Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research. https://www.nature.com/nrc/https://bsky.app/profile/natrevcancer.nature.comhttps://bsky.app/profile/natrevcancer.nature.com/post/3ml6zsswqgo2e#COMMENT Here, Lupo and Plon highlight links between congenital anomalies and cancer, calling for population‑based and molecular studies to identify risk markers and inform surveillance and precision therapies. 📖 👇 http://dlvr.it/TSPZSx06 May 2026 15:37 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3ml6zsswqgo2ehttps://bsky.app/profile/natrevcancer.nature.com/post/3ml4j6izsy22a#REVIEW 🚨 This Review examines how microenvironmental cues, epigenetic programmes & immune interactions govern disseminated cancer cell dormancy + how this may guide the development of biomarkers & therapies to prevent metastatic relapse. 📖 👇 http://dlvr.it/TSNYvx05 May 2026 15:34 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3ml4j6izsy22ahttps://bsky.app/profile/natrevcancer.nature.com/post/3mkpw7iaizf2dOur MAY issue is now live! 💐 🌞 💐 It features #REVIEWs on: - Metabolomics for studying cancer across scales - Intestinal microbiota in acute GvHD - AI-generated synthetic data for cancer research + trials - Claudins as therapeutic targets 📖 👇 http://dlvr.it/TSJRtv30 Apr 2026 15:23 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkpw7iaizf2dhttps://bsky.app/profile/natrevcancer.nature.com/post/3mkngdb7jyw2p#REVIEW 🚨 In this Review, Zhao & Shilatifard examine how mutations in components of the KMT2C-containing or KMT2D-containing COMPASS complex drive cancer progression and discuss therapeutic approaches targeting vulnerabilities arising from this. 📖 👇 http://dlvr.it/TSHTrX29 Apr 2026 15:33 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkngdb7jyw2phttps://bsky.app/profile/natrevcancer.nature.com/post/3mkl4sngrzc2wMake sure to register for this exciting meeting in London on the 17-19th June exploring cancer and its interactions with the host....final few places available. Our Chief Editor Anna Dart will be there👇 [contains quote post or other embedded content]28 Apr 2026 17:37 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkl4sngrzc2whttps://bsky.app/profile/natrevcancer.nature.com/post/3mkkvqq22tp2n#REVIEW 🚨 Chang et al. describe context‑dependent synthetic lethality, showing how genetic contexts create tumor vulnerabilities and inform selective, durable cancer therapies. 📖 👇 http://dlvr.it/TSGWQM28 Apr 2026 15:31 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkkvqq22tp2nhttps://bsky.app/profile/natrevcancer.nature.com/post/3mkif77qhy22w#REVIEW 🚨 In this Review, Liu and colleagues highlight how AI could be harnessed for integrating multi-omics data to provide patient-specific insights into cancer mechanisms and treatment response. 👇 📖 http://dlvr.it/TSFZLr27 Apr 2026 15:30 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkif77qhy22whttps://bsky.app/profile/natrevcancer.nature.com/post/3mkd7qozxzj2w#ToolsoftheTrade 🚨 Zhengyuan Pang describes the development and use of volumetric clearing-assisted tissue click chemistry (vCATCH), a pipeline that enables mapping of covalent drug binding at cellular resolution across a mouse body. 📖👇 http://dlvr.it/TSD6Mm25 Apr 2026 14:09 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkd7qozxzj2whttps://bsky.app/profile/natrevcancer.nature.com/post/3mkb6zzhlgr2e http://dlvr.it/TSCZTK24 Apr 2026 18:51 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkb6zzhlgr2ehttps://bsky.app/profile/natrevcancer.nature.com/post/3mkb6zxeiks2d http://dlvr.it/TSCZSs24 Apr 2026 18:51 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkb6zxeiks2dhttps://bsky.app/profile/natrevcancer.nature.com/post/3mkau2k3tbt2w#Progress🚨 Schneider et al. highlight the role of the microbiome in driving Immune-related adverse events #irAEs development and progression, particularly immune checkpoint inhibitor-associated colitis and discussing strategies to mitigate risks. 📖👇 http://dlvr.it/TSCQFH24 Apr 2026 15:34 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mkau2k3tbt2whttps://bsky.app/profile/natrevcancer.nature.com/post/3mk6x6jehzg2n http://dlvr.it/TSBjPp23 Apr 2026 21:25 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mk6x6jehzg2nhttps://bsky.app/profile/natrevcancer.nature.com/post/3mk6cts5pes2z#Review🚨 Metabolic dysfunction associated steatotic liver disease #MASLD and alcoholic liver disease #ALD drive liver cancer. Heikenwälder&Co review mechanisms of disease progression and therapeutic advances to reduce cancer risk. 