Professor of Chemistry and Nucleic Acid Chemistry @umontpellier.bsky.social Team Leader ChemBioNAC @ChemBioNAC.bsky.social www.chembionac.com #IBMMhttps://bsky.app/profile/smietana-m.bsky.socialhttps://bsky.app/profile/smietana-m.bsky.social/post/3mces4yiscc2e📢DNA templates are no longer required for efficient nucleic acid ligation. 💡We introduce Charge-Transfer Assisted Ligation (CTAL): a new templated reactivity based on π-stacking donor–acceptor interactions (DAN/NDI), not base pairing. 📄 chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.10 https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1014 Jan 2026 09:49 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3mces4yiscc2ehttps://bsky.app/profile/smietana-m.bsky.social/post/3m2rdzqslnc2wOur lastest article has just been released (Org. Biomol. Chem): Synthesis, duplex-forming properties, and enzymatic resistance of oligonucleotides containing N-acylsulfonamide linkages https://pubs.rsc.org/en/content/articlelanding/2025/ob/d5ob01382h @chembionac.bsky.social @umontpellier.bsky.social @cnrs.fr @ibmm-balard.bsky.social09 Oct 2025 14:20 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3m2rdzqslnc2whttps://bsky.app/profile/smietana-m.bsky.social/post/3lsecsmyyuc2mVery happy to share our latest publication on the Synthesis and Base-Pairing Properties of Oligonucleotides Containing 5′-(R)- and 5′-(S)-C-Aryl-thymidine now in JOC https://pubs.acs.org/doi/10.1021/acs.joc.5c00641 @chembionac.bsky.social @cnrs.fr @umontpellier.bsky.social @ibmm-balard.bsky.social24 Jun 2025 14:32 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lsecsmyyuc2mhttps://bsky.app/profile/smietana-m.bsky.social/post/3lqwdkbsomc2uOur work on Enantioselective Artificial PhotoDNAzyme now live on ChemRxiv tinyurl.com/mwtpd96u Our work merges synthetic transition-metal photocatalysis with the chiral environment of DNA to achieve visible-light-driven, enantioselective [2+2] cycloadditions.06 Jun 2025 07:42 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lqwdkbsomc2uhttps://bsky.app/profile/smietana-m.bsky.social/post/3lq7ppncqec2sThe Institute of Biomolecules Max Mousseron (ibmm.umontpellier.fr) invites applications for 2 CNRS tenure-track positions. -> Glycochemistry -> RNA Chemistry contact : du-ibmm@umontpellier.fr To apply: carrieres.cnrs.fr/recrutement-postes-de-chaires/ https://carrieres.cnrs.fr/recrutement-po…28 May 2025 07:49 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lq7ppncqec2shttps://bsky.app/profile/smietana-m.bsky.social/post/3lgsaftv76c2lVery exciting scientific day on the occasion of Jean-Jacques Vasseur' retirement. Thanks to the speakers and thanks to all the participants. Happy retirement jacques !🌴🚴🥂 @umontpellier.bsky.social @chembionac.bsky.social @ibmm-balard.bsky.social28 Jan 2025 10:24 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lgsaftv76c2lhttps://bsky.app/profile/smietana-m.bsky.social/post/3lfmgszycqs2jRecent Development of DNA‐based Biohybrid Systems Driven by Light 👉https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202401297 @chembionac.bsky.social @ibmm-balard.bsky.social @chemistryeurope.bsky.social @umontpellier.bsky.social13 Jan 2025 09:37 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lfmgszycqs2jhttps://bsky.app/profile/smietana-m.bsky.social/post/3lcicufx4gc2fZachary Pastorel has successfully defended his PhD thesis on DNA-based asymmetric catalysis. Congrats Zach ! Many thanks to the committee members @borisvauzeilles.bsky.social Olivier Baslé, Marine Desage Sami Lakhdar @umontpellier.bsky.social @chembionac.bsky.social04 Dec 2024 14:00 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lcicufx4gc2fhttps://bsky.app/profile/smietana-m.bsky.social/post/3lbuejqkyu22kOpen position : Junior Professorship in Chemical Biology / RNA chemistry Please DM for more info @cnrs.bsky.social @umontpellier.bsky.social26 Nov 2024 15:37 +0000at://did:plc:dittvos3ci4je2zmxprocaup/app.bsky.feed.post/3lbuejqkyu22k