developmental biology/human in vitro gametogenesis/human adrenal and gonadal development and regenerationhttps://bsky.app/profile/kotaro-sasaki.bsky.socialhttps://bsky.app/profile/kotaro-sasaki.bsky.social/post/3mhykgasfrk2zFeatured in Penn Today: our human adrenal organoid platform. Rather than modeling hormone output alone, we reconstruct progenitor-driven zonal architecture providing a new framework to study how stem cells build and maintain endocrine function. https://penntoday.upenn.edu/news/stress-tested-testing-stress-novel-organoid-models-how-adrenal-gland-develops26 Mar 2026 21:30 +0000at://did:plc:fciagpviyi33slcaijsfj2ik/app.bsky.feed.post/3mhykgasfrk2zhttps://bsky.app/profile/kotaro-sasaki.bsky.social/post/3mgdj4pa5sc2pThrilled to share our new paper in Cell Stem Cell! 🧬 We generated stem cell–derived human adrenal tissue with functional zonation, recapitulating key aspects of the adrenal cortex’s 3D architecture and steroidogenic activity. https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(26)00072-X Kudos to the entire team!05 Mar 2026 19:16 +0000at://did:plc:fciagpviyi33slcaijsfj2ik/app.bsky.feed.post/3mgdj4pa5sc2phttps://bsky.app/profile/kotaro-sasaki.bsky.social/post/3lrsp3e35as2hSynthetic and stem cell endocrinology: Join Our Team to Recreate the Human Adrenal Gland and hypothalamic-pituitary-adrenal Axis Using the Power of Stem Cells. t.co/1z16UstQqY17 Jun 2025 14:23 +0000at://did:plc:fciagpviyi33slcaijsfj2ik/app.bsky.feed.post/3lrsp3e35as2hhttps://bsky.app/profile/kotaro-sasaki.bsky.social/post/3lqgv6iyu3c2yThrilled to share our latest preprint! We have successfully reconstituted a human adrenal cortex from stem cells, achieving functional zonation both in vitro and in vivo. https://www.biorxiv.org/content/10.1101/2025.05.24.655925v131 May 2025 04:15 +0000at://did:plc:fciagpviyi33slcaijsfj2ik/app.bsky.feed.post/3lqgv6iyu3c2y