Structural Molecular Biology | Cell Adhesion and Signaling Also @peredalab@mstdn.science https://bsky.app/profile/peredalab.bsky.socialhttps://bsky.app/profile/peredalab.bsky.social/post/3mvrt6xaxoc2pThanks a lot to @instruct-eric.bsky.social this Scientific Highlight portraying our recent work on the structural basis of the interaction of an anti-HPA-1a alloantibody with integrin αIIbβ3 https://instruct-eric.org/scientifichighlights/international-cryo-electron-microscopy-collaboration-helps-to-improve-understanding-of-fetalneonatal18 Sep 2026 09:11 +0000at://did:plc:muvp2ee6kdj5dfeaw54yqnb5/app.bsky.feed.post/3mvrt6xaxoc2phttps://bsky.app/profile/peredalab.bsky.social/post/3mrpnwf4yj22tHappy to share our latest paper! https://www.science.org/doi/10.1126/sciadv.aed9833 We visualized by cryo-EM how a disease-causing anti-HPA-1a antibody binds to integrin αIIbβ3 and locks it in an inactive state Great colab with Coert Margadant’s lab & groups at Osaka Univ, Sanquin, CNB-CSIC, ISBG Details below… 1/928 Jul 2026 14:51 +0000at://did:plc:muvp2ee6kdj5dfeaw54yqnb5/app.bsky.feed.post/3mrpnwf4yj22t