SFB1361 "Regulation of DNA Repair and Genome Stability" Imprint: https://sfb1361.de/imprinthttps://bsky.app/profile/sfb1361.bsky.socialhttps://bsky.app/profile/sfb1361.bsky.social/post/3mk5xwvqf7k2qHuge thanks to everyone who joined our IMB & SFB 1361 conference in Mainz!🎊 “The Evil Within: Regulation and Repair of Endogenous DNA Damage” explored how cells detect, respond to & repair internal genetic threats.🧬 It was great seeing you all! @imbmainz.bsky.social #ISC26DNArepair23 Apr 2026 12:06 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mk5xwvqf7k2qhttps://bsky.app/profile/sfb1361.bsky.social/post/3mk5v46f5xk2qNew publication!!📑 Congrats to the Hofmann lab on their new article exploring how Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model. 🔎Read more here: https://www.nature.com/articles/s41467-026-69914-y23 Apr 2026 11:15 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mk5v46f5xk2qhttps://bsky.app/profile/sfb1361.bsky.social/post/3mie4uqca2k2zPublication alert!! 📃 Congratulations to the Hopfner lab (@hopfnerlab.bsky.social) on their new publication: "Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complex" 🔎Find out more here: https://doi.org/10.1093/nar/gkag138 [contains quote post or other embedded content]31 Mar 2026 12:00 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mie4uqca2k2zhttps://bsky.app/profile/sfb1361.bsky.social/post/3mie4dghpws2zNew publication!📃 Happy to share the new joint publication by our #SFB1361 PI's Julian Stingele (@jstingele.bsky.social) and Petra Beli, covering how RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response. Read more here: https://www.sciencedirect.com/science/article/pii/S1097276526001383?via%3Dihub31 Mar 2026 11:50 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mie4dghpws2zhttps://bsky.app/profile/sfb1361.bsky.social/post/3mey3umoqd22pNew publication!!📑 Congrats to the Carell lab on their new paper: "One-Step and universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U" 🔎Read more here: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.20250284816 Feb 2026 12:54 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mey3umoqd22phttps://bsky.app/profile/sfb1361.bsky.social/post/3mey3kl7tns2pPublication alert!!📑 Congrats to the @dikiclab.bsky.social and Beli labs on their joint #SFB1361 publication, covering how DNA-protein cross-links promote cGAS-STING-driven premature aging and embryonic lethality. 🔎Read the paper here: https://www.science.org/doi/10.1126/science.adx944516 Feb 2026 12:49 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mey3kl7tns2phttps://bsky.app/profile/sfb1361.bsky.social/post/3mduos2hnlk24SFB 1361 member - Dr Andriana Kotini - will present a poster at "The Evil Within: Regulation and Repair of Endogenous DNA Damage" (IMB Mainz, 10-13 March 2026)👩‍🏫 Join us to connect, discuss and collaborate! Details & registration: www.sfb1361.de/dnarepairconf2026 #SFB1361 #IMBMainz #ISC26DNArepair02 Feb 2026 10:57 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mduos2hnlk24https://bsky.app/profile/sfb1361.bsky.social/post/3mdnaggvbj22gSFB 1361 member - Dr Natalie Schindler (@scientistwithheart.bsky.social) - shares a preview of her short talk at our upcoming conference 👩‍🏫 Dive into details at @imbmainz.bsky.social in Mainz this 10-13 March 2026! Register now: www.sfb1361.de/dnarepairconf2026 #SFB1361 #IMBMainz #ISC26DNArepair30 Jan 2026 11:51 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mdnaggvbj22ghttps://bsky.app/profile/sfb1361.bsky.social/post/3mdn2yuy3hc2cPreprint alert!!