Scientist studying how mechanical force affects biology / Tinkerer / Professor / Engineerhttps://bsky.app/profile/jie-xu.bsky.socialhttps://bsky.app/profile/jie-xu.bsky.social/post/3lumvgn7pqc2yThanks Ishan and Vishva for commenting on our work regarding NINJ1's role of weakening the plasma membrane for rupture under mechanical stress. We feel blessed and grateful for the support of fellow scientists in the community. [contains quote post or other embedded content]23 Jul 2025 11:17 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lumvgn7pqc2yhttps://bsky.app/profile/jie-xu.bsky.social/post/3lubyovhees2sLove Loren's home brew! His passion is unparalleled. He coauthored a paper in the prestigious journal Cell on domestication and divergence of yeast, a very interesting read! https://www.cell.com/fulltext/S0092-8674(16)31071-6 [contains quote post or other embedded content]19 Jul 2025 03:16 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lubyovhees2shttps://bsky.app/profile/jie-xu.bsky.social/post/3lu4ombwzsk25Excited to reunite with former benchmates at International Ion Channel Conference. Apologize for the severely jet lagged faces, but at least we remembered the golden rule of @ardemp.bskyverified.social lab regarding conferences: “No badges outside the venues”. We think Ardem will be proud.17 Jul 2025 00:32 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lu4ombwzsk25https://bsky.app/profile/jie-xu.bsky.social/post/3lr6ohil4oc2gExcited to share our latest story in Nature. We developed a high-throughput cellular stretch system to look for genes regulating membrane rupture under tension, and found an amazing small protein called NINJ1 that weakens the membrane for rupture! H/T to Zozo, my 10-y.o. for her artist's impression😃09 Jun 2025 15:19 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lr6ohil4oc2ghttps://bsky.app/profile/jie-xu.bsky.social/post/3lohobgdr3k2mAs a researcher working on mechanotransduction, celebration of May the 4th is obligatory. [contains quote post or other embedded content]06 May 2025 00:54 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lohobgdr3k2mhttps://bsky.app/profile/jie-xu.bsky.social/post/3lcqxyktlbs2qWoke up to the whirling sound of helicopters, went to the balcony to see what’s going on and was treated with amazing skyline view, the calm pearl river and ongoing Guangzhou marathon. A crisp morning like this is hard to come by.08 Dec 2024 00:40 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lcqxyktlbs2qhttps://bsky.app/profile/jie-xu.bsky.social/post/3lcn4rmxw6c2iNow that’s some serious thrust… [contains quote post or other embedded content]06 Dec 2024 11:54 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3lcn4rmxw6c2ihttps://bsky.app/profile/jie-xu.bsky.social/post/3laxzwzdzrm23I had the privilege to witness this groundbreaking discovery six months after I joined the Patapoutian lab. I remember asking Bertrand "What is it?" and he replied "FAM38A". I knew it was a big deal at the time, but little did I know that this would become one of biggest discoveries in biology. [contains quote post or other embedded content]15 Nov 2024 09:13 +0000at://did:plc:ln2ra5ngdebabjoh6phvhtbc/app.bsky.feed.post/3laxzwzdzrm23