Scientist, Field: DNA replication, Mutagenesis, Genome stabilityhttps://bsky.app/profile/yasudaigaku.bsky.socialhttps://bsky.app/profile/yasudaigaku.bsky.social/post/3mgml7ncnrk2nI have been thinking about how to make our genomic data easily accessible to the public, and I am now testing Amazon Web Services. On this server, I have set up JBrowse (a type of genome browser) with datasets from human Polymerase usage sequencing (Pu-seq, Koyanagi et al Nat Commun 2022). https://cgd-daigaku-lab.s3.ap-northeast-1.amazonaws.com/jbrowse/index.html09 Mar 2026 09:47 +0000at://did:plc:knpfv4wvthbfsog5cebfifig/app.bsky.feed.post/3mgml7ncnrk2nhttps://bsky.app/profile/yasudaigaku.bsky.social/post/3mgmkgmp7j22nThe collaboration with the Taka Nojima lab (Kyushu University) and the Michael Tellier lab (University of Leicester) was published in EMBO Reports! We contributed to this work by analysing the effect of transcription termination defects on DNA replication. https://link.springer.com/article/10.1038/s44319-026-00700-z09 Mar 2026 09:33 +0000at://did:plc:knpfv4wvthbfsog5cebfifig/app.bsky.feed.post/3mgmkgmp7j22nhttps://bsky.app/profile/yasudaigaku.bsky.social/post/3lymuri2wbc26Our preprint on Pol-η usage during genome replication has been uploaded. It addresses the biased use of Pol-η in the lagging strand and late-replicating regions, which may be correlated with cancer mutagenesis. https://www.biorxiv.org/content/10.1101/2025.09.10.675280v112 Sep 2025 08:46 +0000at://did:plc:knpfv4wvthbfsog5cebfifig/app.bsky.feed.post/3lymuri2wbc26https://bsky.app/profile/yasudaigaku.bsky.social/post/3lbwge6u22k2iThanks to Gideon @costerlab.bsky.social for visiting JFCR and for a very inspiring seminar. We learned a lot about the impact of many DNA structures on genome replication/stability!27 Nov 2024 11:15 +0000at://did:plc:knpfv4wvthbfsog5cebfifig/app.bsky.feed.post/3lbwge6u22k2i