Manually curated posts on type III secretion system. A project managed by @e_sotog now at @ccg_unam https://www.ccg.unam.mx/en/jose-eduardo-soto-guzman/https://bsky.app/profile/t3sss.bsky.socialhttps://bsky.app/profile/t3sss.bsky.social/post/3mkdc3dfxe22aXopA: a novel type III secretion system effector in Xenorhabdus that modulates host cell responses through apoptosis, autophagy, and immune evasion | Microbiology Spectrum https://journals.asm.org/doi/10.1128/spectrum.03871-2525 Apr 2026 14:51 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mkdc3dfxe22ahttps://bsky.app/profile/t3sss.bsky.social/post/3mkbjssvfus2oGenomic characterization of antimicrobial resistance and virulence determinants in Salmonella Infantis isolated from human, food, and animal sources | Applied and Environmental Microbiology https://journals.asm.org/doi/10.1128/aem.01975-2524 Apr 2026 22:04 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mkbjssvfus2ohttps://bsky.app/profile/t3sss.bsky.social/post/3mkbjo5xbbk2uComprehensive characterization of virulence factors in Pseudomonas aeruginosa clinical isolates from Bushehr, Iran: High proportion of exoU-positive isolates https://link.springer.com/article/10.1186/s12866-026-04925-924 Apr 2026 22:01 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mkbjo5xbbk2uhttps://bsky.app/profile/t3sss.bsky.social/post/3mkbjndpo3k2uA bacterial family of fatty acid acyltransferases related to the Shigella effector IcsB | mBio https://journals.asm.org/doi/10.1128/mbio.03890-2524 Apr 2026 22:01 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mkbjndpo3k2uhttps://bsky.app/profile/t3sss.bsky.social/post/3mk7mvniinc2a SPI2 T3SS effectors facilitate enterocyte apical to basolateral transmigration of Salmonella-containing vacuoles in vivo https://www.tandfonline.com/doi/full/10.1080/19490976.2021.1973836#abstract24 Apr 2026 03:54 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mk7mvniinc2ahttps://bsky.app/profile/t3sss.bsky.social/post/3mk2arx3ffk2gPhosphorylation of rhizobial effector NopZ by soybean NORK promotes association with NENA and enhances nodulation https://www.nature.com/articles/s41467-026-72277-z22 Apr 2026 00:33 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mk2arx3ffk2ghttps://bsky.app/profile/t3sss.bsky.social/post/3mjxrmoh4tc2qT3SS effector and regulator discovery by predicting interacting partners of T3SS chaperones in Pseudomonas aeruginosa - Zhang - 2026 - Protein Science - Wiley Online Library https://onlinelibrary.wiley.com/doi/full/10.1002/pro.7055121 Apr 2026 00:57 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mjxrmoh4tc2qhttps://bsky.app/profile/t3sss.bsky.social/post/3mjnlhn2hvs2cEnteropathogenic E. coli-mediated Fast and Coordinated Ca2+ responses regulate NF-κB activation https://www.biorxiv.org/content/10.1101/2025.08.06.668902v216 Apr 2026 23:40 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mjnlhn2hvs2chttps://bsky.app/profile/t3sss.bsky.social/post/3mjnle3liis2cGlobal transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa https://doi.org/10.7554/eLife.103346.416 Apr 2026 23:38 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mjnle3liis2chttps://bsky.app/profile/t3sss.bsky.social/post/3mjbj4wrex22zRegulator-derived growth and fitness costs of Salmonella SPI-2 expression are environment specific and T3SS independent https://www.biorxiv.org/content/10.64898/2026.04.10.717833v112 Apr 2026 04:26 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mjbj4wrex22zhttps://bsky.app/profile/t3sss.bsky.social/post/3mjbibtgmm22mIn @eLife.bsky.social: Gene synteny and translational coupling of sctS and sctT facilitate assembly of the unique helical T3SS export apparatus in Salmonella Typhimurium https://doi.org/10.7554/eLife.110767.112 Apr 2026 04:11 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mjbibtgmm22mhttps://bsky.app/profile/t3sss.bsky.social/post/3mj6bf3ntzc2qIn @eLife.bsky.social: Gene synteny and translational coupling of sctS and sctT facilitate assembly of the unique helical T3SS export apparatus in Salmonella Typhimurium https://doi.org/10.7554/eLife.110767.110 Apr 2026 21:30 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mj6bf3ntzc2qhttps://bsky.app/profile/t3sss.bsky.social/post/3mizqtahlf22pEnterohemorrhagic Escherichia coli senses colonic oxygen availability