Professor of Medicinal Chemistry at Newcastle University and Cancer Research Horizons, Director of MoSMed CDT and Editor-in-Chief of RSC Medicinal Chemistryhttps://bsky.app/profile/mikewaring.bsky.socialhttps://bsky.app/profile/mikewaring.bsky.social/post/3manqwvon7226New paper out in J Med Chem showing that covalent targeting of C775 has the potential to treat osimertinib resistant lung cancer. Really proud of this work and the team that did it! @nudrugdiscovery.bsky.social @nucancer.bsky.social @crhorizons.bsky.social https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c0292423 Dec 2025 12:31 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3manqwvon7226https://bsky.app/profile/mikewaring.bsky.social/post/3lrihgtxiec2kNew paper: We've always used TPGS in our micellar #DEL synthesis. This paper shows you can find better ones using @baonguyengroup.bsky.social surfactant map. Great work from Jake Odger et al https://pubs.rsc.org/en/Content/ArticleLanding/2025/OB/D5OB00864F13 Jun 2025 12:40 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lrihgtxiec2khttps://bsky.app/profile/mikewaring.bsky.social/post/3lr6emcsjjk2bSomething makes me think that this invite might have been autogenerated...09 Jun 2025 12:23 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lr6emcsjjk2bhttps://bsky.app/profile/mikewaring.bsky.social/post/3lmtqo6kyys2hStarting the @mosmedcdt.bsky.social conference. It will get better from here! [contains quote post or other embedded content]15 Apr 2025 09:18 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lmtqo6kyys2hhttps://bsky.app/profile/mikewaring.bsky.social/post/3lmkm7kzxos2hGroup trip to the pub / watch the bins being emptied.11 Apr 2025 18:05 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lmkm7kzxos2hhttps://bsky.app/profile/mikewaring.bsky.social/post/3lmiemugjl225New paper published today describing some SAR on EGFR inhibitors including an interesting effect of a pair of enantiomers on covalent biinding https://www.nature.com/articles/s42004-025-01501-6?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20250410&utm_content=10.1038/s42004-025-01501-610 Apr 2025 20:44 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lmiemugjl225https://bsky.app/profile/mikewaring.bsky.social/post/3lkdkxzv37k27Highlighting scientists and the possibility that they may also be humans, give them a follow https://bsky.app/profile/facesofscience.bsky.social14 Mar 2025 12:04 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lkdkxzv37k27https://bsky.app/profile/mikewaring.bsky.social/post/3ljzvndewa22xWe have a PhD studentship in the @nudrugdiscovery.bsky.social @chemistryncl.bsky.social with me and @hannahstewart92.bsky.social to develop methods of making macrocycles as a new class of antimicrobial agents. Apply at the link and contact us if you have questions. https://www.findaphd.com/phds/project/a-build-couple-transform-approach-to-diverse-macrocyclic-libraries-for-antimicrobial-drug-discovery/?p18274510 Mar 2025 15:48 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3ljzvndewa22xhttps://bsky.app/profile/mikewaring.bsky.social/post/3ljohvrrqh227Check out RSC Medicinal Chemistry now on Bluesky @rscmedchem.rsc.org https://bsky.app/profile/rscmedchem.rsc.org06 Mar 2025 02:43 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3ljohvrrqh227https://bsky.app/profile/mikewaring.bsky.social/post/3lirdqilubk2rYesterday Julian Knight officially retired from @chemistryncl.bsky.social Julian is a brilliant organic chemistry lecturer and will be sorely missed22 Feb 2025 12:41 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lirdqilubk2rhttps://bsky.app/profile/mikewaring.bsky.social/post/3lhnzszidh22tCongratulations to Dr Matt Anderson on passing his PhD viva yesterday. @chemistryncl.bsky.social @nudrugdiscovery.bsky.social08 Feb 2025 11:40 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lhnzszidh22thttps://bsky.app/profile/mikewaring.bsky.social/post/3lh2mar7n7k2jWe have a #PhDstudentship starting in Sept with me and @hannahstewart92.bsky.social ideal for candidates with interest in research in #medicinalchemistry and #organicsynthesis Contact us for more details but apply through the university portal, details in the link: https://www.ncl.ac.uk/postgraduate/fees-funding/search-funding/?code=DLA251731 Jan 2025 18:17 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lh2mar7n7k2jhttps://bsky.app/profile/mikewaring.bsky.social/post/3lc46tuivtk2fLooking forward to speaking at the #scireviewmeeting next week. Some interesting topics... https://www.soci.org/events/young-chemists-panel/2024/30th-sci-annual-review-meeting--new-directions-in-organic-chemistry29 Nov 2024 18:16 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lc46tuivtk2fhttps://bsky.app/profile/mikewaring.bsky.social/post/3lbp3fj2qec2vNewcastle Drug Discovery Group arrives on Bluesky https://bsky.app/profile/nudrugdiscovery.bsky.social24 Nov 2024 13:10 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lbp3fj2qec2vhttps://bsky.app/profile/mikewaring.bsky.social/post/3lbmokqzgzs2hLooking forward to speaking at this on Tuesday. Apparently they are keen to hear about #fraglites and #dels - we will see https://www.nepic.co.uk/event/nepic-pharma-connect-3/23 Nov 2024 14:15 +0000at://did:plc:lpxcfdlmvb6wfp7zjdsinvbd/app.bsky.feed.post/3lbmokqzgzs2h