Swiss National Center of Competence in Research (NCCR): The role of RNA in disease mechanisms. Propelling research forward since 2014. @snsf-ch.bsky.social @unibern.bsky.social @ethzurich.bsky.social https://nccr-rna-and-disease.ch/https://bsky.app/profile/nccr-rna-disease.bsky.socialhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mkpnibjqis2zA tiny chemical tweak changed medicine! 💉 Discover how RNA modifications made efficient mRNA vaccines against Covid-19 possible, for which the 2023 Nobel Prize in Physiology or Medicine was awarded. https://www.youtube.com/watch?v=1SQdNpQ5B08 @snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social30 Apr 2026 12:47 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mkpnibjqis2zhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mknwii6pbc2zFor gene expression,there exist "dimmer switches"!Discover how microRNAs fine-tune protein production in health&disease.For their discovery,the 2024 Nobel Prize in Physiology or Medicine was awarded. https://www.youtube.com/watch?v=qoUoH0VXp6M @snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social29 Apr 2026 20:22 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mknwii6pbc2zhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mkkpt3prr22jWhy do we age? 🧬 Meet telomerase, the molecular machine that rebuilds chromosome ends and its roles in health & disease. For its discovery, the 2009 Nobel Prize in Physiology or Medicine was awarded. https://www.youtube.com/watch?v=dXLEV6-_2Os @snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social28 Apr 2026 13:45 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mkkpt3prr22jhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mkinfvjyns2mReprogramming cells with precision! 🎯 Learn how RNA interference (RNAi) silences specific genes to treat diseases. For its discovery, the 2006 Nobel Prize in Physiology or Medicine was awarded. https://www.youtube.com/watch?v=rZY1sEv1JN4 @snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social27 Apr 2026 17:57 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mkinfvjyns2mhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mk6dcskbfc27Our genes come in bits & pieces!🧬Learn how splicing "cuts & pastes" RNA to create different proteins from a single gene, for its discovery the 1993 Nobel Prize in Physiology or Medicine was awarded. https://www.youtube.com/watch?v=-x7Heb3wh6Q @snsf.ch @unibe.ch @ethz.ch @nobelprize.org @rnasociety.bsky.social23 Apr 2026 15:29 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mk6dcskbfc27https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mk2wfxe26l23Preprint by the Leidel, Thiel & Pillai labs with co-1st authors R. Pandey & N. Ebert "Loss of host factor-mediated m6Am methylation of the viral RNA cap impairs SARS CoV-2 replication" @biorxivpreprint.bsky.social https://doi.org/10.64898/2026.04.10.717462 @profvolkerthiel.bsky.social @mcm5s2u.bsky.social @unibe.ch22 Apr 2026 07:00 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mk2wfxe26l23https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mjzqmxeuhs23Imagine curing diseases by rewriting the code of life!🧬Discover how CRISPR/Cas9, guided by RNA, acts as molecular scissors to precisely edit genomes, for which the 2020 Nobel Prize in Chemistry was awarded https://www.youtube.com/watch?v=0rz-ZZYvz3g @snsf.ch @unibe.ch @ethz.ch @nobelprize.org21 Apr 2026 19:44 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mjzqmxeuhs23https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mjmjc77wx22wDNA holds the blueprints, but how are proteins built?Meet the ribosome, a nanomachine.For the studies of it,the 2009 Chemistry Nobel Prize was awarded. Watch the video on YouTube with subtitles in English, French & German: https://www.youtube.com/watch?v=2txJsS_l4zo @snsf.ch @unibe.ch @ethz.ch @nobelprize.org16 Apr 2026 13:28 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mjmjc77wx22whttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mjh5p6ysk224Preprint by the Polacek lab and collaborators with first author EunBin Kong "Stress-induced vtRNA1-1 modulates redox homeostasis and ferroptosis susceptibility in hepatocellular carcinoma cells" @biorxivpreprint.bsky.social https://doi.org/10.64898/2026.03.30.715395 @unibe.ch14 Apr 2026 10:18 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mjh5p6ysk224https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mjf5x5q3422kHow did life begin?🧬Before DNA & proteins, RNA paved the way for modern life. Learn about "ribozymes". The discoverers of catalytic RNAs were awarded the 1989 Nobel Prize in Chemistry! Watch the video with subtitles in DE, EN & FR: https://www.youtube.com/watch?v=LjtNGhBHNkw @snsf.ch @unibe.ch @ethz.ch13 Apr 2026 15:17 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mjf5x5q3422khttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mj5iedofz22pRNA Explained Video Series: From CRISPR to Vaccines - 8 RNA Discoveries That Revolutionized Biology!🎬Explore 8 Nobel Prize-winning breakthroughs. They are the final public outreach activity of the NCCR RNA & Disease. Join us on this journey into RNA science! Coming soon! @snsf.ch @ethz.ch @unibe.ch10 Apr 2026 14:02 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mj5iedofz22phttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3miin5k4jav2nPaper by the Allain and Jeschke labs with first author Cristina Nguyen "Characterization of flexible RNA binding by tandem RNA recognition motifs through integrative ensemble modelling" in Nucleic Acids Research ( @narjournal.bsky.social) https://nccr-rna-and-disease.ch/news/articles/choreography-of-tandem-rrms-on-rna @ethz.ch #NMR02 Apr 2026 07:02 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3miin5k4jav2nhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mib3p2m4ns23Review by the Mühlemann Lab with first author Wojciech Teodorowicz "Molecular determinants and therapeutic targeting of stop codon readthrough in eukaryotic