📑 We're happy to share a new preprint from our associated member, Dr Maximilian Reuter (@reuterlm.bsky.social), on "Mechanisms of MCM2-7 helicase activation and initial DNA melting at near base-pair resolution"  🔎Read more here: https://www.biorxiv.org/content/10.64898/2026.01.27.699880v1 [contains quote post or other embedded content]30 Jan 2026 10:14 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mdn2yuy3hc2chttps://bsky.app/profile/sfb1361.bsky.social/post/3mddcsu4lb22vSFB 1361 member - Dr Carolin Wagner - will present a short talk at our upcoming conference 👩‍🏫 Don't miss out and come join her at @imbmainz.bsky.social! Registration closes 02 Feb → www.sfb1361.de/dnarepairconf2026 #SFB1361 #IMBMainz #ISC26DNArepair26 Jan 2026 13:07 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3mddcsu4lb22vhttps://bsky.app/profile/sfb1361.bsky.social/post/3madgjkkztk2mOur speaker - Prof. Helle Ulrich - invites fresh perspectives on DNA repair & genome stability. 🧬 Continue the conversation at our conference "The Evil Within: Regulation and Repair of Endogenous DNA Damage." (IMB Mainz, 10–13 Mar 2026). Register → www.sfb1361.de/dnarepairconf202619 Dec 2025 09:58 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3madgjkkztk2mhttps://bsky.app/profile/sfb1361.bsky.social/post/3m7nb5vaiyc2aLoving @drewberry.bsky.social's beautiful animation of DNA break repair by HR - featuring the MRN complex architecture and function inspired by the research from @hopfnerlab.bsky.social! Dive into the science behind it🧬 https://www.sciencedirect.com/science/article/pii/S1097276522011388 https://www.nature.com/articles/s41467-025-64082-x [contains quote post or other embedded content]10 Dec 2025 14:24 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m7nb5vaiyc2ahttps://bsky.app/profile/sfb1361.bsky.social/post/3m7ajjnpzok2oPublication alert!! 📃 Congratulations to the @hopfnerlab.bsky.social on the great work! 🔎Read the paper here: https://www.sciencedirect.com/science/article/pii/S1097276525008275?via%3Dihub [contains quote post or other embedded content]05 Dec 2025 12:49 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m7ajjnpzok2ohttps://bsky.app/profile/sfb1361.bsky.social/post/3m6z7hxhl3s24📢Abstract deadline extended to Mon, 15 Dec, 23:59 CET! Good news! You now have a few more days to submit your abstract to present a short talk or poster at the IMB & SFB 1361 conference. 📑Find more info here: https://sfb1361.de/dnarepairconf2026/registration-abstracts/abstracts #ISC26DNArepair #SFB1361 #IMBMainz02 Dec 2025 15:00 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m6z7hxhl3s24https://bsky.app/profile/sfb1361.bsky.social/post/3m6jmaqhfhk2zDon't forget - Early Bird Registration and Abstract Submission closes on 1 December. Register now via www.sfb1361.de/dnarepairconf2026 We can’t wait to see you in March! #ISC26DNArepair #SFB1361 [contains quote post or other embedded content]26 Nov 2025 10:06 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m6jmaqhfhk2zhttps://bsky.app/profile/sfb1361.bsky.social/post/3m6jknymf2k2z📃Just published: new joint #SFB1361 publication by the Luke and Ulrich labs! The article focuses on how Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict. 🔎Find out more here: https://www.sciencedirect.com/science/article/pii/S2211124725013373?via%3Dihub26 Nov 2025 09:38 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m6jknymf2k2zhttps://bsky.app/profile/sfb1361.bsky.social/post/3m5jivbcgvs2nWe are excited to share that our #SFB1361 alumni, Dr Gabriel M. C. Longo, received a Walter Benjamin Fellowship to support his postdoctoral research in the Kleinstiver lab at Harvard Medical School/Massachusetts General Hospital, Boston. Congratulations! 🎉🎉13 Nov 2025 15:41 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m5jivbcgvs2nhttps://bsky.app/profile/sfb1361.bsky.social/post/3m4zpvbpf3k2i📃Publication alert!! Congrats to the Krämer lab on their new publication: "Identification of a Proteolysis-Targeting-Chimera that Addresses Activated Checkpoint Kinase-1 Reveals its Non-Catalytic Functions in Tumor Cells" 🔎Read more about it here: https://onlinelibrary.wiley.com/doi/10.1002/anie.20251478807 Nov 2025 09:04 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m4zpvbpf3k2ihttps://bsky.app/profile/sfb1361.bsky.social/post/3m4bajxgsf22zWe’re excited to have Lorraine Symington and Stephen West as our keynote speakers - covering how cells repair DSBs during replication and how chromosomes are rebuilt via HR. IMB & SFB 1361 Conference, 10–13 March 2026. Registration is live! #ISC26DNArepair #IMBMainz28 Oct 2025 15:25 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m4bajxgsf22zhttps://bsky.app/profile/sfb1361.bsky.social/post/3m3cjqg3byc2kNew publication!! 