Freelance science journalist - I write about what works in biotech - and what doesn't.https://bsky.app/profile/cormacsheridan.bsky.socialhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3mo4jgo4syc2i@johncreedon.bsky.social Hi John, loved the Jimmy Crowley track & delighted to see the love & support for a national, regional & local treasure. Listening to his singing is an education in itself. Wishing the man himself the very best at this difficult time in his life.12 Jun 2026 19:54 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3mo4jgo4syc2ihttps://bsky.app/profile/cormacsheridan.bsky.social/post/3mnqbke5pds22https://www.europeanpressprize.com/article/what-the-wounds-are-telling-us/07 Jun 2026 23:01 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3mnqbke5pds22https://bsky.app/profile/cormacsheridan.bsky.social/post/3mcz6eqjuf22xGetting beyond the liver has been a key goal for developers of oligonucleotide-based drugs. For many tissues - notably the CNS, muscle & heart - antibody-oligonucleotide conjugates can elicit therapeutic effects well beyond those of unmodified siRNA or antisense drugs. https://www.nature.com/articles/s41587-025-02987-022 Jan 2026 12:21 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3mcz6eqjuf22xhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m7ajx6qa4k2yDogmatism, not data, drives RFK Jr.'s damaging anti-vax agenda. https://www.science.org/content/article/what-s-fuss-about-aluminum-vaccines05 Dec 2025 12:56 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m7ajx6qa4k2yhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m6upvs7bx22lSomething is rotten in the state of science publishing... As if the external attacks from RFK Jr. et al weren't enough, dodgy operators are undermining it from within. [contains quote post or other embedded content]30 Nov 2025 20:11 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m6upvs7bx22lhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m6oyqzc7mk2l#Measles deaths down 88% since 2000, says @who.int . Vaccines have saved almost 59m lives in this time - but cases are on the rise again - vigilance against the world's most contagious virus is essential. #vaccineswork https://www.who.int/news/item/28-11-2025-measles-deaths-down-88--since-2000--but-cases-surge28 Nov 2025 13:33 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m6oyqzc7mk2lhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m5lx3szw7s2lJust out in @natbiotech.nature.com - a deep dive into what's next in idiopathic pulmonary fibrosis after the approval of @boehringerglobal.bsky.social's Jascayd (nerandomilast). There's still huge scope for innovation here - & many good ideas being pursued. https://www.nature.com/articles/s41587-025-02908-114 Nov 2025 15:00 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m5lx3szw7s2lhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m5gnafpat22jGood piece by Eric Stokstad on an unusual and very damaging toxic algal bloom - we can expect more of these as #climatechange creates #ecosystems havoc https://www.science.org/content/article/australia-s-unprecedented-toxic-algal-bloom-has-surprise-culprit?et_rid=60656375&et_cid=578856712 Nov 2025 12:21 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m5gnafpat22jhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m4guhflgqc2oYou could equally argue that humans are the only irrational species. I have a lot of respect for the decision-making processes of other species. [contains quote post or other embedded content]30 Oct 2025 21:05 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m4guhflgqc2ohttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m3u7zoazp22n@tcddublin.bsky.social clinical trial shows repeated infusions of #ketamine of no benefit to patients hospitalised with #depression https://jamanetwork.com/journals/jamapsychiatry/fullarticle/284055223 Oct 2025 11:11 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m3u7zoazp22nhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m3sl4mjbv22v@johncreedon.bsky.social John, it's actually a murder of crows - but if there are only two or three it can be downgraded to an attempted murder ;)22 Oct 2025 19:24 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m3sl4mjbv22vhttps://bsky.app/profile/cormacsheridan.bsky.social/post/3m3fm27kfds2lMost transcription factors were historically considered undruggable. But some innovative biotechs are changing all that - & big pharma is starting to pay attention (and big bucks). Out now in @natbiotech.nature.com https://www.nature.com/articles/s41587-025-02862-y17 Oct 2025 15:36 +0000at://did:plc:i2vee7s4es3bj34d3klunfcd/app.bsky.feed.post/3m3fm27kfds2l