Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. Part of @natureportfolio.bsky.social Repost/like=interesting/relevant, not necessarily endorsement.https://bsky.app/profile/natgenet.nature.comhttps://bsky.app/profile/natgenet.nature.com/post/3mrpo6rncmc2s📢PUBLISHED @natgenet.nature.com 📰Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects. By Siyang Liu, Fengxiang Wei and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02677-w?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Jul 2026 14:56 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpo6rncmc2shttps://bsky.app/profile/natgenet.nature.com/post/3mrpo42fkoc2s📢PUBLISHED @natgenet.nature.com 📰Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants. By Liudan Jiang, Chuan He and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02685-w?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Jul 2026 14:54 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpo42fkoc2shttps://bsky.app/profile/natgenet.nature.com/post/3mrpnzb74us2s📢PUBLISHED @natgenet.nature.com 📰Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber. By Jiantao Guan, Shengping Zhang and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02682-z?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Jul 2026 14:52 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpnzb74us2shttps://bsky.app/profile/natgenet.nature.com/post/3mrpnsxrm222s📢PUBLISHED @natgenet.nature.com 📰SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry. By Brian J. Liddicoat, Jesse J. Balic, @mafdawson.bsky.social and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02664-1?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Jul 2026 14:49 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpnsxrm222shttps://bsky.app/profile/natgenet.nature.com/post/3mrpnomtzas2s📢PUBLISHED @natgenet.nature.com 📰Promoter strength and position govern promoter competition through transcript-dependent insulation. By Mervenaz Koska, Joanna Wysocka and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02691-y?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Jul 2026 14:46 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpnomtzas2shttps://bsky.app/profile/natgenet.nature.com/post/3mrpnl2mzc22s📢PUBLISHED @natgenet.nature.com 📰Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders. By Fabian Streit, Stephanie H. Witt and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02654-3?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Jul 2026 14:44 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpnl2mzc22shttps://bsky.app/profile/natgenet.nature.com/post/3mrpnhyekak2s📢PUBLISHED @natgenet.nature.com 📰Pioneer transcription factors direct tissue-specific cohesin chromatin entry and three-dimensional genome organization. By Song Wang, Haiyang Guo and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02688-728 Jul 2026 14:43 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mrpnhyekak2shttps://bsky.app/profile/natgenet.nature.com/post/3mqqtykjims2t💫PUBLISHED @natgenet.nature.com 📰Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation. By @masashi-nomura.bsky.social, @landau.bsky.social, Mario L. Suvà and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02642-7?utm_source=bluesky&utm_medium=social&utm_campaign=ng16 Jul 2026 08:47 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mqqtykjims2thttps://bsky.app/profile/natgenet.nature.com/post/3mqqtr2gvu22t📢PUBLISHED @natgenet.nature.com 📰A progeria syndrome links DNA hypermethylation to age-related pathology. By Dan Sarni, Andrew Jackson and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02633-8?utm_source=bluesky&utm_medium=social&utm_campaign=ng16 Jul 2026 08:43 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mqqtr2gvu22thttps://bsky.app/profile/natgenet.nature.com/post/3mqqtn7nmkc2t✨PUBLISHED @natgenet.nature.com 📰Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease. By Ryan C. Chai, John P. Kemp and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02640-9?utm_source=bluesky&utm_medium=social&utm_campaign=ng16 Jul 2026 08:41 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mqqtn7nmkc2thttps://bsky.app/profile/natgenet.nature.com/post/3mqqt456ve22z📢@natgenet.nature.com July issue's out! Featuring: ✅special focus on BRCA1 and BRAC2 ✅in vivo Perturb-seq of MDD risk genes ✅human vaginal microbiome genomic landscape ✅Chron's Disease single-cell RNA seq atlas ✅a graph-based mung bean pan-genome and much more! ⬇️ https://www.nature.com/ng/volumes/58/issues/7?utm_source=bluesky&utm_medium=social&utm_campaign=ng16 Jul 2026 08:31 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mqqt456ve22zhttps://bsky.app/profile/natgenet.nature.com/post/3mq6jmbqv6k2d@natgenet.nature.com is looking to hire a Cancer editor! Please repost and share with your contacts! This is a rare and exciting opportunity. https://springernature.wd3.myworkdayjobs.com/SpringerNatureCareers/job/Shanghai/Associate-or-Senior-Editor--Nature-Genetics_JR10649409 Jul 2026 01:53 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mq6jmbqv6k2dhttps://bsky.app/profile/natgenet.nature.com/post/3mkk5u5cbf22c📢PUBLISHED @natgenet.nature.com 📰 Interpretable, flexible and spatially aware integration of multiple spatial transcriptomics datasets from diverse sources By Jia Zhao, Hongyu Zhao and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02579-x?