The Genetics Society of America is a professional scientific society representing genetics researchers and educators globally.https://bsky.app/profile/genetics-gsa.bsky.socialhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlygk6iymp2fNew research integrates molecular simulations with mutational profiling to discover the resistance mechanism of echinocandins—drugs used for the treatment of fungal infections. 💊 Read more in the May issue of #GENETICS:🔗 buff.ly/h2xXO6g 📷️ credit: Romain Durand, @christianlandry.bsky.social16 May 2026 18:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlygk6iymp2fhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mly7vq5bbn2fThe first genome-wide functional analysis of Cluster L1 mycobacteriophage LeBron in an overexpression screen identifies cytotoxic genes. Find out more in #G3journal: 🔗 buff.ly/KM79xDO16 May 2026 16:03 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mly7vq5bbn2fhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlvw6s7k3p2gA QTL analysis from @fcocubillosr.bsky.social lab for natural variation in maltose consumption in Saccharomyces eubayanus (a brewing #yeast 🍻 ) identifies loci associated with differences in maltose metabolism, which carries the transcriptional activator MAL33. More in #GENETICS: 🔗 buff.ly/BoZZutv15 May 2026 18:03 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlvw6s7k3p2ghttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlvffofo7t2yNew in #GENETICS from @triggerloop.bsky.social: A genome-wide screen using transcription start site(TSS) mapping in #yeast reveals that preinitiation complex mutants alter TSS usage globally across promoters, whereas chromatin and transcription elongation mutants had limited effects. buff.ly/g4ky5Do15 May 2026 13:03 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlvffofo7t2yhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mltmdtegue2bIt is no surprise that contamination leads to incorrect conclusions in population genetics studies. @audreykward.bsky.social, @mcmomany.bsky.social, @dbensasson.bsky.social caution that even low-level contamination has a greater impact on analyses than expected. More in #G3journal: buff.ly/kYFXQfM14 May 2026 20:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mltmdtegue2bhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlt74h3azc2u📢 NEW GENOME ALERT The first reference genome of a parasitic fly Istocheta aldrichi provides a crucial resource in conservation efforts, as it is used as a biological control agent for the invasive Japanese beetle in North America. Paper in #G3journal: 🔗 buff.ly/RJgwD0R14 May 2026 16:05 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlt74h3azc2uhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlqv5notpm2mA loss-of-function analysis suggests that Yaf9 is essential for survival when histone H4 acetylation is impaired, revealing a compensatory relationship between Yaf9 and histone H4 acetylation in #yeast. Learn more in #GENETICS: 🔗 buff.ly/zUwdveN13 May 2026 18:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlqv5notpm2mhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlqojxj6p72bOn this day in 1961, two research teams published back-to-back papers in Nature confirming the existence of mRNA—a breakthrough that transformed our understanding of how genetic information flows from DNA to proteins.13 May 2026 16:03 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlqojxj6p72bhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlqeit42yx2yA new study in #GENETICS developed algebraic derivations for the segregation variance in autotetraploid crops with a heterozygous genome and demonstrated its potential in predicting segregation variance in #potato #breeding programs. 🥔 🧬 🔗 buff.ly/EHc8eHw13 May 2026 13:04 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlqeit42yx2yhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlolfgqcak2uIn #GENETICS, a computational model builds genotype-phenotype associations across model organisms and analyzes whole-organism comorbidities associated with genes underlying non-obstructive azoospermia (NOA), the most severe form of male infertility. 🔗 buff.ly/WQvabcw12 May 2026 20:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlolfgqcak2uhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlo65t7slt2eLatest in #GENETICS: A gain-of-function genetic screen for the regulation of histone H1 function in #Drosophila identifies several factors that affect chromosome structure, histone H1 binding, and histone H1 exchange with greater impacts on genome organization and accessibility. 🔗 buff.ly/MujDw5H12 May 2026 16:05 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlo65t7slt2ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlluajeaou2z📢 NEW GENOME ALERT in #G3journal The New World screwworm, Cochliomyia hominivorax, is an obligate parasite of warm-blooded animals and a major pest of livestock and wildlife. Its improved genome offers better resolution of the sex chromosomes and updated genome annotations. 🔗 buff.ly/nPZvItR11 May 2026 18:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlluajeaou2zhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlldiybmp22eIn #GENETICS, @marbeitman.bsky.social et al. used #Drosophila hybrids to uncover new molecular and neural mechanisms underlying the evolution of #courtship behavior, highlighting how genetic and sensory inputs shape species-specific behavioral outcomes. 🔗 buff.ly/kq9JL6n11 May 2026 13:03 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlldiybmp22ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlgtan2fqg2gA comparison between two commonly used mutant screening methods in #Daphnia identifies the strengths and limitations of each approach in detecting #CRISPR-induced changes in target genes. Read more in the May issue of #G3journal: buff.ly/MscngSC 📷️ credit: Bret Coggins09 May 2026 18:01 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlgtan2fqg2ghttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlgmpbl7rp2eIn #G3journal, @wbooker.bsky.social and Daniel Schrider used simulations to understand the evolution of small diploid and autotetraploid crop populations and to identify the conditions that support the evolution of pseudo-overdominance. 