Genetics of cardiovascular diseases Post-Doc @cam.ac.uk @dphpc.bsky.social https://www.inouyelab.org/home/people 🇬🇧 PhD @ulaval.ca @IUCPQ 🇨🇦 MSc @upcite.bsky.social @lvts 🇫🇷 From 🇫🇷/🇱🇰https://bsky.app/profile/hasanga.bsky.socialhttps://bsky.app/profile/hasanga.bsky.social/post/3lsy2tnubpk2d📣 Clap de fin for my PhD work 🎬! The fourth and final article is now available in @commsmed.nature.com. We benchmarked a set of PGS for cardiovascular traits available from the pgscatalog.org resource in different Canadian cohorts🍁. See more 👇🏽 - Link (OA): https://www.nature.com/articles/s43856-025-00981-w (1/4)02 Jul 2025 11:02 +0000at://did:plc:lw2ro2gdvdv2dpemsr5ob44h/app.bsky.feed.post/3lsy2tnubpk2dhttps://bsky.app/profile/hasanga.bsky.social/post/3lmu4xaepvk2j📣 Feeling extremely lucky to have modestly contributed to this masterpiece, investigating the impact of loss-of-function mutations in APOC3 gene on aortic valve disease risk reduction. See more in JACC 👇🏽 https://www.jacc.org/doi/10.1016/j.jacc.2025.02.02815 Apr 2025 12:58 +0000at://did:plc:lw2ro2gdvdv2dpemsr5ob44h/app.bsky.feed.post/3lmu4xaepvk2jhttps://bsky.app/profile/hasanga.bsky.social/post/3lmhbwdc4bk2y📣 Thrilled to share this paper. We leveraged transcriptomic data from one of the largest existing aortic valve collection. We identified genes/pathways involved in disease progression/severity, with distinct transcriptomic signatures in TAV vs BAV. Perspectives for potential therapeutics? See more👇🏽 https://www.sciencedirect.com/science/article/pii/S2452302X2500028210 Apr 2025 10:23 +0000at://did:plc:lw2ro2gdvdv2dpemsr5ob44h/app.bsky.feed.post/3lmhbwdc4bk2yhttps://bsky.app/profile/hasanga.bsky.social/post/3lmfzcammjs2dCan testify to this -> awesome research environment, with access to great ressources, sharing space and time with incredible colleagues and renowned experts... [contains quote post or other embedded content]09 Apr 2025 22:16 +0000at://did:plc:lw2ro2gdvdv2dpemsr5ob44h/app.bsky.feed.post/3lmfzcammjs2dhttps://bsky.app/profile/hasanga.bsky.social/post/3lkbdy6ym4s22📣 More data on the impact of high Lp(a) levels on Aortic Valve Disease/CAVS! Patients are more likely to undergo AV replacement during their life course, and face a higher risk of combined CV events. Link (Open Access)👇🏽: https://www.ahajournals.org/doi/10.1161/JAHA.124.03895513 Mar 2025 14:53 +0000at://did:plc:lw2ro2gdvdv2dpemsr5ob44h/app.bsky.feed.post/3lkbdy6ym4s22