to modulate its virulence and colonization: iScience https://www.cell.com/iscience/fulltext/S2589-0042%2826%2901007-209 Apr 2026 02:23 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mizqtahlf22phttps://bsky.app/profile/t3sss.bsky.social/post/3mizbgi2tk22hThe MarR Family Transcriptional Regulator EmrR Negatively Regulates the Type III Secretion System (T3SS) and Positively Modulates Pathogenicity in Dickeya oryzae - Lv - 2026 - Molecular Plant Pathology - Wiley Online Library https://bsppjournals.onlinelibrary.wiley.com/doi/10.1111/mpp.7025508 Apr 2026 21:47 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mizbgi2tk22hhttps://bsky.app/profile/t3sss.bsky.social/post/3mizbg5bdus2aClass II chaperones: indispensable components of the Gram-negative bacterial T3SS as guardians of translocators https://link.springer.com/article/10.1007/s00203-026-04878-708 Apr 2026 21:47 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mizbg5bdus2ahttps://bsky.app/profile/t3sss.bsky.social/post/3mizbf46urs2mFull article: High-throughput transposon sequencing identifies HprR as a key regulator of the LEE operon and virulence in E. coli O157:H7 https://www.tandfonline.com/doi/full/10.1080/21505594.2026.265385508 Apr 2026 21:46 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mizbf46urs2mhttps://bsky.app/profile/t3sss.bsky.social/post/3mizbf2fcyc2aPathogen hijacks focal adhesion signaling by a T3SS effector CteX | PNAS https://www.pnas.org/doi/10.1073/pnas.2530673123?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed08 Apr 2026 21:46 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mizbf2fcyc2ahttps://bsky.app/profile/t3sss.bsky.social/post/3mhwduzc5d225Fis suppresses late-stage virulence gene expression in Yersinia pseudotuberculosis at environmental temperatures https://dx.plos.org/10.1371/journal.ppat.101410526 Mar 2026 00:28 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mhwduzc5d225https://bsky.app/profile/t3sss.bsky.social/post/3mhihapvzcs2eSimultaneous inhibition of bacterial virulence and anti-phage defense systems by synergistic bacteriophage counter-defense proteins https://link.springer.com/article/10.1038/s44318-026-00740-020 Mar 2026 11:51 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mhihapvzcs2ehttps://bsky.app/profile/t3sss.bsky.social/post/3mhhdcmfz522sCatabolism of serine enantiomers represses enterohemorrhagic Escherichia coli virulence factors via modulation of the nitrogen stress response | PNAS https://www.pnas.org/doi/full/10.1073/pnas.253291612320 Mar 2026 01:08 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mhhdcmfz522shttps://bsky.app/profile/t3sss.bsky.social/post/3mhhdc5wj422hHost adaptation in Salmonella enterica serovar Typhimurium: population structure, pathovariants, and genomic mechanisms | Applied and Environmental Microbiology https://journals.asm.org/doi/10.1128/aem.02201-2520 Mar 2026 01:07 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mhhdc5wj422hhttps://bsky.app/profile/t3sss.bsky.social/post/3mhhdbveikc2uTumor-specific cytokine therapy mediated by engineered Salmonella with a synthetic protein delivery system https://www.nature.com/articles/s41598-026-44265-220 Mar 2026 01:07 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mhhdbveikc2uhttps://bsky.app/profile/t3sss.bsky.social/post/3mheizanie22cDksA inhibitors against intracellular and persistent Salmonella are effective in acute models of infection | Science Advances https://www.science.org/doi/10.1126/sciadv.aea683218 Mar 2026 22:12 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mheizanie22chttps://bsky.app/profile/t3sss.bsky.social/post/3mh5fgltkmc2bSerine phosphorylation of CesT by the type III secretion system effectors NleH1 and NleH2 regulates antagonization of CsrA in enteropathogenic Escherichia coli | Infection and Immunity https://journals.asm.org/doi/10.1128/iai.00027-26?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed16 Mar 2026 02:19 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mh5fgltkmc2bhttps://bsky.app/profile/t3sss.bsky.social/post/3mgt2xulb722q Active removal of inhibitory components drives the flagellar Type III Secretion Specificity Switch https://www.biorxiv.org/content/10.64898/2026.03.09.710671v111 Mar 2026 23:45 +0000at://did:plc:n2frewheb6szfvaqnikqlv4f/app.bsky.feed.post/3mgt2xulb722q