translation" @jmolbiol.bsky.social https://nccr-rna-and-disease.ch/news/articles/review-on-stop-codon-readthrough-and-therapeutically-targeting-it @omuhlemann-lab.bsky.social @unibe.ch30 Mar 2026 07:01 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mib3p2m4ns23https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mhznnqi3ui26Publication by the Corn lab and collaborators with first author Lena Kobel " DisTAL-Seq: A TALEN-specific adaptation of DISCOVER-Seq for off-target profiling" in Molecular Therapy Nucleic Acids: https://nccr-rna-and-disease.ch/news/articles/detecting-talen-off-targets @jcornlab.bsky.social @moltherapy.bsky.social @ethz.ch27 Mar 2026 08:01 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mhznnqi3ui26https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mhifrafuns2d🔬 We are pleased to welcome Kamena Kostova (Stowers Institute for Medical Research, USA) as the next speaker in our NCCR RNA & Disease Seminar Series! 🗓️ 23.03.2026 – 16:30 📍 University of Bern, DCBP 🗓️ 24.03.2026 – 11:00 📍ETH Zurich, Hönggerberg For more Info: lnkd.in/ei92r5gg @unibe.ch @ethz.ch20 Mar 2026 11:24 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mhifrafuns2dhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mhaiyevlxf2kPublication by the Gatfield and Jonas labs with co-first authors Enes Arpa and Michael Taschner "Active Site Assembly by SMG5 as a Mechanism for SMG6 Endonuclease Licencing in Nonsense-mediated mRNA Decay" @jmolbiol.bsky.social https://nccr-rna-and-disease.ch/news/articles/nmd-pins-twice-for-mrna-degradation @unil.bsky.social @ethz.ch17 Mar 2026 08:01 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mhaiyevlxf2khttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mgrg7f37vu22We would like to congratulate Sebastian Leidel ( @mcm5s2u.bsky.social ) on receiving the 2026 RNA Society Mid-Career Award! https://nccr-rna-and-disease.ch/news/articles/sebastian-leidel-rna-society-mid-career-award @rnasociety.bsky.social @unibe.ch @snsf.ch11 Mar 2026 08:01 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mgrg7f37vu22https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mfthcqectq22🔬 Next in the NCCR RNA & Disease Seminar Series: Prof. Danny Nedialkova (Max Planck Institute of Biochemistry, Germany)! 🗓️ 02.03.2026: 16:30 – University of Bern, DCBP 🗓️ 03.03.2026: 16:00 – ETH Zurich, Hönggerberg More info: buff.ly/7Lkx00l... @unibe.ch @ethz.ch @snf-fns.ch27 Feb 2026 10:01 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mfthcqectq22https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3mfbx6xh6vk2g🗓️ We are pleased to announce the NCCR RNA & Disease Seminar Series for the Spring Semester 2025/2026. For more information, visit: lnkd.in/ei92r5gg @unibe.ch @ethz.ch @snf-fns.ch20 Feb 2026 10:57 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3mfbx6xh6vk2ghttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m7rpcixtfc2nCongratulations! [contains quote post or other embedded content]12 Dec 2025 08:47 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m7rpcixtfc2nhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m7as7iqk322gThis weekend, the 37th edition of the Telethon takes place on December 6 & 7, which raises donations for supporting families with children with rare genetic diseases and research on these diseases: telethon.ch/de/ https://telethon.ch/de/05 Dec 2025 15:24 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m7as7iqk322ghttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m6z2vgbrg22vCongratulations to Raphael Morscher (Associate Member) on becoming an EMBO Young Investigator! [contains quote post or other embedded content]02 Dec 2025 13:38 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m6z2vgbrg22vhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m6yp3exswk23Six days left to submit abstracts, also for talks, and register for the Swiss RNA Workshop 2026! The deadline has been extended to December 8, 2026. swissrnaws.dcbp.unibe.ch https://swissrnaws.dcbp.unibe.ch/02 Dec 2025 10:07 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m6yp3exswk23https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m5xryuyjgc26Preprint by the lab of Jacob Corn & collaborators with first author Moritz Schlapansky "Cell-stereotyped DNA repair outcomes are widespread during genome editing" @biorxivpreprint.bsky.social https://doi.org/10.1101/2025.10.23.684114 @jcornlab.bsky.social @ethz.ch19 Nov 2025 08:01 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m5xryuyjgc26https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m5vfrortf22rPublication by the Kutay lab with first author Claudia Gafko "Establishment of an imaging-based screening pipeline for the identification of human ribosome biogenesis inhibitors" in BMC Biol https://nccr-rna-and-disease.ch/news/articles/screening-pipeling-for-ribosome-biogenesis-inhibition @kutaylab.bsky.social @ethz.ch18 Nov 2025 09:17 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m5vfrortf22rhttps://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m5sqzr2fip24Paper by the Sander & Lee labs & collaborators with co-1st authors Gregory Phelps & Sinem Kurt "Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus" @natmicrobiol.nature.com https://nccr-rna-and-disease.ch/news/articles/harnessing-a-mycobacterial-resitance-machinery-to-combat-an-antibiotic-nightmare17 Nov 2025 08:00 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m5sqzr2fip24https://bsky.app/profile/nccr-rna-disease.bsky.social/post/3m5lrxeup5c2jPublication by the Allain lab with co-first authors Johannes Schmoll and Mihajlo Novakovic (also co-corresponding) "Water-detected NMR allows dynamic observations of repeat-expansion RNA condensates" in Nature Chemistry https://nccr-rna-and-disease.ch/news/articles/water-detected-nmr-allows-dynamic-observations-of-repeat-expansion-rna-condensates @ethz.ch @natchem.nature.com #NMRchat14 Nov 2025 13:28 +0000at://did:plc:lapcde26bywpmfatb72iggod/app.bsky.feed.post/3m5lrxeup5c2j