<?xml version="1.0" encoding="UTF-8"?>
<rss version="2.0"><channel><description>Math, medicine and drug design - mainly interested in early onset Parkinons Disease, but not exclusively&#xA;&#xA;🌉 bridged from ⁂ https://mathstodon.xyz/@fckprknsns, follow @ap.brid.gy to interact</description><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy</link><title>@fckprknsns.mathstodon.xyz.ap.brid.gy - F*ck Parkinsons!</title><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mkwtj6wcwoi2</link><description>RE: https://ieji.de/@lesezeichen/116507577424426219&#xA;&#xA;What LLMs are really good at: Extracting infromation from the input data you give it and rephrasing it in natural language. E.g. if you prompt it with a knwoledge graph, a long article, a collection of books and ask a specific quesion about […]&#xA;https://mathstodon.xyz/@fckprknsns/116509914332651956</description><pubDate>03 May 2026 09:23 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mkwtj6wcwoi2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mkwt7z2aevg2</link><description>RE: https://hachyderm.io/@BenjaminHCCarr/116507805024722965&#xA;&#xA;Pretty cool stuff&#xA;https://hachyderm.io/users/BenjaminHCCarr/statuses/116507805024722965</description><pubDate>03 May 2026 09:18 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mkwt7z2aevg2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mkv2drsapqk2</link><description>RE: https://mastodon.social/@SteveThompson/116505558201679888&#xA;&#xA;This is really good news. Sounds very promising.&#xA;https://mastodon.social/users/SteveThompson/statuses/116505558201679888</description><pubDate>02 May 2026 16:20 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mkv2drsapqk2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mkuifqwsy2p2</link><description>RE: https://hachyderm.io/@baillehache_pascal/116503369993521453&#xA;&#xA;Explaining that genetics is complex is incredibly difficult with words, but this image illustrates it quite well.&#xA;https://hachyderm.io/users/baillehache_pascal/statuses/116503369993521453</description><pubDate>02 May 2026 10:59 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mkuifqwsy2p2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mkmluaewpui2</link><description>&#34;Veteran men reported greater average frequency of ACEs than nonveteran men (2.7 ACEs vs. 2.3 ACEs, respectively, p&lt;.001); 11.1% of veteran men indicated &gt;6 ACEs compared to 7.3% of nonveteran men (p&lt;.001). Veteran women reported greater average frequency of ACEs than nonveteran women (3.1 ACEs […]&#xA;https://mathstodon.xyz/@fckprknsns/116486856635468640</description><pubDate>29 Apr 2026 07:39 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mkmluaewpui2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mkmigryb3tr2</link><description>Today I learned about the ACE Score (Adverse Childhood Experiences), that gives a number from 1 to 10 which provides a simple sceening tool for childhood trauma. A higher ACE Score corresponds with a higher risk of health, social, and emotional problems. It also correlates with crime rates and […]&#xA;https://mathstodon.xyz/@fckprknsns/116486617286768845</description><pubDate>29 Apr 2026 06:38 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mkmigryb3tr2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mg34ialnyha2</link><description>The world around us is&#xA;of baffling complexity and the most obvious fact about it is that we cannot predict the future.</description><pubDate>02 Mar 2026 11:08 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mg34ialnyha2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mk5waydv5ba2</link><description>[&#34;AI&#34;, QUESTION about (non-) determinism of LLMs]&#xA;&#xA;RE: https://mathstodon.xyz/@fckprknsns/116449672042638891&#xA;&#xA;Actually that is still an open question in my mind: *Why* are LLMs not deterministic? I struggle to understand that. Given everything I know about how computers and LLMs work my […]&#xA;&#xA;[contains quote post or other embedded content]</description><pubDate>23 Apr 2026 11:36 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mk5waydv5ba2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mk43fxark6f2</link><description>[&#34;AI&#34;]&#xA;&#xA;I would like to propose the terminology of &#34;deterministic software&#34; versus &#34;non-deterministic software&#34;, in order to avoid