An International Journal of Translational Neuropsychiatry https://www.cambridge.org/core/journals/acta-neuropsychiatrica/information/about-this-journalhttps://bsky.app/profile/actaneuropsych.bsky.socialhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3mnqqqonjic2qA 25-year longitudinal birth cohort study from Estonia reveals how genes, biomarkers, environment, and family shape behavior, mental health, and life trajectories. Findings offer key insights into neurodevelopment, psychiatric risk! @neuropsychochem.bsky.social https://doi.org/10.1017/neu.2026.1007208 Jun 2026 03:33 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3mnqqqonjic2qhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3mkgfluww2c2nSome papers carry more than scientific weight: they carry legacy. This study honors a deeply respected contributor to Acta Neuropsychiatrica and a leading figure in psychiatry, whose impact continues to shape the field. https://doi.org/10.1017/neu.2026.1005926 Apr 2026 20:31 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3mkgfluww2c2nhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3mi4nwbrpuk2jHow effective are music-based interventions for mental health in young adults? In this systematic review of clin trials in young adults, found that music therapy, binaural beats & rhythm-based auditory stimulation are associated w/ moderate improvements across multiple domains:28 Mar 2026 12:43 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3mi4nwbrpuk2jhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3me7kd5v3bk2d🧠🧬 Autoimmunity as an underexplored contributor to neuropsychiatric symptoms in 22q11.2 deletion syndrome A recent study synthesizes evidence linking autoimmune processes to the neuropsychiatric phenotype observed in 22q11.2 deletion syndrome (22q11DS).06 Feb 2026 18:36 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3me7kd5v3bk2dhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3md3tz2vptk2zHow prevalent are behavioural addictions among adolescents? A newly published study in Acta Neuropsychiatrica suggests insights by examining multiple behavioral addictions simultaneously.23 Jan 2026 13:54 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3md3tz2vptk2zhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3mc3gsldaqk23Decision-making in Borderline Personality Disorder (BPD) in Social Context A recent fMRI study publishe in Acta Neuropsychiatrica used a multi-round Ultimatum Game to examine fairness, norm violations, and value processing in individuals with BPD. #fMRI #SocialCognition10 Jan 2026 16:32 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3mc3gsldaqk23https://bsky.app/profile/actaneuropsych.bsky.social/post/3maldg4uihk2tAs we approach the end of 2025, we would like to send a warm thank you to the entire Acta Neuropsychiatrica community —our dedicated authors, diligent reviewers & committed editorial board members. On behalf of the Acta Neuropsychiatrica and the board of the SCNP.22 Dec 2025 13:24 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3maldg4uihk2thttps://bsky.app/profile/actaneuropsych.bsky.social/post/3maefb6iph22k🧩Exosomes: A New Frontier in Understanding & Treating Autism Spectrum Disorder (ASD) How can they advance ASD research?19 Dec 2025 19:08 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3maefb6iph22khttps://bsky.app/profile/actaneuropsych.bsky.social/post/3m7b6w6oz6l2e🌍 From nomadic origins to modern stress: what can birds teach us about mental health? https://doi.org/10.1017/neu.2025.1004505 Dec 2025 19:12 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m7b6w6oz6l2ehttps://bsky.app/profile/actaneuropsych.bsky.social/post/3m65jprd7j22o🧠 Could psychedelics help rewire the brain–body disconnect? 💊 + 🧍‍♀️A new pilot study explores this question by investigating psilocybin-assisted therapy in Motor Functional Neurological Disorder (FND), pairing pharmacological and rehabilitative approaches.21 Nov 2025 14:49 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m65jprd7j22ohttps://bsky.app/profile/actaneuropsych.bsky.social/post/3m52ou3hkh22b🩺 Building Early Pain Literacy Pain-related knowledge can improve quality of life and satisfaction, and the sooner the better ✨In a new study, a pain neuroscience education (PNE) program significantly improved outcomes in adolescents with and without intellectual disabilities.07 Nov 2025 18:18 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m52ou3hkh22bhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3m46lpkt4u22o🍄 What does the evidence say on Psilocybin Therapy in Depression? 📄 A new PRISMA-guided systematic review analyzed 22 clinical studies, including randomized controlled + open-label trials. Populations included treatment-resistant depression and varied dosing and adjunctive protocols27 Oct 2025 14:07 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m46lpkt4u22ohttps://bsky.app/profile/actaneuropsych.bsky.social/post/3m3x4bl7wyk25🧩 Rethinking Schizophrenia Emerging evidence suggests schizophrenia has 2 biologically distinct forms: 🔹 Major Neurocognitive Psychosis (MNP) 🔹 Simple Neurocognitive Psychosis (SNP) Both differ in immune and metabolic pathways, especially in how the brain processes tryptophan (TRP)24 Oct 2025 14:42 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m3x4bl7wyk25https://bsky.app/profile/actaneuropsych.bsky.social/post/3m3f4mufdk22gNavigating the Use of Xanomeline/Trospium (Cobenfy/KarXT) KarXT marks a significant shift as the first muscarinic Our latest paper breaks down the key patient profiles that may benefit most from this novel mechanism of action: https://doi.org/10.1017/neu.2025.1003217 Oct 2025 11:00 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m3f4mufdk22ghttps://bsky.app/profile/actaneuropsych.bsky.social/post/3m2tnap5ztc2i🎤 Voice over for measuring the physiological stress response. What if the speech could be used as a digital biomarker of stress? Using a validated stress-induction paradigm, researchers analyzed vocal features in relation to salivary cortisol and state anger.10 Oct 2025 12:10 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3m2tnap5ztc2ihttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lzo2qvnaoc2aIs Clozapine use hindered?