03 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lvu5xu52hk2ahttps://bsky.app/profile/jasonyanglab.org/post/3lvdjhj5lo225I'm excited to share that we've received a NIBIB Trailblazer Award to advance our work on engineering therapeutic macrophages! Grateful for our team and excited to launch this collaboration with the Caleb @bashorlab.bsky.social at Rice!01 Aug 2025 11:14 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lvdjhj5lo225https://bsky.app/profile/jasonyanglab.org/post/3lvc5qcvwes2dMany thanks to ScienceNews.dk for highlighting our work! https://sciencenews.dk/en/stressed-bacteria-develop-antibiotic-resistance-more-easily31 Jul 2025 22:11 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lvc5qcvwes2dhttps://bsky.app/profile/jasonyanglab.org/post/3lsjubj4uuc2tThank you @njmicrobe.bsky.social for this really nice writeup about our work! [contains quote post or other embedded content]26 Jun 2025 19:27 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lsjubj4uuc2thttps://bsky.app/profile/jasonyanglab.org/post/3lrdhv6pntc2r@rutgersu.bsky.social published a very nice article about our work! https://www.rutgers.edu/news/rutgers-health-research-identifies-new-trigger-accelerating-antibiotic-resistance @njms-mdphd.bsky.social11 Jun 2025 13:05 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lrdhv6pntc2rhttps://bsky.app/profile/jasonyanglab.org/post/3lr73o4vxjk2nI'm thrilled to share the newest paper from the Yang Lab! Ever wonder how bacterial metabolism affects antibiotic resistance #AMR? In this study, Barry Li, a former MD/PhD student in the lab, took on this question using a systems and #synthetic_biology approach. 1/n https://www.nature.com/articles/s41467-025-60302-609 Jun 2025 19:15 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lr73o4vxjk2nhttps://bsky.app/profile/jasonyanglab.org/post/3lp5z7eusts2rHonored to receive this year's Young Investigator Award from our local ASM branch! [contains quote post or other embedded content]14 May 2025 22:08 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lp5z7eusts2rhttps://bsky.app/profile/jasonyanglab.org/post/3lp4y4tyrnk2hYang Lab had a terrific time at Rutgers' Biomedical Health Informatics and Artificial Intelligence Symposium yesterday. Great jobs by Yiqi Yan, Oliver Gu, and Reuven Rosen who presented on their work!14 May 2025 12:16 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lp4y4tyrnk2hhttps://bsky.app/profile/jasonyanglab.org/post/3lohy3wapks2wOur undergraduate machine learning maestro Edson Petry gave a terrific research presentation this afternoon at the Rutgers Pathways for Junior Scientists Research Program! #Rutgers #NJMS06 May 2025 03:50 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lohy3wapks2whttps://bsky.app/profile/jasonyanglab.org/post/3lnlb62tedc2pI'm so proud of my technician Lia Goodwin who presented a poster at her first conference at the CSHL Systems Immunology meeting yesterday!24 Apr 2025 17:45 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lnlb62tedc2phttps://bsky.app/profile/jasonyanglab.org/post/3llwkiqjf3k2sEver wonder how Mycobacterium #tuberculosis deals with stressful environments? I'm pleased to share that in a second piece of good news this week, our recent work in collaboration with Shuyi Ma (Seattle Children's) was published at Frontiers in Tuberculosis. 1/n https://www.frontiersin.org/journals/tuberculosis/articles/10.3389/ftubr.2025.1500899/full03 Apr 2025 18:41 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3llwkiqjf3k2shttps://bsky.app/profile/jasonyanglab.org/post/3lltzembun226I am thrilled to share that our rock star MD/PhD student Barry Li successfully defended his PhD today entitled "Bioenergetic stress potentiates antimicrobial resistance evolution and persistence"! Barry is our first student to finish his PhD and I am so incredibly proud of him!02 Apr 2025 18:29 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lltzembun226https://bsky.app/profile/jasonyanglab.org/post/3lcfwfggqjk2nPleased to share our papers are highlighted by the editors at Nature Communications: https://www.nature.com/collections/jedgcgeija03 Dec 2024 15:12 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lcfwfggqjk2nhttps://bsky.app/profile/jasonyanglab.org/post/3lavzhy2um22bRutgers published a very nice story on our recent work! https://www.rutgers.edu/news/researchers-reveal-why-key-tuberculosis-drug-works-against-resistant-strains14 Nov 2024 13:59 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lavzhy2um22bhttps://bsky.app/profile/jasonyanglab.org/post/3lath4m7uyc2vThrilled to share that we have 2 new manuscripts on drug-resistant #tuberculosis out at @NatureComms ! In this pair of manuscripts, we investigated changes in #mtb physiology associated with INH resistance. 1/n https://www.nature.com/articles/s41467-024-53933-8 https://www.nature.com/articles/s41467-024-54072-w13 Nov 2024 13:25 +0000at://did:plc:dcne6lrnw7x6bxvscvua3o7j/app.bsky.feed.post/3lath4m7uyc2v