📑 Congrats to the Ulrich and @hopfnerlab.bsky.social labs on their latest work exploring how the INO80 chromatin remodeller facilitates DNA damage bypass via postreplicative gap repair. 🔎Read the paper here: www.embopress.org/doi/full/10.1038/s44318-025-00580-416 Oct 2025 10:17 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m3cjqg3byc2khttps://bsky.app/profile/sfb1361.bsky.social/post/3m37rn6cyic2iRegistration is open! Join us at IMB Mainz from 10–13 March 2026 for the 2nd International IMB & SFB 1361 Conference on "The Evil Within: Regulation and Repair of Endogenous DNA Damage". Don't miss this conference and register now via www.sfb1361.de/dnarepairconf2026 #ISC26DNArepair #IMBMainz15 Oct 2025 08:00 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m37rn6cyic2ihttps://bsky.app/profile/sfb1361.bsky.social/post/3m2lzzzhznk2lIt is with deep sadness that we share the news of the unexpected passing of our dear colleague and associated member Dr Nard Kubben last week. We extend our heartfelt condolences to his family, friends, and all those who had the privilege of knowing him. [contains quote post or other embedded content]07 Oct 2025 11:37 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m2lzzzhznk2lhttps://bsky.app/profile/sfb1361.bsky.social/post/3m2lzvrannk2lPublication alert!!📑 Congratulations to the @hopfnerlab.bsky.social, @yilanfan.bsky.social and @filizkuybu.bsky.social on the great work! Read about it here: https://www.nature.com/articles/s41467-025-64082-x [contains quote post or other embedded content]07 Oct 2025 11:35 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3m2lzvrannk2lhttps://bsky.app/profile/sfb1361.bsky.social/post/3lz6xhvg2hc2uYesterday’s full-day workshop co-organised with @imbmainz.bsky.social focused on building a strategic approach to research funding for postdocs. We’re proud to stand behind our postdocs as they shape the future of research! #PAWde #PostdocAppreciationWeek2025 #IMBMainz19 Sep 2025 13:22 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3lz6xhvg2hc2uhttps://bsky.app/profile/sfb1361.bsky.social/post/3lxwqrlikhk2f📃Just published: new #SFB1361 publication by the Krämer and Christmann labs! The article focuses on how the deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2. Find out more here: 🔎 https://www.nature.com/articles/s41392-025-02369-703 Sep 2025 13:35 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3lxwqrlikhk2fhttps://bsky.app/profile/sfb1361.bsky.social/post/3lwgts4bwws2nWe’re excited to welcome Susanne Gerber from the University Medical Center Mainz as an associated member of the #SFB1361! 🎉 Her expertise in bioinformatics and cutting-edge nanopore sequencing protocols will advance genomic and epigenomic research within our network.15 Aug 2025 12:22 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3lwgts4bwws2nhttps://bsky.app/profile/sfb1361.bsky.social/post/3lvsx64xj3c2mWe‘re proud to share that our #SFB1361 PhD student, Yilan Fan from the @hopfnerlab.bsky.social, has been awarded a poster prize at the CNIO-CaixaResearch Frontiers Meeting “Machines on DNA and RNA: A Molecular Mechanistic Perspective“ held on 28-30 May 2025 in Madrid, Spain. Congrats! 🎉07 Aug 2025 14:29 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3lvsx64xj3c2mhttps://bsky.app/profile/sfb1361.bsky.social/post/3lsdlmrnbjs2dLast week our #SFB1361 members gathered in Würzburg to discuss and plan for the 3rd funding period. This 3-day retreat led to many fruitful discussions and fresh ideas! Now its time to put these ideas to work! 🔬⚗️🧬 #scientificretreat #planning #DNArepair24 Jun 2025 07:37 +0000at://did:plc:f323c2cty7isubf5msfofxxi/app.bsky.feed.post/3lsdlmrnbjs2d