🔗 buff.ly/ziFWhXM09 May 2026 16:04 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlgmpbl7rp2ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlejifdj552eDive deep into this new perspective piece in #GENETICS, emphasizing the limitations of classical genetics in deciphering genotype-phenotype relationships and the need for new experimental paradigms to understand context-dependent genetic effects. 🧬 🔗 buff.ly/VOi9xht08 May 2026 20:01 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlejifdj552ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mle4bvc6hb2fNew results in #GENETICS support the most parsimonious model of background selection, where partially recessive deleterious mutations and adaptation to captivity can explain the genetic diversity in #Drosophila experimental data better than models of overdominance. 🪰 🔗 buff.ly/c4nXbJy08 May 2026 16:05 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mle4bvc6hb2fhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlbz3wgjce2pNew findings in #GENETICS from @bendeskylab.com show that the conversion of dietary pro-vitamin A carotenoids to retinal by beta-carotene oxygenase 1 (bco1l) is essential for retinoic acid-dependent processes in larval and juvenile betta fish. 🐟️ 🧬 🔗 buff.ly/Dzx2NIH07 May 2026 20:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlbz3wgjce2phttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlbseybfcl2zWhy do pix-1 #Celegans mutants show variability in phenotype severity in muscles? 🪱 A new genetic mapping in #GENETICS reveals that an enhancer to the ipmk-1 gene contributes to phenotype severity by influencing the proper assembly of Integrin adhesion complexes in muscles. 🔗 buff.ly/qtBrXHw07 May 2026 18:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlbseybfcl2zhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mlbbn5jtmf2xA mutant analysis in #GENETICS uncovers a new role for the #Celegans TWK26 potassium channel in lipid homeostasis—where it promotes intestinal oligopeptide absorption in concert with the FLR4 protein kinase—controlling intestinal physiology and metabolism. @sarahtorzone.bsky.social buff.ly/TPlUTuV07 May 2026 13:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mlbbn5jtmf2xhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml7p7ctu5f2yOn the G3 cover: "A Bittersweet Symphony" Using a diverse cider germplasm from the USDA Malus collection, authors identified significant genetic markers for polyphenols, individual sugars, & malic acid. More⬇️🧵06 May 2026 22:00 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml7p7ctu5f2yhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml7hnagppz2eAt the Santeuil field C. elegans natural populations have been monitored for over a decade—there a stream meanders through the wood. Whole-genome sequencing data shows a tree-like haplotype network tracing the accumulation of mutations in selfing populations sampled along the stream across years. ⬇️🧵06 May 2026 19:45 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml7hnagppz2ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml73ifmpdi2zWhat does ancient DNA reveal about biological kinships? Read this exciting study in #GENETICS that used Exponential Random Graph models for correlates of relatedness, identifying evidence for female exogamy and the existence of an elite class in ancient Avar. buff.ly/aSPLOTg @brohrlach.bsky.social06 May 2026 16:07 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml73ifmpdi2zhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml4rgyaugl2xA longitudinal analysis published in #GENETICS highlights the central role of genetics in shaping dietary intervention outcomes, such as in intermittent fasting, in a mammalian model with physiological relevance to humans. #longevity #dietaryrestrcition 🔗https://buff.ly/lsvtZ6j05 May 2026 18:02 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml4rgyaugl2xhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml4kp34jxd2e🪰 We asked what you’re looking forward to at #Dros27 — connection stood out! As organizer @seyeonchung.bsky.social shared, the fly community is welcoming & supportive. One of the best parts of this meeting is reconnecting with friends & meeting new faces. So, who are you excited to connect with? ⬇️05 May 2026 16:01 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml4kp34jxd2ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml4apr4f3g2eNew in #GENETICS: @ornacf.bsky.social and the team discovered that Kar4—a putative transcription factor required for efficient mating in the budding #yeast Saccharomyces cerevisiae—increases the DNA-binding specificity of Ste12 globally. 🔗 buff.ly/q5ncnCV05 May 2026 13:03 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml4apr4f3g2ehttps://bsky.app/profile/genetics-gsa.bsky.social/post/3ml2hluvveb2fThis new study in #GENETICS establishes #Celegans as a model for #Hippo signaling, identifying Hippo-dependent and -independent signals that control WTS-1 in epithelia and intestine, respectively. 🪱 🔗 buff.ly/cdGmEPa04 May 2026 20:00 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3ml2hluvveb2fhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mkzuuovik62zNew research in #GENETICS shows how Rho GTPase signaling regulates synaptic transmission in the #Celegans egg-laying circuit, identifying Rho-1 signals downstream of Trio RhoGEF to promote egg laying. 🔗 buff.ly/YESIYAC04 May 2026 14:25 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mkzuuovik62zhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mkv7ylnfe32b📢 NEW GENOME ALERT @laramiemckenna.bsky.social and the team present a highly contiguous, chromosome-scale, haplotype-resolved genome assembly for the southern live oak. Discover the American Campus Tree Genomes program in this #G3journal paper: 🔗 buff.ly/AVKatnX02 May 2026 18:01 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mkv7ylnfe32bhttps://bsky.app/profile/genetics-gsa.bsky.social/post/3mkuzgcl36q2eLearn about a new simulation methodology in #G3journal that is designed to increase recombination rate in #breeding programs and to determine the effect of recombination on genetic gain using phenotypic and genomic selection. 🔗 buff.ly/vQrCTBr02 May 2026 16:04 +0000at://did:plc:ilj5s34teeu6ssmcmljbmfg7/app.bsky.feed.post/3mkuzgcl36q2e