📖👇 http://dlvr.it/TSBQNJ23 Apr 2026 15:21 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mk6cts5pes2zhttps://bsky.app/profile/natrevcancer.nature.com/post/3mk3ns57dzn22#ExpertRecommendation🚨 A group of experts review a decade of progress in research and treatment of high-grade serous carcinoma, highlighting remaining challenges and setting priorities to reduce incidence & improve outcomes. @Qmbci.bsky.social @qmul.bsky.social 📖👇 http://dlvr.it/TS9LHx22 Apr 2026 13:59 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mk3ns57dzn22https://bsky.app/profile/natrevcancer.nature.com/post/3mk3nhulefi2e http://dlvr.it/TS9L4V22 Apr 2026 13:53 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mk3nhulefi2ehttps://bsky.app/profile/natrevcancer.nature.com/post/3mjysdgs7dp2z http://dlvr.it/TS88qT21 Apr 2026 10:42 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjysdgs7dp2zhttps://bsky.app/profile/natrevcancer.nature.com/post/3mjmpxntzlr2l http://dlvr.it/TS4CWt16 Apr 2026 15:28 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjmpxntzlr2lhttps://bsky.app/profile/natrevcancer.nature.com/post/3mjmolnxcwv2m#RESEARCH HIGHLIGHT Gudenas et al. map pineoblastoma subgroups to pinealocyte progenitors and identify a shared photoreceptor-like transcriptional network, revealing a developmental vulnerability with therapeutic potential. http://dlvr.it/TS4BBq16 Apr 2026 15:03 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjmolnxcwv2mhttps://bsky.app/profile/natrevcancer.nature.com/post/3mjjxgx3mt62h http://dlvr.it/TS35fr15 Apr 2026 13:04 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjjxgx3mt62hhttps://bsky.app/profile/natrevcancer.nature.com/post/3mjhx35ozwa2q http://dlvr.it/TS2NB214 Apr 2026 17:52 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjhx35ozwa2qhttps://bsky.app/profile/natrevcancer.nature.com/post/3mjhnpklxua2d#RESEARCHIGHLIGHT 🚨 Wang et al. investigated the functional role of tumour-associated visceral adipose tissue in regulating colorectal cancer anti-tumour immunity and immunotherapy efficacy. http://dlvr.it/TS2Cny14 Apr 2026 15:04 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjhnpklxua2dhttps://bsky.app/profile/natrevcancer.nature.com/post/3mjeyzw6o452j http://dlvr.it/TS199X13 Apr 2026 13:49 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mjeyzw6o452jhttps://bsky.app/profile/natrevcancer.nature.com/post/3mj6qunayrr2x http://dlvr.it/TRzRVl11 Apr 2026 02:07 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mj6qunayrr2xhttps://bsky.app/profile/natrevcancer.nature.com/post/3mijlo3phgt2x#COMMENT 🚨 Wang & Chaudhari advocate for the use of artificial intelligence (AI)-driven smart patient-retrieval systems to facilitate more informed & individualized clinical decision-making. 📖 👇 http://dlvr.it/TRrBCj02 Apr 2026 16:08 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mijlo3phgt2xhttps://bsky.app/profile/natrevcancer.nature.com/post/3mih2o6fjhs26🚨 #REVIEW 🚨 Type I IFNs influence cancer progression, development & therapeutic response. @belindaparker.bsky.social, Haynes & colleagues explore the complexity of IFN signalling, & outline strategies for reprogramming IFN activity in tumours. 👇 📖 http://dlvr.it/TRq8gr01 Apr 2026 15:58 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mih2o6fjhs26https://bsky.app/profile/natrevcancer.nature.com/post/3mifkrq26xs26 http://dlvr.it/TRpVls01 Apr 2026 01:41 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mifkrq26xs26https://bsky.app/profile/natrevcancer.nature.com/post/3miehca7anr2x#ToolsoftheTrade 🚨 Here, Yifan Zhang describes the development & use of FOCAS, a platform for site-specific, transcriptome-wide mapping of functional m6A RNA modifications, uncovering epitranscriptomic and epigenomic interactions that shape cancer cell fitness. 👇 📖 http://dlvr.it/TRp3Jr31 Mar 2026 15:06 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3miehca7anr2xhttps://bsky.app/profile/natrevcancer.nature.com/post/3miczlhkudu25 http://dlvr.it/TRnRl731 Mar 2026 01:28 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3miczlhkudu25https://bsky.app/profile/natrevcancer.nature.com/post/3mibzdq3lcp26Our APRIL issue is live! 🌦️ 💐 It features articles on: - the role of l-Fucose in cancer biology & therapy - AI in cancer research & oncology - Radiation as an immune modulator - Cellular crosstalk & architecture of PDAC 👇 📖 http://dlvr.it/TRn49D30 Mar 2026 15:51 +0000at://did:plc:dn6fixr3gc5fqz6uqotfmesh/app.bsky.feed.post/3mibzdq3lcp26