@johnparkhill.bsky.social - John Parkhill

11 Jun 2026 15:29 +0000

Generative chemistry requires fast (~ms / molecule / GPU) and accurate retrosynthesis. Miles and Zach did a really good job with this: https://www.terraytx.ai/news-and-research/terrasynth

20 Mar 2026 18:12 +0000

-- Hiring ML Engineers time! -- Are you a smart person who wants to make therapeutics to help people using your ML chops? We will hire two engineers. We don't care about your pedigree, just your skills. Prove them by attempting the exercise linked below (<6 hours) http://164.92.115.7:5000/

28 Jan 2026 22:56 +0000

This is my new email signature.

28 Jan 2026 14:06 +0000

Getting a 6mo lead in reading papers pre arxiv : priceless. Hilarious ppl are just taking the motivations for this naively. openai.com/prism/ https://openai.com/prism/

27 Jan 2026 17:57 +0000

These are the chipotle slop bowl of science. -- Me at lunchtime.

26 Jan 2026 15:46 +0000

Carb free sweetened beef is the telelogical endpoint of American civilization, and that goal is in sight. https://arxiv.org/abs/2601.14574v1

25 Jan 2026 20:47 +0000

It's 16 years after citizens united. If you want to resist the government what you do is sell US stock, treasuries and buy gold, and foreign stock. (really)

25 Jan 2026 20:42 +0000

18 Jan 2026 19:20 +0000

If you've actually managed to avoid holiday sickness by shifting hemispheres with your family this winter or sequestering. I wanna hear from you. HOW DID YOU DO IT.

16 Jan 2026 22:03 +0000

It's basically impossible that Chat bot Ads will remain passive, because any competitor can do the agentic ads, and they will have a margin that is hundreds of times larger.

16 Jan 2026 19:01 +0000

It's sade's birthday -- The real valentine's day for those who celebrate.

01 Dec 2025 02:52 +0000

My dread of holiday flights...

06 Jun 2025 12:55 +0000

This is the way https://arxiv.org/abs/2506.04490v1

21 May 2025 15:54 +0000

Beautiful. arxiv.org/abs/2505.13447 https://arxiv.org/abs/2505.13447

07 May 2025 21:46 +0000

I can't decide how I feel about someone vibecoding what is asked for in the job description. It shows initiative? But probably should have added "oh, don't put vibecode emoji's everywhere" to the system prompt.

05 May 2025 12:55 +0000

The persistence of docking in drug design has been explained. :P https://www.nature.com/articles/s41467-025-59131-4#citeas

01 May 2025 14:02 +0000

gemini is pretty good at making manim animations with a little help, but boy without UV, manim would be impossible to install.

28 Apr 2025 17:07 +0000

If you think we can avoid Thalidomide like outcomes without animal models today, you're an idiot. If you think you're merely marketing, you should appreciate that idiots will listen to you, and the consequences will be real. I will bet anyone 1000$ if this happens it ends poorly.

25 Apr 2025 20:40 +0000

The transition between "wins nobel prize" and "says vitamin C cures mortality" or "HIV doesn't cause AIDS" or "lobotomies for everyone" or "eugenics is cool" - or "disease is over because I interpolated crystal structures" is crazy short. (all utterances of nobel prize winners)

20 Apr 2025 21:30 +0000

Only someone who can't think at 2nd order would ever take virtual cell models seriously without many unrelated breakthroughs. There are obvious, indisputable reasons they are stupid, and no one needs them more than me. [contains quote post or other embedded content]

18 Apr 2025 17:53 +0000

If your field is getting more "perspectives" papers or "position" papers, you're going to get feudalism and dreck. I'd hop :)

18 Apr 2025 17:25 +0000

"give it to god"-- god of course being the transformer.

18 Apr 2025 15:16 +0000

William Gibson owes it to the world to do another neuromancer, but where it's just descriptions of how lame the real person or prompt is behind every high follower X shitpost account. Instead of the real sexual content, dms with e-girls. Coin swindles making 5k instead of heists

15 Apr 2025 18:00 +0000

15 Apr 2025 17:47 +0000

14 Apr 2025 18:36 +0000

If universities don't stand up to the "dark enlightenment" they will lose all their relevance. [contains quote post or other embedded content]

10 Apr 2025 15:05 +0000

We're Hiring. https://ats.rippling.com/terraytx/jobs/c37e2def-a877-4058-aac1-ee42cee32ffe?jobSite=LinkedIn

03 Apr 2025 04:59 +0000

The amount of disrespect one has for other people's thoughts, is often crazily proportional to how desperately one craves approval and validation. It's a joke embedded in humanity.

01 Apr 2025 01:03 +0000

Imagine getting ratio'd by a guy with half your rizz on your own crappy propaganda platform 😂