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Apr 2026 08:24 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mkk5u5cbf22chttps://bsky.app/profile/natgenet.nature.com/post/3mkk455b4zc2c📢 PUBLISHED @natgenet.nature.com 📰Tumor DNA methylation subtypes predict immunotherapy outcomes in pleural mesothelioma patients in the NIBIT-EPI-MESO study By Luana Calabrò, Michele Ceccarelli, Michele Maio and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02580-4?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Apr 2026 07:53 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mkk455b4zc2chttps://bsky.app/profile/natgenet.nature.com/post/3mkk3xk7nbc2c📢 PUBLISHED @natgenet.nature.com 📰Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome By Loes M. E. Moolhuijsen, Corrine K. Welt, Tugce Karaderi, Felix R. Day and colleagues. ⬇️ https://www.nature.com/articles/s41588-026-02543-9?utm_source=bluesky&utm_medium=social&utm_campaign=ng28 Apr 2026 07:50 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3mkk3xk7nbc2chttps://bsky.app/profile/natgenet.nature.com/post/3m22iowx2ts24📢OUT TODAY @natgenet.nature.com 📰Limited overlap between genetic effects on disease susceptibility and disease survival. By Zhiyu Yang, Nina Mars, Andrea Ganna and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02342-8?utm_source=bluesky&utm_medium=social&utm_campaign=ng30 Sep 2025 12:12 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3m22iowx2ts24https://bsky.app/profile/natgenet.nature.com/post/3lzzz3mzff22i📢OUT @natgenet.nature.com 📰Bryophytes hold a larger gene family space than vascular plants. By Shanshan Dong, Yang Liu and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02325-9?utm_source=bluesky&utm_medium=social&utm_campaign=ng30 Sep 2025 07:33 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lzzz3mzff22ihttps://bsky.app/profile/natgenet.nature.com/post/3lzy5uu4asc2l📢PUBLISHED @natgenet.nature.com 📰Rapid epigenomic classification of acute leukemia By Til L. Steinicke, Gabriel K. Griffin, Volker Hovestadt and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02321-z?utm_source=bluesky&utm_medium=social&utm_campaign=ng29 Sep 2025 13:53 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lzy5uu4asc2lhttps://bsky.app/profile/natgenet.nature.com/post/3lzy5rtde7k2l📢PUBLISHED @natgenet.nature.com 📰Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects. By Konrad J. Karczewski, Alicia R. Martin and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02335-7?utm_source=bluesky&utm_medium=social&utm_campaign=ng29 Sep 2025 13:51 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lzy5rtde7k2lhttps://bsky.app/profile/natgenet.nature.com/post/3lzy5pdwz722l📢PUBLISHED @natgenet.nature.com 📰Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks. By Ching-Huang Ho, John P. Ray and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02301-3?utm_source=bluesky&utm_medium=social&utm_campaign=ng29 Sep 2025 13:50 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lzy5pdwz722lhttps://bsky.app/profile/natgenet.nature.com/post/3lzy5lzuysc2l📢PUBLISHED @natgenet.nature.com 📰 Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. By Camiel M. van der Laan, Dorret I. Boomsma and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02295-y?utm_source=bluesky&utm_medium=social&utm_campaign=ng29 Sep 2025 13:48 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lzy5lzuysc2lhttps://bsky.app/profile/natgenet.nature.com/post/3lyuqsvg25s2x📢📢REVIEW PUBLISHED TODAY @natgenet.nature.com 📰Advancing biological understanding of cellular senescence with computational multiomics. By Sheng Li, SenNet Consortium, and colleagues! ⬇️ https://www.nature.com/articles/s41588-025-02314-y?utm_source=bluesky&utm_medium=social&utm_campaign=ng15 Sep 2025 11:56 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lyuqsvg25s2xhttps://bsky.app/profile/natgenet.nature.com/post/3lyuqmpfbs22x📢OUT @natgenet.nature.com 📰DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution. By Francisco Gimeno-Valiente, Nnennaya Kanu and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02307-x?utm_source=bluesky&utm_medium=social&utm_campaign=ng15 Sep 2025 11:53 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lyuqmpfbs22xhttps://bsky.app/profile/natgenet.nature.com/post/3lyuqjip4ks2x📢OUT @natgenet.nature.com 📰Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions. By Aliza P. Wingo, Thomas S. Wingo and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02291-2?utm_source=bluesky&utm_medium=social&utm_campaign=ng15 Sep 2025 11:51 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lyuqjip4ks2xhttps://bsky.app/profile/natgenet.nature.com/post/3lyuqaovf6k2x📢The September issue of @natgenet.nature.com is out! Featuring: ✅multiomic analysis in NSCLC ✅ancestral recombination graphs with SINGER ✅mutational landscape of TNBC in African American women ✅scDNAme&3Dgenome atlas of human SAT ✅avena super-pangenome &more! ⬇️ https://www.nature.com/ng/volumes/57/issues/9?utm_source=bluesky&utm_medium=social&utm_campaign=ng15 Sep 2025 11:46 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3lyuqaovf6k2xhttps://bsky.app/profile/natgenet.nature.com/post/3ly3oj6yixk2k📢 OUT TODAY @natgenet.nature.com 🐄A multi-tissue single-cell expression atlas in cattle🐄 By Bo Han, Dongxiao Sun, Lingzhao Fang and colleagues. ⬇️ https://www.nature.com/articles/s41588-025-02329-5?utm_source=bluesky&utm_medium=social&utm_campaign=ng05 Sep 2025 12:38 +0000at://did:plc:eeo434sskhhao35cqzfbuljk/app.bsky.feed.post/3ly3oj6yixk2k