Physician scientist at Charité Berlin, interest in TB genomic epidemiology, host pathogen diversity, and clinical AIhttps://bsky.app/profile/mattgroeschel.bsky.socialhttps://bsky.app/profile/mattgroeschel.bsky.social/post/3llxydqvwpc2scongrats Peter and team [contains quote post or other embedded content]04 Apr 2025 08:21 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3llxydqvwpc2shttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lkfzz6byhk25Love it! Time to move beyond SNP clustering = transmission. Although important to not forget host infectiousness, exposure time and contact susceptibility in the equation next to pathogen genomes [contains quote post or other embedded content]15 Mar 2025 11:38 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lkfzz6byhk25https://bsky.app/profile/mattgroeschel.bsky.social/post/3lialifbowk2f‚Gaps in TB funding could lead to increased transmission globally.‘ Rapid communication from StopTB on the impact of foreign aid freeze. [contains quote post or other embedded content]15 Feb 2025 20:44 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lialifbowk2fhttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lgbf4w5qic2lImportant lessons from South Africa on screening contacts of active TB: ‚more than 80% of confirmed TB cases among HHC were asymptomatic. CXR screening missed more than 40% of these asymptomatic cases‘ [contains quote post or other embedded content]21 Jan 2025 17:33 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lgbf4w5qic2lhttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lfn3wniyfk2hGreat that your book will be available in German. [contains quote post or other embedded content]13 Jan 2025 15:55 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lfn3wniyfk2hhttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lcgessiyq22pInteresting study showing several host RNA signatures poorly generalized to a new cohort predicting sputum conversion at 8 weeks. [contains quote post or other embedded content]03 Dec 2024 19:30 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lcgessiyq22phttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lbyrwyk26k2pCongrats @jasonandrews.bsky.social et al. Enjoyed reading this study demonstrating the use of low frequency variants in household pairs / transmission with most variation found in PE/PPE genes. Could be a great addition to breathe, phybreak, transphylo [contains quote post or other embedded content]28 Nov 2024 09:47 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lbyrwyk26k2phttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lbpxe57psk2jthis will be a great read over winter break. [contains quote post or other embedded content]24 Nov 2024 21:30 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lbpxe57psk2jhttps://bsky.app/profile/mattgroeschel.bsky.social/post/3lb252z6f6c2jAlvaro Schwalb presenting latest modeling results of TB infection burden at the Union: they estimate that 2% of global population was recently (<2 years) infected with viable Mtb, that’s 156M people. Their preprint is here: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=501794316 Nov 2024 05:14 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3lb252z6f6c2jhttps://bsky.app/profile/mattgroeschel.bsky.social/post/3laqzzr6ivs2nSo happy the TB community here seems to get some serious momentum so we can all delete our X accounts12 Nov 2024 14:26 +0000at://did:plc:kvv5vnbvt6xfa77kshixd7nu/app.bsky.feed.post/3laqzzr6ivs2n