Associate editor Science Magazine Immunology | Haematology | Host-pathogen interactions https://bsky.app/profile/sarahhross.bsky.socialhttps://bsky.app/profile/sarahhross.bsky.social/post/3melo7fqqys2hThe closing date is approaching - don't miss out! ⤵️ [contains quote post or other embedded content]11 Feb 2026 14:18 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3melo7fqqys2hhttps://bsky.app/profile/sarahhross.bsky.social/post/3mca5jyube325If you're doing innovative research about #microbiota and received an MD &/or PhD in last 10 yrs don’t forget to apply for the NOSTER & @science.org Microbiome Prize! Grand Prize: $25K & your essay published in Science Magazine Deadline: Feb 14th Enter: buff.ly/5GKZgUN12 Jan 2026 13:30 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3mca5jyube325https://bsky.app/profile/sarahhross.bsky.social/post/3lwode3yswo2xWell, this is rather wonderful! #IUIS202518 Aug 2025 11:49 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwode3yswo2xhttps://bsky.app/profile/sarahhross.bsky.social/post/3lwjzlywqbg2fThe human immune system evolved over millennia - and can adapt within a single lifetime. This review examines how the immune responses change over the life course. By Jessica Metcalf, Andrea Graham, Andrew Yates and Derek Cummings @science.org buff.ly/GJpPUO716 Aug 2025 18:44 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwjzlywqbg2fhttps://bsky.app/profile/sarahhross.bsky.social/post/3lwjtmtkh7m22Tissue immunity meets biological sex differences - context is important in the immune system. Another of my reading recommendations during a trip to @iuis-online.bsky.social Congress. From Sonia Sharma, Alicia Gibbons and Erica Ollmann Saphire in @science.org buff.ly/XPN0Tpb16 Aug 2025 16:57 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwjtmtkh7m22https://bsky.app/profile/sarahhross.bsky.social/post/3lwjot26gub2iIf you are looking for a great read during your journey to @iuis-online.bsky.social Congress, take a peek at this review from from Matthias Nahrendorf, Florent Ginhoux and @filswirski.bsky.social in @science.org that explores the role of immune cells beyond host defence. buff.ly/S5RkqTf16 Aug 2025 15:31 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwjot26gub2ihttps://bsky.app/profile/sarahhross.bsky.social/post/3lwjgotgwhm2kAnyone traveling to @iuis-online.bsky.social Congress and looking for something to read? Don't miss the reviews from our @science.org Evolving Immunity Special Issue! Here, Kassiotis and Stoye consider endogenous retroviruses and antiviral defences. buff.ly/IU4nbSE16 Aug 2025 13:05 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwjgotgwhm2khttps://bsky.app/profile/sarahhross.bsky.social/post/3lwjfcrn2nk2eSuch a beautiful and intricate image! I was fascinated by the creative process for the cover, and loved getting a behind-the-scenes look at the work of artist Rioka Hayama and the Science Visuals team. Have you guessed all the features yet? [contains quote post or other embedded content]16 Aug 2025 12:40 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwjfcrn2nk2ehttps://bsky.app/profile/sarahhross.bsky.social/post/3lwjd23fo422iNot long to go - I'm looking forward to some fantastic immunology! [contains quote post or other embedded content]16 Aug 2025 12:00 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lwjd23fo422ihttps://bsky.app/profile/sarahhross.bsky.social/post/3lvtdt2e27s2mThis week @science.org examines the wonders of the immune system! From molecular defences that co-evolved with pathogens to specialised cells that are intricately linked with physiology, the immune system is attuned to biological sex and different stages of life. [contains quote post or other embedded content]07 Aug 2025 18:15 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lvtdt2e27s2mhttps://bsky.app/profile/sarahhross.bsky.social/post/3lmkg6cqh5k2v#Immunology out now @science.org After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/49bKcTG By Jobin, Seetharama, Rüttger et al.11 Apr 2025 16:17 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lmkg6cqh5k2vhttps://bsky.app/profile/sarahhross.bsky.social/post/3llyq2kx25d2f#Immunology out now @science.org Regulatory T cells inhibit pain sensing in female, but not male, mice. buff.ly/SKtHnfK By Élora Midavaine, Sakeen Kashem et al.04 Apr 2025 15:26 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3llyq2kx25d2fhttps://bsky.app/profile/sarahhross.bsky.social/post/3lkdw7irwdj2hICYMI by First release - now in print @science.org Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection. buff.ly/3DjNQ1e By @cicacanesso.bsky.social @danmucida.bsky.social @victora.bsky.social et al14 Mar 2025 15:25 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lkdw7irwdj2hhttps://bsky.app/profile/sarahhross.bsky.social/post/3lj6mdz4pgn2q#Immunology by First Release @science.org In mice, during immune responses accompanied by elevated self-antigens, autoreactive CD4 T cells must be restrained by regulatory CD4 T cells with the same antigen specificity to prevent autoimmunity. buff.ly/3EXaXQa27 Feb 2025 19:20 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lj6mdz4pgn2qhttps://bsky.app/profile/sarahhross.bsky.social/post/3limzwb32432z#Immunology out now @science.org Machine learning, using the sequences of an individual's B and T cell receptors, has the potential to diagnose immune-related diseases. https://buff.ly/3QvxSVf By Maxim Zaslavsky, Erin Craig, @anshulkundaje.bsky.social , @scottboydlab.bsky.social et al.20 Feb 2025 19:35 