confusion about whet is currently mostly refered to as &#34;artificial intielligence&#34;. The more I learn about LLMs, the more I try to avoid the terminology of […]&#xA;https://mathstodon.xyz/@fckprknsns/116449672042638891</description><pubDate>22 Apr 2026 18:03 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mk43fxark6f2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mhxgqqa4vaa2</link><description>LLM-Agents are opening up totally novel ways of interacting with scientific literature. Reading a paper is one thing. Creating knowlede based graphs based on hundrets of papers and looking at visualizations showing structures in that is a totally different thing. Automating this process makes […]&#xA;https://mathstodon.xyz/@fckprknsns/116295095625185131</description><pubDate>26 Mar 2026 10:52 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mhxgqqa4vaa2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mglarypcuxn2</link><description>&#34;Her final novel, published shortly before her diagnosis, is widely considered to exhibit signs of cognitive decline.&#34;&#xA;&#xA;Ouch. Imagine the critizism of your novel is that it is proof of your post-mortal Alzheimers Diagnosis. That is very harsh criticism. Good the poor author does not have to read […]&#xA;https://mathstodon.xyz/@fckprknsns/116195596948905987</description><pubDate>08 Mar 2026 21:08 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mglarypcuxn2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mgaedseruxp2</link><description>Absolute pitch accessible to everyone by turning off part of the brain?&#xA;&#xA;https://centreforthemind.com/publications/AbsolutePitch.pdf&#xA;&#xA;- absolute pitch is rare 1/10000&#xA;- likely all infants have absolute pitch&#xA;- absolute pitch dissapears with aquiring language&#xA;- all musical autistic savants have […]&#xA;https://mathstodon.xyz/@fckprknsns/116171077468312823</description><pubDate>04 Mar 2026 13:12 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mgaedseruxp2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mg5ysgl72wc2</link><description>Joy Milne, a Super Smeller whose husband Les was diagnosed with PD in 1986, has demonstrated a unique ability to detect PD by odor.</description><pubDate>03 Mar 2026 14:40 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mg5ysgl72wc2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mg34ialnyha2</link><description>The world around us is&#xA;of baffling complexity and the most obvious fact about it is that we cannot predict the future.</description><pubDate>02 Mar 2026 11:08 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mg34ialnyha2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfrkutp42qz2</link><description>This seems like Landauers Principle has been verified in an experment. This means there is indeed a hard limit on how effective computers can get.&#xA;&#xA;On the Wikipedia it says that: &#34;As of 2012, modern computers use about a billion times as much energy per operation.&#34;&#xA;&#xA;Computers became a lot more […]&#xA;https://mathstodon.xyz/@fckprknsns/116137760134527715</description><pubDate>26 Feb 2026 15:59 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfrkutp42qz2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfosndejivg2</link><description>This is a pretty neat way to explain how Alzheimers works by comparing it to neuronal networks. The memory is not gone, it just becomes harder to access.&#xA;&#xA;https://youtu.be/o_ZuWbX-CyE?t=1712</description><pubDate>25 Feb 2026 13:40 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfosndejivg2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfnbua6eh5u2</link><description>[entropy, notes]&#xA;&#xA;Since I few years now I have the idea in the back of my head to write some kind of essay about entropy one day. Now feels like a good time to do that- And since writing long texts is hard, I am going to write it bit by bit in the form of a thread here so you can follow my […]&#xA;https://mathstodon.xyz/@fckprknsns/116128043672222500</description><pubDate>24 Feb 2026 22:48 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfnbua6eh5u2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfmxhvzvgof2</link><description>If I understand this correctly than the main thesis of this paper is that Entropy in itself makes the creation of life from not living matter reasonably probable because living organisms do increase entropy quicker than dead matter and therefore there is some kind of natural drive in the […]&#xA;https://mathstodon.xyz/@fckprknsns/116127387447836425</description><pubDate>24 Feb 2026 20:01 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfmxhvzvgof2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mflrfkjz2662</link><description>every scientist needs a librarian!