Interested in comparative & functional microbial genomics, RNA biology, native CRISPR systems, cyanobacteria, plant evolution & regulation of photosynthesishttps://bsky.app/profile/cyanolab.bsky.socialhttps://bsky.app/profile/cyanolab.bsky.social/post/3m7akakud6c2eA new + interesting paper on the guanidine riboswitch in Synechocystis and other cyanobacteria: "Deciphering guanidine assimilation and ri"boswitch-based gene regulation in cyanobacteria for synthetic biology applications" | PNAS https://www.pnas.org/doi/10.1073/pnas.2519335122#abstract05 Dec 2025 13:01 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3m7akakud6c2ehttps://bsky.app/profile/cyanolab.bsky.social/post/3lzqtqrrxfk2dRiding a train in China, returning from the ISPP 2025 and the Green Carbon conference.26 Sep 2025 16:03 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lzqtqrrxfk2dhttps://bsky.app/profile/cyanolab.bsky.social/post/3lzqtbi3jcc2b„RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics dataset“ rdcu.be/eImcr : 11 authors from 3 labs. Many thanks to all for making this possible! https://rdcu.be/eImcr26 Sep 2025 15:55 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lzqtbi3jcc2bhttps://bsky.app/profile/cyanolab.bsky.social/post/3lzqt3dhogk2bHow to search for unknown RNA-binding proteins? We did GradR in the cyanobacterium Synechocystis 6803. And now our paper „RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics dataset“ is finally out in Nature Communications, here: rdcu.be/eImcr . https://rdcu.be/eImcr26 Sep 2025 15:51 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lzqt3dhogk2bhttps://bsky.app/profile/cyanolab.bsky.social/post/3lwduotxh6k2uRiding a train in Lithuania.14 Aug 2025 08:00 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lwduotxh6k2uhttps://bsky.app/profile/cyanolab.bsky.social/post/3lsjbw633622tRNA-binding proteins and photosynthesis: The RRM domain–containing protein Rbp3 interacts with ribosomes and the 3’ ends of mRNAs encoding photosynthesis proteins | PNAS https://www.pnas.org/doi/10.1073/pnas.250627512226 Jun 2025 13:59 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lsjbw633622thttps://bsky.app/profile/cyanolab.bsky.social/post/3lsjbleldxk24Inorganic carbon levels regulate growth via SigC signaling cascade in cyanobacteria - Kurkela - New Phytologist - Wiley Online Library https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.7032826 Jun 2025 13:53 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lsjbleldxk24https://bsky.app/profile/cyanolab.bsky.social/post/3lsb4ok3lf22gHow are fully submerged algae efficiently fixing carbon? All organisms performing oxygenic photosynthesis fix CO2 in the Calvin–Benson–Bassham cycle using RubisCO. But aquatic organisms have a challenge.23 Jun 2025 08:04 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lsb4ok3lf22ghttps://bsky.app/profile/cyanolab.bsky.social/post/3lji2eedpxk2pTIGR-Tas: A new family of modular RNA-guided DNA-targeting systems in prokaryotes and their viruses: https://www.science.org/doi/10.1126/science.adv978903 Mar 2025 13:24 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lji2eedpxk2phttps://bsky.app/profile/cyanolab.bsky.social/post/3lhivbflvpc26Why did chloroplasts retain some genes from their free-living ancestors rather than transferring all of them to the nucleus following endosymbiosis? We suggest that mRNA targeting might play a role. https://www.sciencedirect.com/science/article/pii/S136013852400267X?via%3Dihub06 Feb 2025 10:35 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lhivbflvpc26https://bsky.app/profile/cyanolab.bsky.social/post/3lgnksmpjkc2aMulticellularity is a key feature of complex life, but how to study multicellularity in bacteria and at the single cell level? Use advanced microscopy, MS imaging, flow cytometry, spatial and single-cell transcriptomics, advanced microfluidics and more. See here: https://journals.asm.org/doi/10.1128/mmbr.00138-2426 Jan 2025 13:46 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lgnksmpjkc2ahttps://bsky.app/profile/cyanolab.bsky.social/post/3ldpunatxks2gThe conformational space of RNase P RNA in solution using atomic force microscopy: https://www.nature.com/articles/s41586-024-08336-6#article-info20 Dec 2024 07:32 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3ldpunatxks2ghttps://bsky.app/profile/cyanolab.bsky.social/post/3ldoe42fqtc2aNot all bacteria, even of a single species, are created equal. Nor are they always unicellular. Some cyanobacteria develop heterocysts and fix nitrogen. GradR/R-DeeP analysis identified new RNA-binding proteins. Some were previously known for other functions. Others were completely uncharacterized.19 Dec 2024 17:03 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3ldoe42fqtc2ahttps://bsky.app/profile/cyanolab.bsky.social/post/3ldodbosrxk2aR-DeeP/TripepSVM identifies the RNA-binding OB-fold-like protein PatR as regulator of heterocyst patterning. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1247/792852319 Dec 2024 16:49 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3ldodbosrxk2ahttps://bsky.app/profile/cyanolab.bsky.social/post/3ldbfhth7jc2rISPP-18, the "International Symposium on Phototrophic Prokaryotes" will take place September 8-12, 2025. This is the best conference in the world to learn about recent research in photosynthetic prokaryotes. Only every 3 years. Registration for ISPP-18 is now open. ispp2025-qingdao.com https://ispp2025-qingdao.com14 Dec 2024 13:23 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3ldbfhth7jc2rhttps://bsky.app/profile/cyanolab.bsky.social/post/3ld6u6ubwms26How Small Proteins Adjust the Metabolism of Cyanobacteria Under Stress: https://onlinelibrary.wiley.com/doi/10.1002/bies.20240024513 Dec 2024 13:09 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3ld6u6ubwms26https://bsky.app/profile/cyanolab.bsky.social/post/3lcrx47wxqk25Cytosine N4-methylation by the DNA methyltransferase M.Ssp6803II is required for the proper expression level of protoporphyrinogen IX oxidase, HemJ. All details in our new paper in DNA Research: https://academic.oup.com/dnaresearch/advance-article/doi/10.1093/dnares/dsae035/7918679?utm_source=advanceaccess&utm_campaign=dnaresearch&utm_medium=email08 Dec 2024 09:56 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lcrx47wxqk25https://bsky.app/profile/cyanolab.bsky.social/post/3lcfqhgk4ys2sThe secrets of RNase P. This endoribonuclease is ubiquitous, but only in bacteria it is a ribozyme. We have characterized Ssr1238, a YlxR/DUF448 family protein to interact with the RNase P RNA in cyanobacteria. Details in our new paper: https://www.tandfonline.com/doi/full/10.1080/15476286.2024.2429230#abstract03 Dec 2024 13:25 +0000at://did:plc:js2qeigavgxxe4himigposce/app.bsky.feed.post/3lcfqhgk4ys2s