We study mechanisms promoting genome stability altered in cancer cellshttps://bsky.app/profile/labvincenzo.bsky.socialhttps://bsky.app/profile/labvincenzo.bsky.social/post/3mopfvqf77s2oNew paper out "Replication stress primes a trophectoderm fate in embryonic stem cells." https://doi.org/10.1038/s41420-026-03169-w20 Jun 2026 08:12 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3mopfvqf77s2ohttps://bsky.app/profile/labvincenzo.bsky.social/post/3mhmsgkk75c23https://www.sciencedirect.com/science/article/pii/S1097276526001322?dgcid=author22 Mar 2026 05:22 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3mhmsgkk75c23https://bsky.app/profile/labvincenzo.bsky.social/post/3mhmmosskm22dExcited to share our new review in Molecular Cell on replicative single-stranded DNA gaps and their role in genome instability and cancer therapy. #DNARepair #ReplicationStress #GenomeStability #CancerResearch #MolecularBiology #PARPinhibitors​​​​​​​​​​​​​​​​ https://www.cell.com/molecular-cell/abstract/S1097-2765(26)00132-222 Mar 2026 03:39 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3mhmmosskm22dhttps://bsky.app/profile/labvincenzo.bsky.social/post/3mgcipeupdk24Pleased to share our paper. We found surprising widespread glycogen accumulation in A-T due to mitochondrial impairment that can be improved by targeting the unexpected FNIP2-SERCA2b-axis. #AtaxiaTelangiectasia #ATM #RareDisease #Metabolism #Mitochondria https://www.nature.com/articles/s41419-026-08507-505 Mar 2026 09:36 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3mgcipeupdk24https://bsky.app/profile/labvincenzo.bsky.social/post/3lo6dn5wj2s2vThree days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together!02 May 2025 07:50 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3lo6dn5wj2s2vhttps://bsky.app/profile/labvincenzo.bsky.social/post/3llhbaoyxo22thttps://www.science.org/doi/10.1126/sciadv.ads322728 Mar 2025 16:45 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3llhbaoyxo22thttps://bsky.app/profile/labvincenzo.bsky.social/post/3lfwpaxkbek2aJoin the first Keystone conference dedicated to DNA replication gaps and cancer! Send an abstract to be selected for a talk. https://www.keystonesymposia.org/conferences/conference-listing/meeting/d5202517 Jan 2025 11:35 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3lfwpaxkbek2ahttps://bsky.app/profile/labvincenzo.bsky.social/post/3lfwpaxkbek2aJoin the first Keystone conference dedicated to DNA replication gaps and cancer! Send an abstract to be selected for a talk. https://www.keystonesymposia.org/conferences/conference-listing/meeting/d5202517 Jan 2025 11:35 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3lfwpaxkbek2ahttps://bsky.app/profile/labvincenzo.bsky.social/post/3lclftwrsks23https://www.science.org/doi/10.1126/science.adr792005 Dec 2024 19:32 +0000at://did:plc:nndjcetup2odyevf2gdal4e7/app.bsky.feed.post/3lclftwrsks23