The official journal of the American Society for Investigative Pathobiology, publishing mechanistic discoveries in basic and translational pathobiology.https://bsky.app/profile/ajpathology.bsky.socialhttps://bsky.app/profile/ajpathology.bsky.social/post/3mttxvun4y52cAutocrine TGF-β signaling promotes cell motility and chemokine secretion in an angiomyolipoma-derived cell model of lymphangioleiomyomatosis. Authors from @jagiellonskiuni.bsky.social Full text: https://loom.ly/yq6zEwM https://ajp.amjpathol.org/article/S0002-9440(25)00182-8/fulltext24 Aug 2026 18:51 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mttxvun4y52chttps://bsky.app/profile/ajpathology.bsky.social/post/3mtoecrto4a2d#LegacyContent: The Long Noncoding RNA TUG1 Is Down-Regulated in Osteonecrosis of the Femoral Head and Enhances the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Stimulating the Wnt/β-Catenin Pathway #OpenArchive: https://loom.ly/25ajqqA https://ajp.amjpathol.org/article/S0002-9440(25)00183-X/fulltext22 Aug 2026 13:17 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtoecrto4a2dhttps://bsky.app/profile/ajpathology.bsky.social/post/3mtlv37bmgi2b#LegacyContent: Mitochondrial protease AFG3L2 inhibits ferroptosis of intestinal epithelial cells through PPARA/GPX4 signaling pathway to improve experimental enteritis. Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(25)00184-1/fulltext21 Aug 2026 13:39 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtlv37bmgi2bhttps://bsky.app/profile/ajpathology.bsky.social/post/3mtjqpgndb52nDiagnosis of #Leukemia from Bone Marrow Flow Cytometry Data Using #DeepLearning and Explainable Artificial Intelligence Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00097-0/fulltext20 Aug 2026 17:15 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtjqpgndb52nhttps://bsky.app/profile/ajpathology.bsky.social/post/3mthijzymew2t#LegacyContent: Exploratory study of prognostic plasma biomarkers in patients with pulmonary arterial hypertension. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00181-6/fulltext19 Aug 2026 19:44 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mthijzymew2thttps://bsky.app/profile/ajpathology.bsky.social/post/3mtf2khibau27Read the latest #PressRelease from @ajpathology.bsky.social: Novel AI Model Accurately Detects Key Gene Mutations and Predicts Biomarkers Across 32 Cancer Types Read the full release here: https://loom.ly/Wv0wJ-I18 Aug 2026 20:28 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtf2khibau27https://bsky.app/profile/ajpathology.bsky.social/post/3mtexabwaor2xColonic Goblet Cell Activity and Proinflammatory Responses Are Spatially Regulated in the Colon in Citrobacter rodentium Infections. Authors from @ucalgary.bsky.social. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00128-8/fulltext18 Aug 2026 19:29 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtexabwaor2xhttps://bsky.app/profile/ajpathology.bsky.social/post/3mtedkukfxt2j#CallforPapers @ajpathology.bsky.social seeks original research related to mechanistic advances in organ to organ crosstalk in disease for an upcoming theme issue. Deadline 11/30/2026. Submission is free and can be completed online: https://loom.ly/GTKfx4o18 Aug 2026 13:37 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtedkukfxt2jhttps://bsky.app/profile/ajpathology.bsky.social/post/3mtcrxdfcrk2g#LegacyContent: FKBP10 Silencing Alleviates Gluteal Muscle Contracture by Inhibiting Fibrosis and Restoring Autophagy via HSP47/SMAD3 Pathway Inactivation. Authors from the University of South China. Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(25)00146-4/fulltext17 Aug 2026 22:49 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mtcrxdfcrk2ghttps://bsky.app/profile/ajpathology.bsky.social/post/3mt2vybom342d#ArticleinPress: PI3K Signaling Enhances Intestinal Crypt Epithelial Cell Recovery after Radiation. Authors from @universityofky.bsky.social. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00151-8/fulltext14 Aug 2026 19:40 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mt2vybom342dhttps://bsky.app/profile/ajpathology.bsky.social/post/3mt2axwvhhc2nGene Contribution of Streptococcus dysgalactiae Subspecies equisimilis, an Emerging Pathogen, to Experimental Primate Necrotizing Myositis. Authors from @houstonmethodist.bsky.social. Full text: https://loom.ly/deKvsHQ14 Aug 2026 13:24 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mt2axwvhhc2nhttps://bsky.app/profile/ajpathology.bsky.social/post/3msxrhfxmkt2n#CallforPapers @ajpathology.bsky.social seeks original research related to mechanistic advances in organ to organ crosstalk in disease for an upcoming theme issue. Deadline 11/30/2026. Submission is free and can be completed online: https://loom.ly/GTKfx4o13 Aug 2026 13:41 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msxrhfxmkt2nhttps://bsky.app/profile/ajpathology.bsky.social/post/3msvtnfaj4d2sComplement C3a Receptor 1 and Complement C5a Receptor 1 Are Dual Contributors of Chronic-Plus-Binge–Induced Hepatic Inflammation and Injury. Authors from @cuanschutz.bsky.social. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00156-2/fulltext 12 Aug 2026 19:14 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msvtnfaj4d2shttps://bsky.app/profile/ajpathology.bsky.social/post/3msvhee36ng2z#LegacyContent: IGF2BP2 Drives Subchondral Bone Damage in Temporomandibular Joint Osteoarthritis through PPARγ/C-FOS-regulated Dual Pathways: NFATC1 Signaling and ATG16L2-Mediated Autophagy. Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(25)00149-X/fulltext12 Aug 2026 15:35 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msvhee36ng2zhttps://bsky.app/profile/ajpathology.bsky.social/post/3mst7witd6h2vSIRPα Cleavage Is Associated with Inflammatory Response, Corticosteroid Nonresponse, and Worse Prognosis in Clinical and Preclinical Models of Alcohol-Associated Hepatitis. Full text: https://loom.ly/h3OyUnw11 Aug 2026 18:16 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mst7witd6h2vhttps://bsky.app/profile/ajpathology.bsky.social/post/3msq7dfrcpb2p#LegacyContent: Notch signaling aggravates Helicobacter pylori-induced inflammation by promoting macrophage activation and pro-inflammatory Th1/Th17 responses. Authors from Southern Medical University. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00148-8/fulltext10 Aug 2026 13:28 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msq7dfrcpb2phttps://bsky.app/profile/ajpathology.bsky.social/post/3msj7lovytn2g#LegacyContent: Identification of a growth-promoting gene cluster in the region 2q24 as a driver of tumorigenesis in childhood hepatoblastoma. Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(25)00147-6/fulltext07 Aug 2026 18:44 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msj7lovytn2ghttps://bsky.app/profile/ajpathology.bsky.social/post/3msg5shkmwk27Hepatocyte-specific PPARγ Deletion Uncovers Role of an Antagonistic PPARγ–HNF4α Transcriptional Axis in Metabolic Dysfunction–Associated Steatotic Liver Disease Progression. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00137-9/fulltext06 Aug 2026 13:34 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msg5shkmwk27https://bsky.app/profile/ajpathology.bsky.social/post/3mseapzhzpm2j#ArticleinPress: SARS-CoV-2, the human placenta, and adverse perinatal outcomes. Authors from @upenn.edu. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00150-6/fulltext05 Aug 2026 19:21 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mseapzhzpm2jhttps://bsky.app/profile/ajpathology.bsky.social/post/3msbfflkj7g2v#CallforPapers @ajpathology.bsky.social seeks original research related to mechanistic advances in organ to organ crosstalk in disease for an upcoming theme issue. Deadline 11/30/2026. Submission is free and can be completed online: https://loom.ly/GTKfx4o04 Aug 2026 16:06 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msbfflkj7g2vhttps://bsky.app/profile/ajpathology.bsky.social/post/3msb5wlptda2m#LegacyContent: #AJPCentennial Guest Editorial: Discovery and Mechanistic Insights into Vascular Permeability Factor/Vascular Endothelial Growth Factor through the Work of Harold F. Dvorak and Ann M. Dvorak. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00145-2/fulltext04 Aug 2026 13:53 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3msb5wlptda2mhttps://bsky.app/profile/ajpathology.bsky.social/post/3ms776iomg52vDual Immune Lineage Activation Underlies Systemic Immunopathology in Acute-on-Chronic Liver Failure. From @asipath.bsky.social member Bilon Khambu and authors from @tulaneu.bsky.social #OpenAccess: https://loom.ly/xw2Bris03 Aug 2026 19:10 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3ms776iomg52vhttps://bsky.app/profile/ajpathology.bsky.social/post/3ms6lfj7vk72jNew month, new #LegacyContent. The August 2025 issue of @ajpathology.bsky.social is now fully free in the #OpenArchive! Full issue: https://loom.ly/OrDq7eg On the cover: Schematic mask of collagen VII and surrounding cells in idiopathic pulmonary fibrosis.03 Aug 2026 13:16 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3ms6lfj7vk72jhttps://bsky.app/profile/ajpathology.bsky.social/post/3ms4khoukn227#ArticleinPress: APOE4 Increases Systemic Inflammation and Alters Metabolic and Neuroprotective Pathways following Multiagent Chemotherapy in Older Human APOE Knock-In Mice. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00162-8/fulltext02 Aug 2026 17:54 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3ms4khoukn227https://bsky.app/profile/ajpathology.bsky.social/post/3mrzn57o7uy2v#ArticleinPress: Macrophage Polarization and Spatial Architecture Characterize the Tumor Immune Microenvironment and Prognosis in Hepatoblastoma. Authors from @helsinki.fi #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00164-1/fulltext01 Aug 2026 14:03 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mrzn57o7uy2vhttps://bsky.app/profile/ajpathology.bsky.social/post/3mrxd3jaobi22#ArticleinPress: Low-Dose Radiotherapy Attenuates Pulmonary Granulomas Involving Ataxia-Telangiectasia Mutated–Dependent Modulation of the Interferon-β Response: A Host-Directed Therapeutic Strategy for Tuberculosis. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00163-X/fulltext31 Jul 2026 15:58 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mrxd3jaobi22https://bsky.app/profile/ajpathology.bsky.social/post/3mrv3kfzhj724The August issue of @ajpathology.bsky.social is now live! Full issue: https://ajp.amjpathol.org/issue/S0002-9440(25)X0010-9 On the cover: Immunofluorescence staining for pluripotency markers in liver cancer stem cells.30 Jul 2026 18:38 +0000at://did:plc:j2o7vyu52ybb6peya43yvlqd/app.bsky.feed.post/3mrv3kfzhj724