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3limzwb32432zhttps://bsky.app/profile/sarahhross.bsky.social/post/3li3gwulkxf2i#Immunology out now @science.org In mice, the transcription factor KLF2 keeps activated CD8 T cells on track to differentiate into functional effector T cells. https://buff.ly/4hBmL8W By Eric Fagerberg, Nikhil Joshi @nikjoshilabyale.bsky.social et al13 Feb 2025 19:40 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3li3gwulkxf2ihttps://bsky.app/profile/sarahhross.bsky.social/post/3lhm4lt2pmn2wICYMI by First Release - now officially in print @science.org Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations. https://buff.ly/4gvqKTz From Shixin Ma, Sue Kaech @tcellogic.bsky.social et al. #immunometabolism07 Feb 2025 17:25 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lhm4lt2pmn2whttps://bsky.app/profile/sarahhross.bsky.social/post/3lhgsmlz4kk26Not long to go now! Don’t miss out on applying for the NOSTER & @science.org Microbiome Prize! Enter: buff.ly/4gS29ZH More details: ⤵️ [contains quote post or other embedded content]05 Feb 2025 14:43 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lhgsmlz4kk26https://bsky.app/profile/sarahhross.bsky.social/post/3lh236xko2c2fThis Perspective from Aaron Ver Heul puts the work of Andrew Liu, @danhkaplan.bsky.social et al into context. https://buff.ly/40Bp1G1 #Immunology @science.org31 Jan 2025 13:12 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lh236xko2c2fhttps://bsky.app/profile/sarahhross.bsky.social/post/3lh22sgtker2k#Immunology out now @science.org Scratching in mice promotes pain-sensing neurons to release a neuropeptide that stimulated antigen-activated mast cells to degranulate and produce inflammatory mediators. https://buff.ly/4hDAgF2 From Andrew Liu, @danhkaplan.bsky.social et al31 Jan 2025 13:05 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lh22sgtker2khttps://bsky.app/profile/sarahhross.bsky.social/post/3lgipaqvk4r2jICYMI by First Release - now officially in print @science.org Plasma cells producing high-affinity antibodies dominate the plasma cell population through increased proliferation. https://buff.ly/3BzpLmL By Andrew MacLean, Michel Nussenzweig et al. #Immunology24 Jan 2025 15:23 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lgipaqvk4r2jhttps://bsky.app/profile/sarahhross.bsky.social/post/3lfuyrhfwih22#Immunology out now @science.org ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting. https://buff.ly/42iBst016 Jan 2025 19:20 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lfuyrhfwih22https://bsky.app/profile/sarahhross.bsky.social/post/3lfprhiru642kIf you're doing innovative research about #microbiota and received an MD &/or PhD in last 10 years don’t miss out on applying for the NOSTER & @science.org Microbiome Prize! Grand Prize: $25K & your essay published in Science Magazine Deadline: Feb 14th Enter: https://buff.ly/4gS29ZH14 Jan 2025 17:26 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3lfprhiru642khttps://bsky.app/profile/sarahhross.bsky.social/post/3ldooo6pnzh2f#Immunology by first release now @science.org Plasma cells producing high-affinity antibodies dominate the plasma cell population through increased proliferation. https://buff.ly/3BzpLmL By Andrew MacLean, Michel Nussenzweig et al.19 Dec 2024 20:13 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldooo6pnzh2fhttps://bsky.app/profile/sarahhross.bsky.social/post/3ldoofatmbe2z#Immunology by First release now @science.org Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection https://buff.ly/3DjNQ1e By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.19 Dec 2024 20:08 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldoofatmbe2zhttps://bsky.app/profile/sarahhross.bsky.social/post/3ldoo7vfroe2i#Immunology out now @science.org An unstructured region within MAVS interacts with cellular, rather than viral, RNA. This alters how MAVS interacts with other proteins and influences antiviral responses. https://buff.ly/4grnf18 By @nandangokhale.bsky.social with @ramlabuw.bsky.social et al.19 Dec 2024 20:05 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldoo7vfroe2ihttps://bsky.app/profile/sarahhross.bsky.social/post/3ldoo2jhicg2z#Immunology out now @science.org Biased antibody responses to influenza strains in vaccines are strongly linked to genetics. Coupling antigens from different strains together may broaden antibody responses. https://buff.ly/4flV5TK By Vamsee Mallajosyula, Mark Davis et al.19 Dec 2024 20:02 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldoo2jhicg2zhttps://bsky.app/profile/sarahhross.bsky.social/post/3ldonv454d223I am excited to say, we have not one but FOUR #Immunology Research Articles out this week @science.org! Individual posts to follow!19 Dec 2024 19:59 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldonv454d223https://bsky.app/profile/sarahhross.bsky.social/post/3ldly65fkfa23From Feb '24: A treatment combining a soluble IL-15 superagonist with broadly neutralizing antibodies against the HIV-1 envelope protein induced long-term viral control in rhesus macaques infected with SIV-HIV. https://buff.ly/3ZZdYY4 #Immunology #HIV @science.org18 Dec 2024 18:25 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldly65fkfa23https://bsky.app/profile/sarahhross.bsky.social/post/3ldlu77gey22eFrom Sept '24: Computational approaches identified a localized flexible region within the F protein of RSV that could be mutated to keep the protein in the prefusion state when used as a vaccine antigen. https://buff.ly/4gAS8zy #Immunology #Vaccines @science.org18 Dec 2024 17:14 +0000at://did:plc:eda44xddrs3q6zckadjtflca/app.bsky.feed.post/3ldlu77gey22e