https://bsky.app/profile/mariahondele.bsky.socialhttps://bsky.app/profile/mariahondele.bsky.social/post/3mzg7y5lyes2hNew preprint alert! 🫧🔬🧬 https://www.biorxiv.org/content/10.64898/2026.09.29.755056v103 Nov 2026 16:09 +0000at://did:plc:ort3ya2tjtc3ebeihlu6dced/app.bsky.feed.post/3mzg7y5lyes2hhttps://bsky.app/profile/mariahondele.bsky.social/post/3mwomb3pv5c2tNuclear speckles are “hot”, but how do they actually sequester mRNPs? We find that stalled mRNPs are retained in nuclear speckles by a combinatorial RNA-binding protein network. https://www.biorxiv.org/content/10.64898/2026.09.28.754972v129 Sep 2026 19:54 +0000at://did:plc:ort3ya2tjtc3ebeihlu6dced/app.bsky.feed.post/3mwomb3pv5c2thttps://bsky.app/profile/mariahondele.bsky.social/post/3mvsmmixu3k2oThe heatwave is finally over - just in time for our “Frosty Foci” to finally come online! ❄️🦠 We found that E. coli builds a transient nucleolus-like ribosome biogenesis compartment during cold adaptation, when RNA (mis)folding makes ribosome biogenesis challenging.18 Sep 2026 16:46 +0000at://did:plc:ort3ya2tjtc3ebeihlu6dced/app.bsky.feed.post/3mvsmmixu3k2ohttps://bsky.app/profile/mariahondele.bsky.social/post/3ms6qft45h22r🚀 New preprint 🥳 Fantastic work by our recent PhD graduate Daan ! How are mRNPs remodeled as they exit the nucleus? We identify PAIP1 as a factor that promotes exchange of the nuclear poly(A)-binding protein PABPN1 for cytoplasmic PABPC1, coupling mRNA export to cytoplasmic mRNP maturation. [contains quote post or other embedded content]03 Aug 2026 14:45 +0000at://did:plc:ort3ya2tjtc3ebeihlu6dced/app.bsky.feed.post/3ms6qft45h22rhttps://bsky.app/profile/mariahondele.bsky.social/post/3mlshtdjyhs25First PhD from the lab - huge congratulations to Dr. Daan on a fantastic defense and really beautiful work!14 May 2026 09:09 +0000at://did:plc:ort3ya2tjtc3ebeihlu6dced/app.bsky.feed.post/3mlshtdjyhs25