PI at EPFL / gene regulation / chromatin / epigenetics / genomics / stem cells / transcription factors / single molecule / protein turnover https://www.epfl.ch/labs/suter-lab/ - and 🎹 https://www.youtube.com/@davidsuter594 / https://soundcloud.com/suterd7https://bsky.app/profile/davidsuter.bsky.socialhttps://bsky.app/profile/davidsuter.bsky.social/post/3mujgcc2clk2zSounds very exciting - for sure my own ignorance, but I cannot help being surprised that in some fields, N=1 --> big splash. In mine, N=1 --> ...most likely an artifact. [contains quote post or other embedded content]02 Sep 2026 07:34 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mujgcc2clk2zhttps://bsky.app/profile/davidsuter.bsky.social/post/3mpbnts5yb22pVery much enjoyed this preprint - getting closer to a quantitative understanding on how promoter/enhancer interactions drive transcriptional activity: https://www.biorxiv.org/content/10.64898/2026.06.25.734173v1.full.pdf27 Jun 2026 14:22 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mpbnts5yb22phttps://bsky.app/profile/davidsuter.bsky.social/post/3moxnlikbpk2wWhat a tour-de-force ! Makes me think that the mechanisms enhancer-mediated transcriptional activation are now truly falling into place [contains quote post or other embedded content]23 Jun 2026 14:50 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3moxnlikbpk2whttps://bsky.app/profile/davidsuter.bsky.social/post/3morwixe5uc2vQ.E.D. 🤦‍♀️🇨🇭🤦‍♂️21 Jun 2026 08:14 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3morwixe5uc2vhttps://bsky.app/profile/davidsuter.bsky.social/post/3mofgm2cgr22dNon-science post: join us in beautiful Cully for the Lavaux Festival www.lavauxclassic.ch ! I will play along with many other laureates of the Lavaux piano competition - concert will take place outside on the lake shore, free entrance, three hours of music, Saturday June 20, 13:00 to 16:00 🎹 🎶16 Jun 2026 08:58 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mofgm2cgr22dhttps://bsky.app/profile/davidsuter.bsky.social/post/3mnh4hqvroc27Not only at MIT... [contains quote post or other embedded content]04 Jun 2026 07:36 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mnh4hqvroc27https://bsky.app/profile/davidsuter.bsky.social/post/3mld7a34zec2s📢 New preprint alert ! https://www.biorxiv.org/content/10.64898/2026.05.06.723176v1 Joanna Dembska developed a highly scalable image-base screening platform for protein turnover modulators in human neurons, based on our fluorescent timer system. Protein turnover is perturbed in nearly all neurodegenerative diseases ...08 May 2026 07:25 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mld7a34zec2shttps://bsky.app/profile/davidsuter.bsky.social/post/3mks6xwj7lk2lThis thread is brilliant [contains quote post or other embedded content]01 May 2026 13:05 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mks6xwj7lk2lhttps://bsky.app/profile/davidsuter.bsky.social/post/3mkaftdtfcc2bVery nice work on histone modifications of mitotic chromosomes ! And also points at issues working with nocodazole-mediated synchronization, which still so many labs use - this work here shows how it artificially results in loss of mitotic histone acetylation. https://www.cell.com/molecular-cell/pdf/S1097-2765(26)00234-0.pdf24 Apr 2026 11:20 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mkaftdtfcc2bhttps://bsky.app/profile/davidsuter.bsky.social/post/3mib35imuec2pNon-science post - Any plans for Easter ? If not, come join us in Evian 🇫🇷 on 4.4. for the piano marathon ! My menu: Brahms : Rhapsodie op.79 n°1, Schumann : 2 pieces from Fantaisiestücke op. 12, Chopin : Ballade n°4 & Mazurka op.59 n°2 info 👇 marathondupiano.com https://www.youtube.com/watch?v=ya7ManYMYGU&list=RDya7ManYMYGU&start_radio=130 Mar 2026 06:51 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mib35imuec2phttps://bsky.app/profile/davidsuter.bsky.social/post/3mhx5pr7gqk2dEmail spam in 2026 is so out of control that it feels like smashing nagging mosquitoes on a hot summer night26 Mar 2026 08:10 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mhx5pr7gqk2dhttps://bsky.app/profile/davidsuter.bsky.social/post/3mhneilqd622dDemons - Dostoïevski [contains quote post or other embedded content]22 Mar 2026 10:45 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mhneilqd622dhttps://bsky.app/profile/davidsuter.bsky.social/post/3mhi6ky3kkc2nVery interesting work from on the role of IDRs in DNA binding specificity - in the cases studied here, the DBD plays almost no role 😮. https://www.science.org/doi/epdf/10.1126/science.aeb6487 https://www.science.org/doi/epdf/10.1126/science.aeb6487I20 Mar 2026 09:15 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mhi6ky3kkc2nhttps://bsky.app/profile/davidsuter.bsky.social/post/3mhcy7if6vk2rHow do electrostatic forces impact TF search ? In joint effort with @beatfierz.bsky.social , tour-de-force from @simsakong.bsky.social who single-handedly combined in vitro SPT on DNA & chromatin, in cellulo SPT, ChIP-seq and ATAC-seq https://www.nature.com/articles/s41467-026-69284-518 Mar 2026 07:38 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mhcy7if6vk2rhttps://bsky.app/profile/davidsuter.bsky.social/post/3mh5wjq6cqk2mWaou ! Fabulous documentary, so much deserved ! [contains quote post or other embedded content]16 Mar 2026 07:25 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mh5wjq6cqk2mhttps://bsky.app/profile/davidsuter.bsky.social/post/3mguglmdav22mSubmitting to Nature Friend instead of Nature [contains quote post or other embedded content]12 Mar 2026 12:46 +0000at://did:plc:laxirmcgirkushodsbgjswwd/app.bsky.feed.post/3mguglmdav22m