&#xA;&#xA;https://www.nature.com/articles/d41586-026-00568-y</description><pubDate>24 Feb 2026 08:40 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mflrfkjz2662</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfgssh5saiy2</link><description>Another interesting drug that is used in the treatment of PD is Apomorphine. And again this drug was initially found in a plant - the one commonly known as the blue lotus. A plant which has been historically used for medical purposes for thousands of years.&#xA;&#xA;https://en.wikipedia.org/wiki/Apomorphine</description><pubDate>22 Feb 2026 09:22 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfgssh5saiy2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mffuirmf2mm2</link><description>TL;DR: Women with greater dietary nicotine intake had a lower risk of PD than those with lower intake.&#xA;&#xA;What surprizes me most about this is that peppers apparently contain enough nicotine to have a measurable effect on PD.&#xA;&#xA;https://pmc.ncbi.nlm.nih.gov/articles/PMC7528555/</description><pubDate>22 Feb 2026 00:19 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mffuirmf2mm2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mffqfd5cgdh2</link><description>RE: https://loops.video/v/dS9lP2vG8_&#xA;&#xA;Please, let&#39;s cure neurodegenerative diseases with AI instead of using it for unsolicited virtual breast enhancements.&#xA;https://loops.video/ap/users/82408605504114688/video/249427909695939135</description><pubDate>21 Feb 2026 23:06 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mffqfd5cgdh2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mffkd6n2jhi2</link><description>[question, caffeine]&#xA;&#xA;I just hered someone claim &#34;caffeine is a habit enhancer&#34;. Does anybody have an idea what that might mean? Or even some references to this?</description><pubDate>21 Feb 2026 21:17 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mffkd6n2jhi2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfealpekxtu2</link><description>If one has a hammer everything starts looking like a nail. And if you have LLM&#39;s everything looks like a problem that can be done by autocomplete.&#xA;&#xA;https://www.theregister.com/2026/02/18/generating_passwords_with_llms/&#xA;&#xA;TL;DR Do NOT use LLM&#39;s to generate passwords!</description><pubDate>21 Feb 2026 08:51 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfealpekxtu2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfbvrkop6cx2</link><description>The term &#34;Parkinsons Disease&#34; first spiked in litterature in the 1860&#39;s / 1870&#39;s - that makes a lot of sense. While the orriginal essay on by James Parkinson was bublished in 1817, the term Parkinsons Disease was only coined after his death by the neurologist […] &#xA;&#xA;[Original post on mathstodon.xyz]</description><pubDate>20 Feb 2026 10:32 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfbvrkop6cx2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mfbsqgsxw5u2</link><description>It is interesting to see how the term &#34;hallucination&#34; changed it&#39;s context with the upcoming of neural networks. The term used to be entirely medical, and it used to be a phenomenon with a clearly negative connotation.&#xA;&#xA;Now, depnding on the context the […] &#xA;&#xA;[Original post on mathstodon.xyz]</description><pubDate>20 Feb 2026 09:37 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mfbsqgsxw5u2</guid></item><item><link>https://bsky.app/profile/fckprknsns.mathstodon.xyz.ap.brid.gy/post/3mf6hduwry5q2</link><description>The drug Pimavanserin is approved for treatment of Parkinons Disease Psychosis since 2016 in the USA, but it is currently not available in the EU. It works by blocking serotonine receptors.&#xA;&#xA;https://en.wikipedia.org/wiki/Pimavanserin</description><pubDate>19 Feb 2026 01:35 +0000</pubDate><guid isPermaLink="false">at://did:plc:j4c2yolkzhyfwkimz6tocghq/app.bsky.feed.post/3mf6hduwry5q2</guid></item></channel></rss>