🚧A recent paper sheds light on how to transform care for treatment-resistant schizophrenia Clozapine initiation and maintenance are hampered by misconceptions about side effects and monitoring (e.g., hospitalization/frequent tests) 🩺📋, despite confidence in the guidelines25 Sep 2025 13:30 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lzo2qvnaoc2ahttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lz7mozgv6k2n🔬Molecular Mechanisms of Amisulpride New cell study reveals the complex molecular footprint of the antipsychotic amisulpride. 📊Scientists treated neuroblastoma cells with amisulpride and discovered it changes the levels of key genes and proteins involved in:👇19 Sep 2025 19:42 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lz7mozgv6k2nhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lyiobjsc322f📢Exciting news #CINP2026 in Glasgow will be a Joint Meeting of the Scandinavian College of Neuropsychopharmacology (SCNP) + the International College of Neuropsychopharmacology! Join us for this unique event which promises to be an outstanding meeting of science & collaboration @ijnp.bsky.social10 Sep 2025 16:39 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lyiobjsc322fhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3ly3qw6pyak22💊GLP-1 Agonists & Opioid Abuse New translational work examines whether GLP-1 receptor agonists(GLP-1 RAs) could support treatment and/or prevention in people living with opioid use disorder(OUD) 🛡️Early evidence suggests GLP-1 RA administration was linked to reduced risk of opioid overdose in humans05 Sep 2025 13:21 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3ly3qw6pyak22https://bsky.app/profile/actaneuropsych.bsky.social/post/3lxjwoh2wek2v🧠✨ Psychedelics & the Neuroimmune System A new review in Acta Neuropsychiatrica explores how 5-HT2A receptor psychedelics interact with the immune system, and how this interplay may also drive neuronal changes.29 Aug 2025 11:16 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lxjwoh2wek2vhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lwymdkkqqc2z🚨 Could AI Chatbots Worsen Mania in Bipolar Disorder? A striking editorial suggests that chatbots may mirror and amplify the elevated mood of users prone to mania, acting like a form of "emotional contagion." 🧠 Check the editorial at: https://doi.org/10.1017/neu.2025.10035 #DigitalMentalHealth #AIRegulation22 Aug 2025 13:56 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lwymdkkqqc2zhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lvvz6wnlxk2g🧩FGF19: Linking Smoke and Mental Health 🚬 Fibroblast growth factor 19 (FGF19) regulates a wide range of biological functions (energy homeostasis, proliferation, survival, and migration) and has an emerging role as an oncology target A recent study on FGF19 in depression and smoking revealed:08 Aug 2025 19:43 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lvvz6wnlxk2ghttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lve2ls7r3c22🛤️ "The path is known by asking those who have walked it before." — Zulu proverb (South Africa) 🧠 This new study in Acta Neuropsychiatrica examined modifiable & non-modifiable factors linked to mental health changes during COVID-19.01 Aug 2025 16:20 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lve2ls7r3c22https://bsky.app/profile/actaneuropsych.bsky.social/post/3lulgvavuhk24🌍🧠 #WorldBrainDay | July 22 Brain health is vital at every age. From early development to aging, protecting brain function improves lives globally. ➡ 1 in 8 people live with a mental disorder, often affecting cognition, emotion & behavior. #BrainHealthForAll #Neuropsychiatry22 Jul 2025 21:24 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lulgvavuhk24https://bsky.app/profile/actaneuropsych.bsky.social/post/3lu6rlvmcqk26A follow-up exome analysis of 270K UK #Biobank participants again found no gene-level associations with affective disorders. Even in severe cases needing specialist referral and in this large sample, rare variant effects are likely too small and spread across many genes.17 Jul 2025 20:31 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lu6rlvmcqk26https://bsky.app/profile/actaneuropsych.bsky.social/post/3ltpqeqtbnc2t🧠Is Internet Search a Proxy for Treatment? No, we’re not talking about 🍕restaurants near the Pentagon. But in a similar way, Google Trends mirrors real-world ADHD prescription patterns Researchers found that in Scandinavia (2010–2023) search trends correlate w/ADHD prescriptions https://doi.org/10.1017/neu.2025.2011 Jul 2025 20:59 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3ltpqeqtbnc2thttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lt63l7j7p226🧠 😞 Late-Life Depression (LLD) LLD is shaped by a complex interplay of biological, psychological, and social factors + distinct clinical and biological features.04 Jul 2025 20:31 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lt63l7j7p226https://bsky.app/profile/actaneuropsych.bsky.social/post/3ls24qoddtc2vEiC @wegener.bsky.social had the pleasure of welcoming the Associate Editor for the Special Content Section, Prof. Gin Malhi (University of Sydney), to the beautiful summer at Aarhus University.20 Jun 2025 13:16 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3ls24qoddtc2vhttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lq6jkw7pxk2c🧠New insights into the mechanism for the motor and #immune deficits of Kabuki syndrome Bapa mice show ↑striatal TH, GFAP, IBA-1—linking #dopaminergic hyperactivity & #neuroinflammation. The strain is a promising model to study motor & immune deficits https://doi.org/10.1017/neu.2025.1727 May 2025 20:26 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lq6jkw7pxk2chttps://bsky.app/profile/actaneuropsych.bsky.social/post/3lpkfrmxnxs2q🧠 Handling the Double-Edged Sword of Antipsychotics: Wielding Precision Psychiatry Antipsychotics like aripiprazole & risperidone are widely used—not just for psychosis but also mood & behavioral disorders. Yet, adverse effects may hinder outcomes. 🔄 #Psychiatry #Antipsychotics19 May 2025 20:25 +0000at://did:plc:g32adjderdrjzaejfdaskvav/app.bsky.feed.post/3lpkfrmxnxs2q