Full Professor @Sorbonne_Univ_, working @LCQB_UMR7238 on protein evolution, structures, and interactions. http://www.lcqb.upmc.fr/lainehttps://bsky.app/profile/laineelodie.bsky.socialhttps://bsky.app/profile/laineelodie.bsky.social/post/3m5c6xf5v2k2cOur new special collection "Protein-Nucleic Acid Interactions: From Origins to Design (2025)" is now published in Current Opinion in Structural Biology. I'm excited to have both co-edited it with Shandar Ahmad and contributed a review! https://www.sciencedirect.com/special-issue/10P561L1WF3 https://lnkd.in/eDh62PSr10 Nov 2025 17:54 +0000at://did:plc:dik36tayly6k6buuzzck3bpm/app.bsky.feed.post/3m5c6xf5v2k2chttps://bsky.app/profile/laineelodie.bsky.social/post/3lub7w4vtsc2jVery happy to see this out! https://authors.elsevier.com/a/1lSNA3SNvcEP-G We built upon DANCE dataset to predict protein motions directly from sequences, without exploiting 3D structures! Code: https://github.com/PhyloSofS-Team/seamoon. [contains quote post or other embedded content]18 Jul 2025 19:52 +0000at://did:plc:dik36tayly6k6buuzzck3bpm/app.bsky.feed.post/3lub7w4vtsc2jhttps://bsky.app/profile/laineelodie.bsky.social/post/3lihgopq5z22fVery happy about this collective effort! We provide the community with variant effect predictions for the whole fly proteome. We validated them with annotations, population polymorphism, and CRISPR experiments. Check out your favorite protein with ProteoCast! [contains quote post or other embedded content]18 Feb 2025 14:07 +0000at://did:plc:dik36tayly6k6buuzzck3bpm/app.bsky.feed.post/3lihgopq5z22fhttps://bsky.app/profile/laineelodie.bsky.social/post/3lf5n4osjrs2jCurious about alternative splicing? Kick off the year with our latest review in COSB! https://authors.elsevier.com/sd/article/S0959440X2400206907 Jan 2025 12:20 +0000at://did:plc:dik36tayly6k6buuzzck3bpm/app.bsky.feed.post/3lf5n4osjrs2jhttps://bsky.app/profile/laineelodie.bsky.social/post/3krgxgzx4l223Very happy to introduce VespaG, for ultra-fast and accurate prediction of protein mutational effects. https://github.com/JSchlensok/VespaG. Big thanks to all authors for the great work and effort. Exciting collab with Rost lab! https://www.biorxiv.org/content/10.1101/2024.04.24.590982v101 May 2024 16:55 +0000at://did:plc:dik36tayly6k6buuzzck3bpm/app.bsky.feed.post/3krgxgzx4l223https://bsky.app/profile/laineelodie.bsky.social/post/3kl33b4ftic2wMaking protein movies from (sparse) static snapshots! Try out ou method DANCE: https://github.com/PhyloSofS-Team/DANCE. And our PDB-wide analysis of protein conformational variability: https://www.biorxiv.org/content/10.1101/2024.02.06.578951v1. Joint work with Valentin Lombard and Sergei Grudinin.10 Feb 2024 15:00 +0000at://did:plc:dik36tayly6k6buuzzck3bpm/app.bsky.feed.post/3kl33b4ftic2w